Research ArticleArticle
Biologic and Glucocorticoid Use after Methotrexate Initiation in Patients with Rheumatoid Arthritis
Michael D. George, Brian C. Sauer, Chia-Chen Teng, Grant W. Cannon, Bryant R. England, Gail S. Kerr, Ted R. Mikuls and Joshua F. Baker
The Journal of Rheumatology October 2018, jrheum.180178; DOI: https://doi.org/10.3899/jrheum.180178
Michael D. George
From the Philadelphia Veterans Affairs (VA) Medical Center and University of Pennsylvania, Philadelphia, Pennsylvania; Salt Lake City VA Medical Center and University of Utah, Salt Lake City, Utah; VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center (UNMC), Omaha, Nebraska; DC VA Medical Center, Georgetown and Howard University, Washington, D.C., USA. Dr. George is supported by the Rheumatology Research Foundation Scientist Development Award. Dr. Cannon is supported by Specialty Care Center of Innovation, Veterans Health Administration, Department of Veterans Affairs. Dr. England is supported by the UNMC Physician-Scientist Training Program and UNMC Internal Medicine Scientist Development Award. Dr. Mikuls is supported through funding from a VA Merit Award (CX000896) and from the US National Institutes of Health (National Institute of General Medical Sciences grant U54-GM-115458). Dr. Baker is supported by a VA Clinical Science Research and Development Career Development Award (IK2 CX000955). Drs. Sauer and Cannon receive grant funding from Amgen for unrelated work. The contents of this work do not represent the views of the US Department of Veterans Affairs or the US government. M.D. George, MD, MSCE, University of Pennsylvania, VA Medical Center; B.C. Sauer, PhD, VA Medical Center, University of Utah; C.C. Teng, MS, VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center; G.W. Cannon, MD, VA Medical Center, University of Utah; B.R. England, MD, VA Medical Center, University of Nebraska Medical Center; G.S. Kerr, MD, VA Medical Center, Georgetown and Howard Universities; T.R. Mikuls, MD, MSPH, VA Medical Center, University of Nebraska Medical Center; J.F. Baker, MD, MSCE, VA Medical Center, University of Pennsylvania. Address correspondence to Dr. M.D. George, Division of Rheumatology, 5 White Building, 3400 Spruce St., Philadelphia, Pennsylvania 19104, USA. E-mail: michael.george@uphs.upenn.edu. Accepted for publication July 18, 2018.
Brian C. Sauer
From the Philadelphia Veterans Affairs (VA) Medical Center and University of Pennsylvania, Philadelphia, Pennsylvania; Salt Lake City VA Medical Center and University of Utah, Salt Lake City, Utah; VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center (UNMC), Omaha, Nebraska; DC VA Medical Center, Georgetown and Howard University, Washington, D.C., USA. Dr. George is supported by the Rheumatology Research Foundation Scientist Development Award. Dr. Cannon is supported by Specialty Care Center of Innovation, Veterans Health Administration, Department of Veterans Affairs. Dr. England is supported by the UNMC Physician-Scientist Training Program and UNMC Internal Medicine Scientist Development Award. Dr. Mikuls is supported through funding from a VA Merit Award (CX000896) and from the US National Institutes of Health (National Institute of General Medical Sciences grant U54-GM-115458). Dr. Baker is supported by a VA Clinical Science Research and Development Career Development Award (IK2 CX000955). Drs. Sauer and Cannon receive grant funding from Amgen for unrelated work. The contents of this work do not represent the views of the US Department of Veterans Affairs or the US government. M.D. George, MD, MSCE, University of Pennsylvania, VA Medical Center; B.C. Sauer, PhD, VA Medical Center, University of Utah; C.C. Teng, MS, VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center; G.W. Cannon, MD, VA Medical Center, University of Utah; B.R. England, MD, VA Medical Center, University of Nebraska Medical Center; G.S. Kerr, MD, VA Medical Center, Georgetown and Howard Universities; T.R. Mikuls, MD, MSPH, VA Medical Center, University of Nebraska Medical Center; J.F. Baker, MD, MSCE, VA Medical Center, University of Pennsylvania. Address correspondence to Dr. M.D. George, Division of Rheumatology, 5 White Building, 3400 Spruce St., Philadelphia, Pennsylvania 19104, USA. E-mail: michael.george@uphs.upenn.edu. Accepted for publication July 18, 2018.
