Research ArticleAccepted Article
Open Access
Long-term, Real-world Safety of Adalimumab in Rheumatoid Arthritis: Analysis of a Prospective US-Based Registry
Leslie R. Harrold, Jenny Griffith, Patrick Zueger, Heather J. Litman, Bernice Gershenson, Syed S. Islam, Christine J. Barr, Dianlin Guo, Jonathan Fay and Jeffrey D. Greenberg
The Journal of Rheumatology August 2019, jrheum.190260; DOI: https://doi.org/10.3899/jrheum.190260
Leslie R. Harrold
From the University of Massachusetts Medical School, Worcester, MA, USA; Corrona, LLC, Waltham, MA, USA; AbbVie, North Chicago, IL, USA; New York University School of Medicine, New York, NY, USA. This study is sponsored by Corrona, LLC. Corrona, LLC has been supported through contracted subscriptions in the last 2 years by AbbVie, Amgen, Boehringer Ingelheim, Bristol-Myers Squibb, Crescendo, Eli Lilly and Company, Genentech, Gilead, GSK, Horizon Pharma USA, Janssen, Momenta Pharmaceuticals, Novartis, Pfizer Inc, Roche, Merck, UCB and Valeant. Financial support for the study was provided by AbbVie. The study design and conduct were a collaboration between Corrona and AbbVie. AbbVie participated in the interpretation of data, review and approval of the manuscript. LR Harrold is an employee and shareholder of Corrona, LLC. She has been a consultant to AbbVie, BMS, and Roche and has a research grant from Pfizer. CJ Barr is an employee and shareholder of Corrona, LLC. HJ Litman is an employee of Corrona, LLC. B Gershenson is an employee of University of Massachusetts Medical School. J Griffith, SS Islam, D Guo, J Fay, and P Zueger are employees of AbbVie Inc. and own AbbVie stock. J Greenberg is an employee and shareholder of Corrona, LLC. He has been a consultant to Genentech, Janssen, Novartis, Pfizer and Eli Lilly.
Jenny Griffith
From the University of Massachusetts Medical School, Worcester, MA, USA; Corrona, LLC, Waltham, MA, USA; AbbVie, North Chicago, IL, USA; New York University School of Medicine, New York, NY, USA. This study is sponsored by Corrona, LLC. Corrona, LLC has been supported through contracted subscriptions in the last 2 years by AbbVie, Amgen, Boehringer Ingelheim, Bristol-Myers Squibb, Crescendo, Eli Lilly and Company, Genentech, Gilead, GSK, Horizon Pharma USA, Janssen, Momenta Pharmaceuticals, Novartis, Pfizer Inc, Roche, Merck, UCB and Valeant. Financial support for the study was provided by AbbVie. The study design and conduct were a collaboration between Corrona and AbbVie. AbbVie participated in the interpretation of data, review and approval of the manuscript. LR Harrold is an employee and shareholder of Corrona, LLC. She has been a consultant to AbbVie, BMS, and Roche and has a research grant from Pfizer. CJ Barr is an employee and shareholder of Corrona, LLC. HJ Litman is an employee of Corrona, LLC. B Gershenson is an employee of University of Massachusetts Medical School. J Griffith, SS Islam, D Guo, J Fay, and P Zueger are employees of AbbVie Inc. and own AbbVie stock. J Greenberg is an employee and shareholder of Corrona, LLC. He has been a consultant to Genentech, Janssen, Novartis, Pfizer and Eli Lilly.
