PT  - JOURNAL ARTICLE
AU  - Garifallia Linardaki
AU  - Olga Katsarou
AU  - Panagiota Ioannidou
AU  - Anastasia Karafoulidou
AU  - Kyriaki Boki
TI  - Effective etanercept treatment for psoriatic arthritis complicating concomitant human immunodeficiency virus and hepatitis C virus infection.
DP  - 2007 Jun 01
TA  - The Journal of Rheumatology
PG  - 1353--1355
VI  - 34
IP  - 6
4099  - http://www.jrheum.org/content/34/6/1353.short
4100  - http://www.jrheum.org/content/34/6/1353.full
SO  - J Rheumatol2007 Jun 01; 34
AB  - High levels of tumor necrosis factor-alpha (TNF-alpha) are associated with hepatitis C virus (HCV) infection and all stages of human immunodeficiency virus (HIV) infection. TNF-alpha may have a role in both the pathogenesis and the response to treatment of these chronic viral diseases. We describe a 42-year-old HIV/HCV coinfected hemophiliac man who developed psoriasis and severe psoriatic arthritis not responding to combination treatment with methotrexate and cyclosporin A. Treatment with etanercept 25 mg twice weekly was followed by remission of the joint inflammation and improvement of the exanthem. This is the first report of anti-TNF-alpha treatment for rheumatic complications in a patient with both HIV and HCV infection.