Chia-Chen Teng
From the Philadelphia Veterans Affairs (VA) Medical Center and University of Pennsylvania, Philadelphia, Pennsylvania; Salt Lake City VA Medical Center and University of Utah, Salt Lake City, Utah; VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center (UNMC), Omaha, Nebraska; DC VA Medical Center, Georgetown and Howard University, Washington, D.C., USA. Dr. George is supported by the Rheumatology Research Foundation Scientist Development Award. Dr. Cannon is supported by Specialty Care Center of Innovation, Veterans Health Administration, Department of Veterans Affairs. Dr. England is supported by the UNMC Physician-Scientist Training Program and UNMC Internal Medicine Scientist Development Award. Dr. Mikuls is supported through funding from a VA Merit Award (CX000896) and from the US National Institutes of Health (National Institute of General Medical Sciences grant U54-GM-115458). Dr. Baker is supported by a VA Clinical Science Research and Development Career Development Award (IK2 CX000955). Drs. Sauer and Cannon receive grant funding from Amgen for unrelated work. The contents of this work do not represent the views of the US Department of Veterans Affairs or the US government. M.D. George, MD, MSCE, University of Pennsylvania, VA Medical Center; B.C. Sauer, PhD, VA Medical Center, University of Utah; C.C. Teng, MS, VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center; G.W. Cannon, MD, VA Medical Center, University of Utah; B.R. England, MD, VA Medical Center, University of Nebraska Medical Center; G.S. Kerr, MD, VA Medical Center, Georgetown and Howard Universities; T.R. Mikuls, MD, MSPH, VA Medical Center, University of Nebraska Medical Center; J.F. Baker, MD, MSCE, VA Medical Center, University of Pennsylvania. Address correspondence to Dr. M.D. George, Division of Rheumatology, 5 White Building, 3400 Spruce St., Philadelphia, Pennsylvania 19104, USA. E-mail: michael.george@uphs.upenn.edu. Accepted for publication July 18, 2018.
Grant W. Cannon
From the Philadelphia Veterans Affairs (VA) Medical Center and University of Pennsylvania, Philadelphia, Pennsylvania; Salt Lake City VA Medical Center and University of Utah, Salt Lake City, Utah; VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center (UNMC), Omaha, Nebraska; DC VA Medical Center, Georgetown and Howard University, Washington, D.C., USA. Dr. George is supported by the Rheumatology Research Foundation Scientist Development Award. Dr. Cannon is supported by Specialty Care Center of Innovation, Veterans Health Administration, Department of Veterans Affairs. Dr. England is supported by the UNMC Physician-Scientist Training Program and UNMC Internal Medicine Scientist Development Award. Dr. Mikuls is supported through funding from a VA Merit Award (CX000896) and from the US National Institutes of Health (National Institute of General Medical Sciences grant U54-GM-115458). Dr. Baker is supported by a VA Clinical Science Research and Development Career Development Award (IK2 CX000955). Drs. Sauer and Cannon receive grant funding from Amgen for unrelated work. The contents of this work do not represent the views of the US Department of Veterans Affairs or the US government. M.D. George, MD, MSCE, University of Pennsylvania, VA Medical Center; B.C. Sauer, PhD, VA Medical Center, University of Utah; C.C. Teng, MS, VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center; G.W. Cannon, MD, VA Medical Center, University of Utah; B.R. England, MD, VA Medical Center, University of Nebraska Medical Center; G.S. Kerr, MD, VA Medical Center, Georgetown and Howard Universities; T.R. Mikuls, MD, MSPH, VA Medical Center, University of Nebraska Medical Center; J.F. Baker, MD, MSCE, VA Medical Center, University of Pennsylvania. Address correspondence to Dr. M.D. George, Division of Rheumatology, 5 White Building, 3400 Spruce St., Philadelphia, Pennsylvania 19104, USA. E-mail: michael.george@uphs.upenn.edu. Accepted for publication July 18, 2018.
