Research ArticleArticle
Lack of Association among Peptidyl Arginine Deiminase Type 4 Autoantibodies, PADI4 Polymorphisms, and Clinical Characteristics in Rheumatoid Arthritis
Kari Guderud, Marthe Thoresen Mæhlen, Gry Beate Namløs Nordang, Marte Kathrine Viken, Bettina Kulle Andreassen, Øyvind Molberg, Siri Tennebø Flåm and Benedicte Alexandra Lie
The Journal of Rheumatology June 2018, jrheum.170769; DOI: https://doi.org/10.3899/jrheum.170769
Kari Guderud
From the Department of Medical Genetics, and the Department of Immunology, University of Oslo and Oslo University Hospital; K.G. Jebsen Inflammation Research Centre, University of Oslo; Department of Rheumatology, Oslo University Hospital; Department of Rheumatology, Diakonhjemmet Hospital; Department of Research, Cancer Registry of Norway, Institute for Population-based Research, Oslo, Norway. This project is financed by the Southern and Eastern Heath Region of Norway (Helse Sør-Øst). K. Guderud, M Pharm, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; M.T. Mæhlen, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; G.B. Nordang, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital; M.K. Viken, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre; B.K. Andreassen, PhD, Department of Research, Cancer Registry of Norway, Institute for Population-Based Research; Ø. Molberg, PhD, Department of Rheumatology, Oslo University Hospital; S.T. Flåm, BS, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; B.A. Lie, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre. Address correspondence to B.A. Lie, Department of Medical Genetics, Oslo University Hospital, Postboks 4956 Nydalen, 0424 Oslo, Norway. E-mail: b.a.lie@medisin.uio.no. Accepted for publication February 6, 2018.
Marthe Thoresen Mæhlen
From the Department of Medical Genetics, and the Department of Immunology, University of Oslo and Oslo University Hospital; K.G. Jebsen Inflammation Research Centre, University of Oslo; Department of Rheumatology, Oslo University Hospital; Department of Rheumatology, Diakonhjemmet Hospital; Department of Research, Cancer Registry of Norway, Institute for Population-based Research, Oslo, Norway. This project is financed by the Southern and Eastern Heath Region of Norway (Helse Sør-Øst). K. Guderud, M Pharm, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; M.T. Mæhlen, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; G.B. Nordang, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital; M.K. Viken, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre; B.K. Andreassen, PhD, Department of Research, Cancer Registry of Norway, Institute for Population-Based Research; Ø. Molberg, PhD, Department of Rheumatology, Oslo University Hospital; S.T. Flåm, BS, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; B.A. Lie, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre. Address correspondence to B.A. Lie, Department of Medical Genetics, Oslo University Hospital, Postboks 4956 Nydalen, 0424 Oslo, Norway. E-mail: b.a.lie@medisin.uio.no. Accepted for publication February 6, 2018.
Gry Beate Namløs Nordang
From the Department of Medical Genetics, and the Department of Immunology, University of Oslo and Oslo University Hospital; K.G. Jebsen Inflammation Research Centre, University of Oslo; Department of Rheumatology, Oslo University Hospital; Department of Rheumatology, Diakonhjemmet Hospital; Department of Research, Cancer Registry of Norway, Institute for Population-based Research, Oslo, Norway. This project is financed by the Southern and Eastern Heath Region of Norway (Helse Sør-Øst). K. Guderud, M Pharm, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; M.T. Mæhlen, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; G.B. Nordang, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital; M.K. Viken, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre; B.K. Andreassen, PhD, Department of Research, Cancer Registry of Norway, Institute for Population-Based Research; Ø. Molberg, PhD, Department of Rheumatology, Oslo University Hospital; S.T. Flåm, BS, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; B.A. Lie, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre. Address correspondence to B.A. Lie, Department of Medical Genetics, Oslo University Hospital, Postboks 4956 Nydalen, 0424 Oslo, Norway. E-mail: b.a.lie@medisin.uio.no. Accepted for publication February 6, 2018.
Marte Kathrine Viken
From the Department of Medical Genetics, and the Department of Immunology, University of Oslo and Oslo University Hospital; K.G. Jebsen Inflammation Research Centre, University of Oslo; Department of Rheumatology, Oslo University Hospital; Department of Rheumatology, Diakonhjemmet Hospital; Department of Research, Cancer Registry of Norway, Institute for Population-based Research, Oslo, Norway. This project is financed by the Southern and Eastern Heath Region of Norway (Helse Sør-Øst). K. Guderud, M Pharm, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; M.T. Mæhlen, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; G.B. Nordang, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital; M.K. Viken, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre; B.K. Andreassen, PhD, Department of Research, Cancer Registry of Norway, Institute for Population-Based Research; Ø. Molberg, PhD, Department of Rheumatology, Oslo University Hospital; S.T. Flåm, BS, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; B.A. Lie, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre. Address correspondence to B.A. Lie, Department of Medical Genetics, Oslo University Hospital, Postboks 4956 Nydalen, 0424 Oslo, Norway. E-mail: b.a.lie@medisin.uio.no. Accepted for publication February 6, 2018.
Bettina Kulle Andreassen
From the Department of Medical Genetics, and the Department of Immunology, University of Oslo and Oslo University Hospital; K.G. Jebsen Inflammation Research Centre, University of Oslo; Department of Rheumatology, Oslo University Hospital; Department of Rheumatology, Diakonhjemmet Hospital; Department of Research, Cancer Registry of Norway, Institute for Population-based Research, Oslo, Norway. This project is financed by the Southern and Eastern Heath Region of Norway (Helse Sør-Øst). K. Guderud, M Pharm, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; M.T. Mæhlen, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; G.B. Nordang, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital; M.K. Viken, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre; B.K. Andreassen, PhD, Department of Research, Cancer Registry of Norway, Institute for Population-Based Research; Ø. Molberg, PhD, Department of Rheumatology, Oslo University Hospital; S.T. Flåm, BS, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; B.A. Lie, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre. Address correspondence to B.A. Lie, Department of Medical Genetics, Oslo University Hospital, Postboks 4956 Nydalen, 0424 Oslo, