TY - JOUR T1 - The role of anti-cyclic citrullinated peptide antibodies in predicting progression of palindromic rheumatism to rheumatoid arthritis. JF - The Journal of Rheumatology JO - J Rheumatol SP - 1240 LP - 1242 VL - 33 IS - 7 AU - Anthony S Russell AU - Al Devani AU - Walter P Maksymowych Y1 - 2006/07/01 UR - http://www.jrheum.org/content/33/7/1240.abstract N2 - OBJECTIVE: To determine whether the presence of anti-cyclic citrullinated peptide (anti-CCP) antibodies at presentation is of prognostic value in patients with palindromic arthritis. METHODS: Stored sera, taken around the time of presentation from patients with palindromic arthritis, where available, were assessed for anti-CCP antibodies, and results were correlated with subsequent clinical outcome. RESULTS:Twenty-nine of 61 patients had progressed to rheumatoid arthritis after a mean followup of 5.4 years; 83% of these had had anti-CCP antibodies in their baseline sera. CONCLUSION: The sensitivity/specificity and likelihood ratios for CCP antibodies were better than rheumatoid factor in predicting outcome. ER -