Research ArticleArticle
Pulmonary Manifestations and Progression of Lung Disease in Juvenile-onset Mixed Connective Tissue Disease
Siri Opsahl Hetlevik, Berit Flatø, Trond Mogens Aaløkken, May Brit Lund, Silje Reiseter, Georg Karl Mynarek, Ellen Nordal, Marite Rygg and Vibke Lilleby
The Journal of Rheumatology August 2018, jrheum.180019; DOI: https://doi.org/10.3899/jrheum.180019
Siri Opsahl Hetlevik
From the Department of Rheumatology, the Department of Radiology and Nuclear Medicine, and the Department of Respiratory Medicine, Oslo University Hospital, Rikshospitalet; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo; Department of Pediatrics, University Hospital of North Norway; Institute of Clinical Medicine, University of Tromsø, Tromsø; Department of Pediatrics, St. Olavs Hospital; Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. This study was funded by The Norwegian Rheumatism Association and made possible by the Norwegian ExtraFoundation for Health and Rehabilitation. S.O. Hetlevik, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet; B. Flatø, MD, PhD, Professor, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; T.M. Aaløkken, MD, PhD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; M.B. Lund, MD, PhD, Professor, Department of Respiratory Medicine, Oslo University Hospital, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; S. Reiseter, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; G.K. Mynarek, MD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Institute of Clinical Medicine, University of Tromsø; M. Rygg, MD, PhD, Professor, Department of Pediatrics, St. Olavs Hospital, and Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology; V. Lilleby, MD, PhD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet. Address correspondence to Dr. S.O. Hetlevik, Oslo University Hospital – Rikshospitalet, Pb 4950 Nydalen, 0424 Oslo, Norway. E-mail: siri.opsahl@gmail.com. Accepted for publication May 10, 2018.
Berit Flatø
From the Department of Rheumatology, the Department of Radiology and Nuclear Medicine, and the Department of Respiratory Medicine, Oslo University Hospital, Rikshospitalet; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo; Department of Pediatrics, University Hospital of North Norway; Institute of Clinical Medicine, University of Tromsø, Tromsø; Department of Pediatrics, St. Olavs Hospital; Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. This study was funded by The Norwegian Rheumatism Association and made possible by the Norwegian ExtraFoundation for Health and Rehabilitation. S.O. Hetlevik, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet; B. Flatø, MD, PhD, Professor, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; T.M. Aaløkken, MD, PhD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; M.B. Lund, MD, PhD, Professor, Department of Respiratory Medicine, Oslo University Hospital, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; S. Reiseter, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; G.K. Mynarek, MD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Institute of Clinical Medicine, University of Tromsø; M. Rygg, MD, PhD, Professor, Department of Pediatrics, St. Olavs Hospital, and Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology; V. Lilleby, MD, PhD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet. Address correspondence to Dr. S.O. Hetlevik, Oslo University Hospital – Rikshospitalet, Pb 4950 Nydalen, 0424 Oslo, Norway. E-mail: siri.opsahl@gmail.com. Accepted for publication May 10, 2018.
Trond Mogens Aaløkken
From the Department of Rheumatology, the Department of Radiology and Nuclear Medicine, and the Department of Respiratory Medicine, Oslo University Hospital, Rikshospitalet; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo; Department of Pediatrics, University Hospital of North Norway; Institute of Clinical Medicine, University of Tromsø, Tromsø; Department of Pediatrics, St. Olavs Hospital; Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. This study was funded by The Norwegian Rheumatism Association and made possible by the Norwegian ExtraFoundation for Health and Rehabilitation. S.O. Hetlevik, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet; B. Flatø, MD, PhD, Professor, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; T.M. Aaløkken, MD, PhD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; M.B. Lund, MD, PhD, Professor, Department of Respiratory Medicine, Oslo University Hospital, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; S. Reiseter, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; G.K. Mynarek, MD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Institute of Clinical Medicine, University of Tromsø; M. Rygg, MD, PhD, Professor, Department of Pediatrics, St. Olavs Hospital, and Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology; V. Lilleby, MD, PhD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet. Address correspondence to Dr. S.O. Hetlevik, Oslo University Hospital – Rikshospitalet, Pb 4950 Nydalen, 0424 Oslo, Norway. E-mail: siri.opsahl@gmail.com. Accepted for publication May 10, 2018.
