PT  - JOURNAL ARTICLE
AU  - Ismail Sari
AU  - Servet Akar
AU  - Merih Birlik
AU  - Banu Sis
AU  - Fatos Onen
AU  - Nurullah Akkoc
TI  - Anti-tumor necrosis factor-alpha-induced psoriasis.
DP  - 2006 Jul 01
TA  - The Journal of Rheumatology
PG  - 1411--1414
VI  - 33
IP  - 7
4099  - http://www.jrheum.org/content/33/7/1411.short
4100  - http://www.jrheum.org/content/33/7/1411.full
SO  - J Rheumatol2006 Jul 01; 33
AB  - We describe a patient with rheumatoid arthritis who developed psoriasis during treatment with etanercept; psoriatic lesions resolved completely after the drug was discontinued, but returned on rechallenge. No such adverse skin reaction occurred after switching therapy to infliximab. Through a Medline search we identified 11 reports involving 32 patients who developed psoriasis/psoriasiform eruptions during therapy with tumor necrosis factor-alpha (TNF-alpha) inhibitors. All TNF-alpha blocking agents have been reported to lead to or exacerbate psoriasis. In some cases skin changes were severe enough to discontinue the medication.