Patrick Zueger
From the University of Massachusetts Medical School, Worcester, MA, USA; Corrona, LLC, Waltham, MA, USA; AbbVie, North Chicago, IL, USA; New York University School of Medicine, New York, NY, USA. This study is sponsored by Corrona, LLC. Corrona, LLC has been supported through contracted subscriptions in the last 2 years by AbbVie, Amgen, Boehringer Ingelheim, Bristol-Myers Squibb, Crescendo, Eli Lilly and Company, Genentech, Gilead, GSK, Horizon Pharma USA, Janssen, Momenta Pharmaceuticals, Novartis, Pfizer Inc, Roche, Merck, UCB and Valeant. Financial support for the study was provided by AbbVie. The study design and conduct were a collaboration between Corrona and AbbVie. AbbVie participated in the interpretation of data, review and approval of the manuscript. LR Harrold is an employee and shareholder of Corrona, LLC. She has been a consultant to AbbVie, BMS, and Roche and has a research grant from Pfizer. CJ Barr is an employee and shareholder of Corrona, LLC. HJ Litman is an employee of Corrona, LLC. B Gershenson is an employee of University of Massachusetts Medical School. J Griffith, SS Islam, D Guo, J Fay, and P Zueger are employees of AbbVie Inc. and own AbbVie stock. J Greenberg is an employee and shareholder of Corrona, LLC. He has been a consultant to Genentech, Janssen, Novartis, Pfizer and Eli Lilly.
Heather J. Litman
From the University of Massachusetts Medical School, Worcester, MA, USA; Corrona, LLC, Waltham, MA, USA; AbbVie, North Chicago, IL, USA; New York University School of Medicine, New York, NY, USA. This study is sponsored by Corrona, LLC. Corrona, LLC has been supported through contracted subscriptions in the last 2 years by AbbVie, Amgen, Boehringer Ingelheim, Bristol-Myers Squibb, Crescendo, Eli Lilly and Company, Genentech, Gilead, GSK, Horizon Pharma USA, Janssen, Momenta Pharmaceuticals, Novartis, Pfizer Inc, Roche, Merck, UCB and Valeant. Financial support for the study was provided by AbbVie. The study design and conduct were a collaboration between Corrona and AbbVie. AbbVie participated in the interpretation of data, review and approval of the manuscript. LR Harrold is an employee and shareholder of Corrona, LLC. She has been a consultant to AbbVie, BMS, and Roche and has a research grant from Pfizer. CJ Barr is an employee and shareholder of Corrona, LLC. HJ Litman is an employee of Corrona, LLC. B Gershenson is an employee of University of Massachusetts Medical School. J Griffith, SS Islam, D Guo, J Fay, and P Zueger are employees of AbbVie Inc. and own AbbVie stock. J Greenberg is an employee and shareholder of Corrona, LLC. He has been a consultant to Genentech, Janssen, Novartis, Pfizer and Eli Lilly.
Bernice Gershenson
From the University of Massachusetts Medical School, Worcester, MA, USA; Corrona, LLC, Waltham, MA, USA; AbbVie, North Chicago, IL, USA; New York University School of Medicine, New York, NY, USA. This study is sponsored by Corrona, LLC. Corrona, LLC has been supported through contracted subscriptions in the last 2 years by AbbVie, Amgen, Boehringer Ingelheim, Bristol-Myers Squibb, Crescendo, Eli Lilly and Company, Genentech, Gilead, GSK, Horizon Pharma USA, Janssen, Momenta Pharmaceuticals, Novartis, Pfizer Inc, Roche, Merck, UCB and Valeant. Financial support for the study was provided by AbbVie. The study design and conduct were a collaboration between Corrona and AbbVie. AbbVie participated in the interpretation of data, review and approval of the manuscript. LR Harrold is an employee and shareholder of Corrona, LLC. She has been a consultant to AbbVie, BMS, and Roche and has a research grant from Pfizer. CJ Barr is an employee and shareholder of Corrona, LLC. HJ Litman is an employee of Corrona, LLC. B Gershenson is an employee of University of Massachusetts Medical School. J Griffith, SS Islam, D Guo, J Fay, and P Zueger are employees of AbbVie Inc. and own AbbVie stock. J Greenberg is an employee and shareholder of Corrona, LLC. He has been a consultant to Genentech, Janssen, Novartis, Pfizer and Eli Lilly.