May Brit Lund
From the Department of Rheumatology, the Department of Radiology and Nuclear Medicine, and the Department of Respiratory Medicine, Oslo University Hospital, Rikshospitalet; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo; Department of Pediatrics, University Hospital of North Norway; Institute of Clinical Medicine, University of Tromsø, Tromsø; Department of Pediatrics, St. Olavs Hospital; Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. This study was funded by The Norwegian Rheumatism Association and made possible by the Norwegian ExtraFoundation for Health and Rehabilitation. S.O. Hetlevik, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet; B. Flatø, MD, PhD, Professor, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; T.M. Aaløkken, MD, PhD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; M.B. Lund, MD, PhD, Professor, Department of Respiratory Medicine, Oslo University Hospital, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; S. Reiseter, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; G.K. Mynarek, MD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Institute of Clinical Medicine, University of Tromsø; M. Rygg, MD, PhD, Professor, Department of Pediatrics, St. Olavs Hospital, and Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology; V. Lilleby, MD, PhD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet. Address correspondence to Dr. S.O. Hetlevik, Oslo University Hospital – Rikshospitalet, Pb 4950 Nydalen, 0424 Oslo, Norway. E-mail: siri.opsahl@gmail.com. Accepted for publication May 10, 2018.
Silje Reiseter
From the Department of Rheumatology, the Department of Radiology and Nuclear Medicine, and the Department of Respiratory Medicine, Oslo University Hospital, Rikshospitalet; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo; Department of Pediatrics, University Hospital of North Norway; Institute of Clinical Medicine, University of Tromsø, Tromsø; Department of Pediatrics, St. Olavs Hospital; Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. This study was funded by The Norwegian Rheumatism Association and made possible by the Norwegian ExtraFoundation for Health and Rehabilitation. S.O. Hetlevik, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet; B. Flatø, MD, PhD, Professor, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; T.M. Aaløkken, MD, PhD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; M.B. Lund, MD, PhD, Professor, Department of Respiratory Medicine, Oslo University Hospital, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; S. Reiseter, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; G.K. Mynarek, MD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Institute of Clinical Medicine, University of Tromsø; M. Rygg, MD, PhD, Professor, Department of Pediatrics, St. Olavs Hospital, and Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology; V. Lilleby, MD, PhD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet. Address correspondence to Dr. S.O. Hetlevik, Oslo University Hospital – Rikshospitalet, Pb 4950 Nydalen, 0424 Oslo, Norway. E-mail: siri.opsahl@gmail.com. Accepted for publication May 10, 2018.
Georg Karl Mynarek
From the Department of Rheumatology, the Department of Radiology and Nuclear Medicine, and the Department of Respiratory Medicine, Oslo University Hospital, Rikshospitalet; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo; Department of Pediatrics, University Hospital of North Norway; Institute of Clinical Medicine, University of Tromsø, Tromsø; Department of Pediatrics, St. Olavs Hospital; Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. This study was funded by The Norwegian Rheumatism Association and made possible by the Norwegian ExtraFoundation for Health and Rehabilitation. S.O. Hetlevik, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet; B. Flatø, MD, PhD, Professor, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; T.M. Aaløkken, MD, PhD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; M.B. Lund, MD, PhD, Professor, Department of Respiratory Medicine, Oslo University Hospital, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; S. Reiseter, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; G.K. Mynarek, MD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Institute of Clinical Medicine, University of Tromsø; M. Rygg, MD, PhD, Professor, Department of Pediatrics, St. Olavs Hospital, and Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology; V. Lilleby, MD, PhD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet. Address correspondence to Dr. S.O. Hetlevik, Oslo University Hospital – Rikshospitalet, Pb 4950 Nydalen, 0424 Oslo, Norway. E-mail: siri.opsahl@gmail.com. Accepted for publication May 10, 2018.
