%PDF-1.4
%
44 0 obj
<>
endobj
41 0 obj
<>
endobj
99 0 obj
<>stream
Acrobat Distiller 4.05 for Macintosh
2005-02-02T15:58:37Z
2024-03-29T05:23:11-07:00
QuarkXPressª 4.11: AdobePS 8.8.0 (301)
2024-03-29T05:23:11-07:00
application/pdf
Heather
2004-67.mar
uuid:0be79c1c-1dd2-11b2-0a00-4e0827bd3700
uuid:0be79c1f-1dd2-11b2-0a00-5b0000000000
endstream
endobj
30 0 obj
<>
endobj
31 0 obj
<>
endobj
45 0 obj
<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/Thumb 16 0 R/Type/Page>>
endobj
1 0 obj
<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/Thumb 18 0 R/Type/Page>>
endobj
4 0 obj
<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/Thumb 20 0 R/Type/Page>>
endobj
7 0 obj
<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/Thumb 22 0 R/Type/Page>>
endobj
10 0 obj
<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/Thumb 24 0 R/Type/Page>>
endobj
117 0 obj
[121 0 R]
endobj
118 0 obj
<>stream
1 g
/GS0 gs
0 792 m
0 792 l
f
q
12 789 587 -785 re
W n
q
0 792.03 612 -792 re
W n
BT
0 0 0 1 k
/GS1 gs
/T1_0 1 Tf
-0.00011 Tc 0.02499 Tw 8 0 0 8 73.4258 737.5319 Tm
[(expression in human glomerulonephritis and renal vasculitis. )54.8 (Am )]TJ
0 Tc 0 -1.25 TD
(J Kidney Dis 2000;36:498-506.)Tj
-0.00011 Tc -2.175 -1.25 Td
[(26.)-875.1 (Patarca R, )17.7 (W)79.9 (ei FY)128.8 (, Singh P)110.7 (, Morasso MI, Cantor H. Dysregulated)]TJ
2.175 -1.25 Td
[(expression of the )17.7 (T)-257.1 (cell cytokine Eta-1 in CD4-8- lymphocytes )]TJ
T*
(during the development of murine autoimmune disease. J Exp Med)Tj
0 Tc 0 Tw T*
[(1990;172:1)36.9 (177-83.)]TJ
-0.00011 Tc 0.02499 Tw -2.175 -1.25 Td
[(27.)-875.1 (Lampe MA, Patarca R, Iregui MV)128.8 (, Cantor H. Polyclonal B cell )]TJ
2.175 -1.25 Td
(activation by the Eta-1 cytokine and the development of systemic)Tj
T*
(autoimmune disease. J Immunol 1991;147:2902-6.)Tj
-2.175 -1.25 Td
[(28.)-875.1 (Forton )54.8 (AC, Petri MA, Goldman D, Sullivan KE. )54.8 (An osteopontin)]TJ
2.175 -1.25 Td
(\(SPP1\) polymorphism is associated with systemic lupus )Tj
T*
(erythematosus. Hum Mutat 2002;19:459.)Tj
-2.175 -1.25 Td
[(29.)-875.1 (Chabas D, Baranzini SE, Mitchell D, et al. )17.7 (The influence of the)]TJ
2.175 -1.25 Td
(proinflammatory cytokine, osteopontin, on autoimmune )Tj
T*
(demyelinating disease. Science 2001;294:1731-5.)Tj
30.8822 17.5 Td
[(30.)-875.1 (Niino M, Kikuchi S, Fukazawa )17.7 (T)74 (,)-0.1 ( )36.8 (Y)99.8 (abe I, )17.7 (T)69.9 (ashiro K. Genetic )]TJ
2.175 -1.25 Td
(polymorphisms of osteopontin in association with multiple sclerosis)Tj
T*
(in Japanese patients. J Neuroimmunol 2003;136:125-9.)Tj
-2.175 -1.25 Td
[(31.)-875.1 (Iwasaki H, Shinohara )36.8 (Y)128.9 (, Ezura )36.8 (Y)128.9 (, et al. )17.7 (Thirteen single-nucleotide)]TJ
2.175 -1.25 Td
(polymorphisms in the human osteopontin gene identified by)Tj
T*
(sequencing of the entire gene in Japanese individuals. J Hum Genet)Tj
0 Tc 0 Tw T*
(2001;46:544-6.)Tj