Syed S. Islam
From the University of Massachusetts Medical School, Worcester, MA, USA; Corrona, LLC, Waltham, MA, USA; AbbVie, North Chicago, IL, USA; New York University School of Medicine, New York, NY, USA. This study is sponsored by Corrona, LLC. Corrona, LLC has been supported through contracted subscriptions in the last 2 years by AbbVie, Amgen, Boehringer Ingelheim, Bristol-Myers Squibb, Crescendo, Eli Lilly and Company, Genentech, Gilead, GSK, Horizon Pharma USA, Janssen, Momenta Pharmaceuticals, Novartis, Pfizer Inc, Roche, Merck, UCB and Valeant. Financial support for the study was provided by AbbVie. The study design and conduct were a collaboration between Corrona and AbbVie. AbbVie participated in the interpretation of data, review and approval of the manuscript. LR Harrold is an employee and shareholder of Corrona, LLC. She has been a consultant to AbbVie, BMS, and Roche and has a research grant from Pfizer. CJ Barr is an employee and shareholder of Corrona, LLC. HJ Litman is an employee of Corrona, LLC. B Gershenson is an employee of University of Massachusetts Medical School. J Griffith, SS Islam, D Guo, J Fay, and P Zueger are employees of AbbVie Inc. and own AbbVie stock. J Greenberg is an employee and shareholder of Corrona, LLC. He has been a consultant to Genentech, Janssen, Novartis, Pfizer and Eli Lilly.
Christine J. Barr
From the University of Massachusetts Medical School, Worcester, MA, USA; Corrona, LLC, Waltham, MA, USA; AbbVie, North Chicago, IL, USA; New York University School of Medicine, New York, NY, USA. This study is sponsored by Corrona, LLC. Corrona, LLC has been supported through contracted subscriptions in the last 2 years by AbbVie, Amgen, Boehringer Ingelheim, Bristol-Myers Squibb, Crescendo, Eli Lilly and Company, Genentech, Gilead, GSK, Horizon Pharma USA, Janssen, Momenta Pharmaceuticals, Novartis, Pfizer Inc, Roche, Merck, UCB and Valeant. Financial support for the study was provided by AbbVie. The study design and conduct were a collaboration between Corrona and AbbVie. AbbVie participated in the interpretation of data, review and approval of the manuscript. LR Harrold is an employee and shareholder of Corrona, LLC. She has been a consultant to AbbVie, BMS, and Roche and has a research grant from Pfizer. CJ Barr is an employee and shareholder of Corrona, LLC. HJ Litman is an employee of Corrona, LLC. B Gershenson is an employee of University of Massachusetts Medical School. J Griffith, SS Islam, D Guo, J Fay, and P Zueger are employees of AbbVie Inc. and own AbbVie stock. J Greenberg is an employee and shareholder of Corrona, LLC. He has been a consultant to Genentech, Janssen, Novartis, Pfizer and Eli Lilly.
Dianlin Guo
From the University of Massachusetts Medical School, Worcester, MA, USA; Corrona, LLC, Waltham, MA, USA; AbbVie, North Chicago, IL, USA; New York University School of Medicine, New York, NY, USA. This study is sponsored by Corrona, LLC. Corrona, LLC has been supported through contracted subscriptions in the last 2 years by AbbVie, Amgen, Boehringer Ingelheim, Bristol-Myers Squibb, Crescendo, Eli Lilly and Company, Genentech, Gilead, GSK, Horizon Pharma USA, Janssen, Momenta Pharmaceuticals, Novartis, Pfizer Inc, Roche, Merck, UCB and Valeant. Financial support for the study was provided by AbbVie. The study design and conduct were a collaboration between Corrona and AbbVie. AbbVie participated in the interpretation of data, review and approval of the manuscript. LR Harrold is an employee and shareholder of Corrona, LLC. She has been a consultant to AbbVie, BMS, and Roche and has a research grant from Pfizer. CJ Barr is an employee and shareholder of Corrona, LLC. HJ Litman is an employee of Corrona, LLC. B Gershenson is an employee of University of Massachusetts Medical School. J Griffith, SS Islam, D Guo, J Fay, and P Zueger are employees of AbbVie Inc. and own AbbVie stock. J Greenberg is an employee and shareholder of Corrona, LLC. He has been a consultant to Genentech, Janssen, Novartis, Pfizer and Eli Lilly.
