Research ArticleArticle
Does Abatacept Increase Postoperative Adverse Events in Rheumatoid Arthritis Compared with Conventional Synthetic Disease-modifying Drugs?
Hiromu Ito, Shigeyoshi Tsuji, Masanori Nakayama, Yuichi Mochida, Keiichiro Nishida, Hajime Ishikawa, Toshihisa Kojima, Takumi Matsumoto, Ayako Kubota, Takeshi Mochizuki, Koji Sakuraba, Isao Matsushita, Arata Nakajima, Ryota Hara, Akihisa Haraguchi, Tsukasa Matsubara, Katsuaki Kanbe, Natsuko Nakagawa, Masahide Hamaguchi, Shigeki Momohara and the JOSRA Consortium
The Journal of Rheumatology June 2019, jrheum.181100; DOI: https://doi.org/10.3899/jrheum.181100
Hiromu Ito
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Shigeyoshi Tsuji
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Masanori Nakayama
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Yuichi Mochida
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Keiichiro Nishida
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Hajime Ishikawa
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Toshihisa Kojima
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Takumi Matsumoto
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Ayako Kubota
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Takeshi Mochizuki
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Koji Sakuraba
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Isao Matsushita
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Arata Nakajima
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Ryota Hara
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Akihisa Haraguchi
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Tsukasa Matsubara
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Katsuaki Kanbe
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Natsuko Nakagawa
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Masahide Hamaguchi
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
Shigeki Momohara
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
From the Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto; Department of Orthopedic Surgery, Osaka-Minami Medical Center, Kawachi-Nagano; Department of Orthopedic Surgery, Institute of Rheumatology; Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; Department of Orthopedic Surgery, Keio University Graduate School of Medicine, Tokyo; Center for Rheumatic Diseases, Yokohama City Hospital Medical Center, Yokohama; Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama; Department of Rheumatology, Niigata Rheumatic Center, Shibata; Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya; Department of Orthopedic Surgery, Kamagaya General Hospital, Kamagaya; Department of Orthopedic Surgery, Kyushu Medical Center; Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine, Fukuoka; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama; Department of Orthopedic Surgery, Toho University Sakura Medical Center, Sakura; The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University, Nara; Department of Orthopedic Surgery, Matsubara Mayflower Hospital, Kato; Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center, Kakogawa; Department of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan. This work was supported by a research grant from Bristol-Myers Squibb and ONO Pharmaceutical Co. Ltd. (No. IM101-552). H. Ito has received a research grant and/or speaking fee from Bristol-Myers Squibb, Astellas, Asahi-Kasei, and Eli Lilly. S. Tsuji has received speaking fees from Eli Lilly. K. Nishida has received a scholarship donation from Chugai, and speaking fees or other remuneration from Pfizer and from ONO Pharmaceutical Co. T. Kojima has received a research grant from Chugai, Eli Lilly, and Astellas, scholarship donation from Eisai, Daiichi-Sankyo, and Novartis, and speaking fees from Chugai, Diichi-Sankyo, Pfizer, and Astellas. T. Mochizuki has received a speaking fee from Bristol-Myers Squibb, Janssen, and Mochida. I. Matsushita has received speaking fees from Bristol-Myers, Mitsubishi-Tanabe, AbbVie, Eisai, Astellas, and ONO Pharmaceutical Co. T. Matsubara has received speaker honoraria from Pfizer, Nichi-Iko, Astellas, Meiji Seika Ltd., Bristol-Myers Squibb, AbbVie, Janssen, Chugai, Eisai, and Ayumi. K. Kanbe has received speaking fees from Bristol-Myers Squibb and Mitsubishi-Tanabe. H. Ito, MD, PhD, Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine; S. Tsuji, MD, PhD, Department of Orthopedic Surgery, Osaka-Minami Medical Center; M. Nakayama, MD, PhD, Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women’s Medical University; Y. Mochida, MD, PhD, Center for Rheumatic Diseases, Yokohama City Hospital Medical Center; K. Nishida, MD, PhD, Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences; H. Ishikawa, MD, PhD, Department of Rheumatology, Niigata Rheumatic Center; T. Kojima, MD, PhD, Department of Orthopedic Surgery, Nagoya University Hospital; T. Matsumoto, MD, PhD, Department of Orthopedic Surgery, The University of Tokyo Graduate School of Medicine; A. Kubota, MD, PhD, Department of Orthopedic Surgery, Ohmori Medical Center, Toho University School of Medicine; T. Mochizuki, MD, PhD, Department of Orthopedic Surgery, Kamagaya General Hospital; K. Sakuraba, MD, PhD, Department of Orthopedic Surgery, Kyushu Medical Center; I. Matsushita, MD, PhD, Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama; A. Nakajima, MD, PhD, Department of Orthopedic Surgery, Toho University Sakura Medical Center; R. Hara, MD, PhD, The Center for Rheumatic Diseases, Department of Orthopedic Surgery, Nara Medical University; A. Haraguchi, MD, PhD, Department of Orthopedic Surgery, Kyushu University Graduate School of Medicine; T. Matsubara, MD, PhD, Department of Orthopedic Surgery, Matsubara Mayflower Hospital; K. Kanbe, MD, PhD, Department of Orthopedic Surgery, Tokyo Women’s Medical University, Medical Center East; N. Nakagawa, MD, PhD, Department of Orthopedic Surgery, Hyogo Prefectural Kakogawa Medical Center; M. Hamaguchi, MD, PhD, Department of Diabetology, Kameoka Municipal Hospital; S. Momohara, MD, PhD, Department of Orthopedic Surgery, Keio University Graduate School of Medicine. Address correspondence to Dr. H. Ito, the Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto 606-8507, Japan. E-mail: hiromu@kuhp.kyoto-u.ac.jp. Accepted for publication May 23, 2019.
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In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Does Abatacept Increase Postoperative Adverse Events in Rheumatoid Arthritis Compared with Conventional Synthetic Disease-modifying Drugs?
Hiromu Ito, Shigeyoshi Tsuji, Masanori Nakayama, Yuichi Mochida, Keiichiro Nishida, Hajime Ishikawa, Toshihisa Kojima, Takumi Matsumoto, Ayako Kubota, Takeshi Mochizuki, Koji Sakuraba, Isao Matsushita, Arata Nakajima, Ryota Hara, Akihisa Haraguchi, Tsukasa Matsubara, Katsuaki Kanbe, Natsuko Nakagawa, Masahide Hamaguchi, Shigeki Momohara, the JOSRA Consortium
The Journal of Rheumatology Jun 2019, jrheum.181100; DOI: 10.3899/jrheum.181100
Does Abatacept Increase Postoperative Adverse Events in Rheumatoid Arthritis Compared with Conventional Synthetic Disease-modifying Drugs?
Hiromu Ito, Shigeyoshi Tsuji, Masanori Nakayama, Yuichi Mochida, Keiichiro Nishida, Hajime Ishikawa, Toshihisa Kojima, Takumi Matsumoto, Ayako Kubota, Takeshi Mochizuki, Koji Sakuraba, Isao Matsushita, Arata Nakajima, Ryota Hara, Akihisa Haraguchi, Tsukasa Matsubara, Katsuaki Kanbe, Natsuko Nakagawa, Masahide Hamaguchi, Shigeki Momohara, the JOSRA Consortium
The Journal of Rheumatology Jun 2019, jrheum.181100; DOI: 10.3899/jrheum.181100