RT Journal Article
SR Electronic
T1 Anti-tumor necrosis factor-alpha-induced psoriasis.
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1411
OP 1414
VO 33
IS 7
A1 Ismail Sari
A1 Servet Akar
A1 Merih Birlik
A1 Banu Sis
A1 Fatos Onen
A1 Nurullah Akkoc
YR 2006
UL http://www.jrheum.org/content/33/7/1411.abstract
AB We describe a patient with rheumatoid arthritis who developed psoriasis during treatment with etanercept; psoriatic lesions resolved completely after the drug was discontinued, but returned on rechallenge. No such adverse skin reaction occurred after switching therapy to infliximab. Through a Medline search we identified 11 reports involving 32 patients who developed psoriasis/psoriasiform eruptions during therapy with tumor necrosis factor-alpha (TNF-alpha) inhibitors. All TNF-alpha blocking agents have been reported to lead to or exacerbate psoriasis. In some cases skin changes were severe enough to discontinue the medication.