Jonathan Fay
From the University of Massachusetts Medical School, Worcester, MA, USA; Corrona, LLC, Waltham, MA, USA; AbbVie, North Chicago, IL, USA; New York University School of Medicine, New York, NY, USA. This study is sponsored by Corrona, LLC. Corrona, LLC has been supported through contracted subscriptions in the last 2 years by AbbVie, Amgen, Boehringer Ingelheim, Bristol-Myers Squibb, Crescendo, Eli Lilly and Company, Genentech, Gilead, GSK, Horizon Pharma USA, Janssen, Momenta Pharmaceuticals, Novartis, Pfizer Inc, Roche, Merck, UCB and Valeant. Financial support for the study was provided by AbbVie. The study design and conduct were a collaboration between Corrona and AbbVie. AbbVie participated in the interpretation of data, review and approval of the manuscript. LR Harrold is an employee and shareholder of Corrona, LLC. She has been a consultant to AbbVie, BMS, and Roche and has a research grant from Pfizer. CJ Barr is an employee and shareholder of Corrona, LLC. HJ Litman is an employee of Corrona, LLC. B Gershenson is an employee of University of Massachusetts Medical School. J Griffith, SS Islam, D Guo, J Fay, and P Zueger are employees of AbbVie Inc. and own AbbVie stock. J Greenberg is an employee and shareholder of Corrona, LLC. He has been a consultant to Genentech, Janssen, Novartis, Pfizer and Eli Lilly.
Jeffrey D. Greenberg
From the University of Massachusetts Medical School, Worcester, MA, USA; Corrona, LLC, Waltham, MA, USA; AbbVie, North Chicago, IL, USA; New York University School of Medicine, New York, NY, USA. This study is sponsored by Corrona, LLC. Corrona, LLC has been supported through contracted subscriptions in the last 2 years by AbbVie, Amgen, Boehringer Ingelheim, Bristol-Myers Squibb, Crescendo, Eli Lilly and Company, Genentech, Gilead, GSK, Horizon Pharma USA, Janssen, Momenta Pharmaceuticals, Novartis, Pfizer Inc, Roche, Merck, UCB and Valeant. Financial support for the study was provided by AbbVie. The study design and conduct were a collaboration between Corrona and AbbVie. AbbVie participated in the interpretation of data, review and approval of the manuscript. LR Harrold is an employee and shareholder of Corrona, LLC. She has been a consultant to AbbVie, BMS, and Roche and has a research grant from Pfizer. CJ Barr is an employee and shareholder of Corrona, LLC. HJ Litman is an employee of Corrona, LLC. B Gershenson is an employee of University of Massachusetts Medical School. J Griffith, SS Islam, D Guo, J Fay, and P Zueger are employees of AbbVie Inc. and own AbbVie stock. J Greenberg is an employee and shareholder of Corrona, LLC. He has been a consultant to Genentech, Janssen, Novartis, Pfizer and Eli Lilly.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 3
1 Mar 2024
Accepted manuscript
Long-term, Real-world Safety of Adalimumab in Rheumatoid Arthritis: Analysis of a Prospective US-Based Registry
Leslie R. Harrold, Jenny Griffith, Patrick Zueger, Heather J. Litman, Bernice Gershenson, Syed S. Islam, Christine J. Barr, Dianlin Guo, Jonathan Fay, Jeffrey D. Greenberg
The Journal of Rheumatology Aug 2019, jrheum.190260; DOI: 10.3899/jrheum.190260
Accepted manuscript
Long-term, Real-world Safety of Adalimumab in Rheumatoid Arthritis: Analysis of a Prospective US-Based Registry
Leslie R. Harrold, Jenny Griffith, Patrick Zueger, Heather J. Litman, Bernice Gershenson, Syed S. Islam, Christine J. Barr, Dianlin Guo, Jonathan Fay, Jeffrey D. Greenberg
The Journal of Rheumatology Aug 2019, jrheum.190260; DOI: 10.3899/jrheum.190260