Bryant R. England
From the Philadelphia Veterans Affairs (VA) Medical Center and University of Pennsylvania, Philadelphia, Pennsylvania; Salt Lake City VA Medical Center and University of Utah, Salt Lake City, Utah; VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center (UNMC), Omaha, Nebraska; DC VA Medical Center, Georgetown and Howard University, Washington, D.C., USA. Dr. George is supported by the Rheumatology Research Foundation Scientist Development Award. Dr. Cannon is supported by Specialty Care Center of Innovation, Veterans Health Administration, Department of Veterans Affairs. Dr. England is supported by the UNMC Physician-Scientist Training Program and UNMC Internal Medicine Scientist Development Award. Dr. Mikuls is supported through funding from a VA Merit Award (CX000896) and from the US National Institutes of Health (National Institute of General Medical Sciences grant U54-GM-115458). Dr. Baker is supported by a VA Clinical Science Research and Development Career Development Award (IK2 CX000955). Drs. Sauer and Cannon receive grant funding from Amgen for unrelated work. The contents of this work do not represent the views of the US Department of Veterans Affairs or the US government. M.D. George, MD, MSCE, University of Pennsylvania, VA Medical Center; B.C. Sauer, PhD, VA Medical Center, University of Utah; C.C. Teng, MS, VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center; G.W. Cannon, MD, VA Medical Center, University of Utah; B.R. England, MD, VA Medical Center, University of Nebraska Medical Center; G.S. Kerr, MD, VA Medical Center, Georgetown and Howard Universities; T.R. Mikuls, MD, MSPH, VA Medical Center, University of Nebraska Medical Center; J.F. Baker, MD, MSCE, VA Medical Center, University of Pennsylvania. Address correspondence to Dr. M.D. George, Division of Rheumatology, 5 White Building, 3400 Spruce St., Philadelphia, Pennsylvania 19104, USA. E-mail: michael.george@uphs.upenn.edu. Accepted for publication July 18, 2018.
Gail S. Kerr
From the Philadelphia Veterans Affairs (VA) Medical Center and University of Pennsylvania, Philadelphia, Pennsylvania; Salt Lake City VA Medical Center and University of Utah, Salt Lake City, Utah; VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center (UNMC), Omaha, Nebraska; DC VA Medical Center, Georgetown and Howard University, Washington, D.C., USA. Dr. George is supported by the Rheumatology Research Foundation Scientist Development Award. Dr. Cannon is supported by Specialty Care Center of Innovation, Veterans Health Administration, Department of Veterans Affairs. Dr. England is supported by the UNMC Physician-Scientist Training Program and UNMC Internal Medicine Scientist Development Award. Dr. Mikuls is supported through funding from a VA Merit Award (CX000896) and from the US National Institutes of Health (National Institute of General Medical Sciences grant U54-GM-115458). Dr. Baker is supported by a VA Clinical Science Research and Development Career Development Award (IK2 CX000955). Drs. Sauer and Cannon receive grant funding from Amgen for unrelated work. The contents of this work do not represent the views of the US Department of Veterans Affairs or the US government. M.D. George, MD, MSCE, University of Pennsylvania, VA Medical Center; B.C. Sauer, PhD, VA Medical Center, University of Utah; C.C. Teng, MS, VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center; G.W. Cannon, MD, VA Medical Center, University of Utah; B.R. England, MD, VA Medical Center, University of Nebraska Medical Center; G.S. Kerr, MD, VA Medical Center, Georgetown and Howard Universities; T.R. Mikuls, MD, MSPH, VA Medical Center, University of Nebraska Medical Center; J.F. Baker, MD, MSCE, VA Medical Center, University of Pennsylvania. Address correspondence to Dr. M.D. George, Division of Rheumatology, 5 White Building, 3400 Spruce St., Philadelphia, Pennsylvania 19104, USA. E-mail: michael.george@uphs.upenn.edu. Accepted for publication July 18, 2018.