Ellen Nordal
From the Department of Rheumatology, the Department of Radiology and Nuclear Medicine, and the Department of Respiratory Medicine, Oslo University Hospital, Rikshospitalet; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo; Department of Pediatrics, University Hospital of North Norway; Institute of Clinical Medicine, University of Tromsø, Tromsø; Department of Pediatrics, St. Olavs Hospital; Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. This study was funded by The Norwegian Rheumatism Association and made possible by the Norwegian ExtraFoundation for Health and Rehabilitation. S.O. Hetlevik, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet; B. Flatø, MD, PhD, Professor, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; T.M. Aaløkken, MD, PhD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; M.B. Lund, MD, PhD, Professor, Department of Respiratory Medicine, Oslo University Hospital, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; S. Reiseter, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; G.K. Mynarek, MD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Institute of Clinical Medicine, University of Tromsø; M. Rygg, MD, PhD, Professor, Department of Pediatrics, St. Olavs Hospital, and Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology; V. Lilleby, MD, PhD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet. Address correspondence to Dr. S.O. Hetlevik, Oslo University Hospital – Rikshospitalet, Pb 4950 Nydalen, 0424 Oslo, Norway. E-mail: siri.opsahl@gmail.com. Accepted for publication May 10, 2018.
Marite Rygg
From the Department of Rheumatology, the Department of Radiology and Nuclear Medicine, and the Department of Respiratory Medicine, Oslo University Hospital, Rikshospitalet; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo; Department of Pediatrics, University Hospital of North Norway; Institute of Clinical Medicine, University of Tromsø, Tromsø; Department of Pediatrics, St. Olavs Hospital; Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. This study was funded by The Norwegian Rheumatism Association and made possible by the Norwegian ExtraFoundation for Health and Rehabilitation. S.O. Hetlevik, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet; B. Flatø, MD, PhD, Professor, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; T.M. Aaløkken, MD, PhD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; M.B. Lund, MD, PhD, Professor, Department of Respiratory Medicine, Oslo University Hospital, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; S. Reiseter, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; G.K. Mynarek, MD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Institute of Clinical Medicine, University of Tromsø; M. Rygg, MD, PhD, Professor, Department of Pediatrics, St. Olavs Hospital, and Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology; V. Lilleby, MD, PhD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet. Address correspondence to Dr. S.O. Hetlevik, Oslo University Hospital – Rikshospitalet, Pb 4950 Nydalen, 0424 Oslo, Norway. E-mail: siri.opsahl@gmail.com. Accepted for publication May 10, 2018.
Vibke Lilleby
From the Department of Rheumatology, the Department of Radiology and Nuclear Medicine, and the Department of Respiratory Medicine, Oslo University Hospital, Rikshospitalet; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo; Department of Pediatrics, University Hospital of North Norway; Institute of Clinical Medicine, University of Tromsø, Tromsø; Department of Pediatrics, St. Olavs Hospital; Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. This study was funded by The Norwegian Rheumatism Association and made possible by the Norwegian ExtraFoundation for Health and Rehabilitation. S.O. Hetlevik, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet; B. Flatø, MD, PhD, Professor, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; T.M. Aaløkken, MD, PhD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; M.B. Lund, MD, PhD, Professor, Department of Respiratory Medicine, Oslo University Hospital, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; S. Reiseter, MD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo; G.K. Mynarek, MD, Department of Radiology and Nuclear Medicine, Oslo University Hospital; E. Nordal, MD, PhD, Department of Pediatrics, University Hospital of North Norway, and Institute of Clinical Medicine, University of Tromsø; M. Rygg, MD, PhD, Professor, Department of Pediatrics, St. Olavs Hospital, and Institute of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology; V. Lilleby, MD, PhD, Department of Rheumatology, Oslo University Hospital, Rikshospitalet. Address correspondence to Dr. S.O. Hetlevik, Oslo University Hospital – Rikshospitalet, Pb 4950 Nydalen, 0424 Oslo, Norway. E-mail: siri.opsahl@gmail.com. Accepted for publication May 10, 2018.
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In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Pulmonary Manifestations and Progression of Lung Disease in Juvenile-onset Mixed Connective Tissue Disease
Siri Opsahl Hetlevik, Berit Flatø, Trond Mogens Aaløkken, May Brit Lund, Silje Reiseter, Georg Karl Mynarek, Ellen Nordal, Marite Rygg, Vibke Lilleby
The Journal of Rheumatology Aug 2018, jrheum.180019; DOI: 10.3899/jrheum.180019
Pulmonary Manifestations and Progression of Lung Disease in Juvenile-onset Mixed Connective Tissue Disease
Siri Opsahl Hetlevik, Berit Flatø, Trond Mogens Aaløkken, May Brit Lund, Silje Reiseter, Georg Karl Mynarek, Ellen Nordal, Marite Rygg, Vibke Lilleby
The Journal of Rheumatology Aug 2018, jrheum.180019; DOI: 10.3899/jrheum.180019