-0.00011 Tc 0.02499 Tw -2.175 -1.25 Td
[(32.)-875.1 (Masuda H, )17.7 (T)69.9 (akahashi )36.8 (Y)128.9 (,)-0.1 ( )54.8 (Asai S, )17.7 (T)69.9 (akayama )17.7 (T)74 (. Distinct gene )]TJ
2.175 -1.25 Td
[(expression of osteopontin in patients with ulcerative colitis. J Sur)17.7 (g)]TJ
0 Tc T*
[(Res 2003;1)36.9 (1)36.9 (1:85-90.)]TJ
-0.00011 Tc -2.175 -1.25 Td
[(33.)-875.1 (Mochida S, Hashimoto M, Matsui )54.8 (A, et al. Genetic polymorphisms)]TJ
2.175 -1.25 Td
(in promoter region of osteopontin gene may be a marker reflecting)Tj
T*
(hepatitis activity in chronic hepatitis C patients. Biochem Biophys)Tj
0 Tc T*
(Res Commun 2004;313:1079-85.)Tj
ET
0 0 0 1 K
52.97 77 m
557.97 77 l
S
0 0 0 0 k
493.79 69.86 64.18 -15.66 re
f*
BT
0 0 0 1 k
/T1_1 1 Tf
0 Tw 8 0 0 8 544.968 56.9344 Tm
(409)Tj
ET
0 0 0 0 k
53.03 70.9 203 -16.99 re
f*
BT
0 0 0 1 k
/T1_1 1 Tf
-0.00011 Tc 0.02499 Tw 8 0 0 8 54.032 56.641 Tm
[(Ur)36.8 (celay)54.8 (, et al: Osteopontin polymorphisms in RA)]TJ
ET
0 0 0 0 k
/GS0 gs
103.13 82.08 407.5 -10.83 re
f*
0.5 w
103.13 82.08 407.5 -10.83 re
S
Q
Q
q
0 0 612 792 re
W n
BT
0 g
/GS2 gs
/T1_2 8 Tf
108.828 74 Td
(Personal non-commercial use only. The Journal of Rheumatology Copyright\
\251 2005. All rights reserved.)Tj
ET
Q
BT
0 g
/GS2 gs
/T1_3 1 Tf
10 0 0 10 540 17 Tm
( )Tj
0 0.48627 0.77255 rg
/GS2 gs
-7.22298 0 Td
(www.jrheum.org)Tj
0 g
/GS2 gs
-16.72996 0 Td
(Downloaded on March 29, 2024 from )Tj
ET
endstream
endobj
24 0 obj
<>stream
8;Z\tCCYtN%"j!.$g'KK9B)b+!^gH^L;+m2/SuP(MOF6,i")-_^RCkrK4aXR?dh2b
=UY]8EPfBo?117o)H,droG&hPM.tU\'A6Lo_[8/%UL%:!HYt8mU*.g0mVk8>RmipM
*uW)L\X2=.D?Hpj)h4j[OBN7OjY,(=NaGK'k+l0\HUg3:`$1\^0roE3bCMXp]MC#C
"(T?/L2&?-A*D.]m9l
endstream
endobj
28 0 obj
[/Indexed/DeviceRGB 255 27 0 R]
endobj
27 0 obj
<>stream
J,g]g+e/h_!_gCtO=0f)$P%cIi8Zdfc5&3j_8$7g.@L`YKUJNGBP\poR=_;Dl'P(T
(7Boo^^S:71(MN]ZQX/+Cbu.lK"p74pe1T%s.DY%&\1TdJhr54.M9au6>79n6`Q:4
PbLSZTLEE(8E@'*1mg_*eTnN*;*'V3+gm-EEetX%;Bo$ur2ss*N`.-!.kG_q6GDD'
dKoL!8Ka#EV,@V!\j8ZFbp6EE<9cn=N6j0nf;(&;QU6bUD')c@\
9-d\DA=cZ0Q>gIM$$;cd2O@&a;X,Nn_aP(]I1aRc(K1^ue>
gF/(+GaKo$qneLWDrQ#;5\S(\$q'4Q,85`-8;S(=Z"WSBOV*FM)4,?B],R
endstream
endobj
55 0 obj
<>
endobj
50 0 obj
<>
endobj
88 0 obj
<>
endobj
104 0 obj
<>
endobj
56 0 obj
<>
endobj
82 0 obj
<>stream
HtUkPWf6nPƊ݀@"*tay
#BL:^ ,QW@a*٬)_&u5gvVuν}lm0ǧ-]:,tN&Ym]JĿ/mV"ڲbm-EɿEJ_:s]
qYuSs,f4~vhܷw6
qj~m!MlWk:^NAII|>JmPEuJ&+5)ڴ,
U) z^#{JQ5wJŁ'l3@-"챍620,>ð~[&V`ì%l{mll%k%&[[m,IvKJdbB~{j
^;8~;ekr>'[L;ou`AqEMN..Z1Ů=nnWf,g&<3Z3vXd~4ԂeK.ʨy
G"?|bF=GX1a)Flp [X`Z0ر KtlY`DqHnCba x^몎ELR=.\Mn,q4SS^q/8V,D\rz#+#8e]Xk;-]n)!oF
% ! pƳfk [G:W::bWI$Q
nbNܾB45|0 C Fîue2q_VW+ebMJW__l
]K+AO
4YNB ɻhK!#'NgPMRPqt`9u
}7piXb
7R)?Aːć]ݦLߛjG 5̃i '/60(71*N,w(8-z,}Ru^g(Ks>-Sܢ2AKayjEP%}ss:H3ZjC*]x6bLve.>LPÓbq8<=YfLH\=>hPX߱!zĀxoqԫޣ=ea_}weK8k(Bm@3!
8Z>Og53sֱԫ^p;l^F70t(=w4][ÏjiȦR幰!'䌦=p-aww[iv6$w`.L 3'۵kJ^5srX"H);t46$SD5;RƤdaWBKHjjmpPn_?WvwnPV}p!؟M}UUʝzpjOnQ"cNI7`8{VVFR6D^S (_OQ>C孡&