Ted R. Mikuls
From the Philadelphia Veterans Affairs (VA) Medical Center and University of Pennsylvania, Philadelphia, Pennsylvania; Salt Lake City VA Medical Center and University of Utah, Salt Lake City, Utah; VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center (UNMC), Omaha, Nebraska; DC VA Medical Center, Georgetown and Howard University, Washington, D.C., USA. Dr. George is supported by the Rheumatology Research Foundation Scientist Development Award. Dr. Cannon is supported by Specialty Care Center of Innovation, Veterans Health Administration, Department of Veterans Affairs. Dr. England is supported by the UNMC Physician-Scientist Training Program and UNMC Internal Medicine Scientist Development Award. Dr. Mikuls is supported through funding from a VA Merit Award (CX000896) and from the US National Institutes of Health (National Institute of General Medical Sciences grant U54-GM-115458). Dr. Baker is supported by a VA Clinical Science Research and Development Career Development Award (IK2 CX000955). Drs. Sauer and Cannon receive grant funding from Amgen for unrelated work. The contents of this work do not represent the views of the US Department of Veterans Affairs or the US government. M.D. George, MD, MSCE, University of Pennsylvania, VA Medical Center; B.C. Sauer, PhD, VA Medical Center, University of Utah; C.C. Teng, MS, VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center; G.W. Cannon, MD, VA Medical Center, University of Utah; B.R. England, MD, VA Medical Center, University of Nebraska Medical Center; G.S. Kerr, MD, VA Medical Center, Georgetown and Howard Universities; T.R. Mikuls, MD, MSPH, VA Medical Center, University of Nebraska Medical Center; J.F. Baker, MD, MSCE, VA Medical Center, University of Pennsylvania. Address correspondence to Dr. M.D. George, Division of Rheumatology, 5 White Building, 3400 Spruce St., Philadelphia, Pennsylvania 19104, USA. E-mail: michael.george@uphs.upenn.edu. Accepted for publication July 18, 2018.
Joshua F. Baker
From the Philadelphia Veterans Affairs (VA) Medical Center and University of Pennsylvania, Philadelphia, Pennsylvania; Salt Lake City VA Medical Center and University of Utah, Salt Lake City, Utah; VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center (UNMC), Omaha, Nebraska; DC VA Medical Center, Georgetown and Howard University, Washington, D.C., USA. Dr. George is supported by the Rheumatology Research Foundation Scientist Development Award. Dr. Cannon is supported by Specialty Care Center of Innovation, Veterans Health Administration, Department of Veterans Affairs. Dr. England is supported by the UNMC Physician-Scientist Training Program and UNMC Internal Medicine Scientist Development Award. Dr. Mikuls is supported through funding from a VA Merit Award (CX000896) and from the US National Institutes of Health (National Institute of General Medical Sciences grant U54-GM-115458). Dr. Baker is supported by a VA Clinical Science Research and Development Career Development Award (IK2 CX000955). Drs. Sauer and Cannon receive grant funding from Amgen for unrelated work. The contents of this work do not represent the views of the US Department of Veterans Affairs or the US government. M.D. George, MD, MSCE, University of Pennsylvania, VA Medical Center; B.C. Sauer, PhD, VA Medical Center, University of Utah; C.C. Teng, MS, VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center; G.W. Cannon, MD, VA Medical Center, University of Utah; B.R. England, MD, VA Medical Center, University of Nebraska Medical Center; G.S. Kerr, MD, VA Medical Center, Georgetown and Howard Universities; T.R. Mikuls, MD, MSPH, VA Medical Center, University of Nebraska Medical Center; J.F. Baker, MD, MSCE, VA Medical Center, University of Pennsylvania. Address correspondence to Dr. M.D. George, Division of Rheumatology, 5 White Building, 3400 Spruce St., Philadelphia, Pennsylvania 19104, USA. E-mail: michael.george@uphs.upenn.edu. Accepted for publication July 18, 2018.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 3
1 Mar 2024
Biologic and Glucocorticoid Use after Methotrexate Initiation in Patients with Rheumatoid Arthritis
Michael D. George, Brian C. Sauer, Chia-Chen Teng, Grant W. Cannon, Bryant R. England, Gail S. Kerr, Ted R. Mikuls, Joshua F. Baker
The Journal of Rheumatology Oct 2018, jrheum.180178; DOI: 10.3899/jrheum.180178
Biologic and Glucocorticoid Use after Methotrexate Initiation in Patients with Rheumatoid Arthritis
Michael D. George, Brian C. Sauer, Chia-Chen Teng, Grant W. Cannon, Bryant R. England, Gail S. Kerr, Ted R. Mikuls, Joshua F. Baker
The Journal of Rheumatology Oct 2018, jrheum.180178; DOI: 10.3899/jrheum.180178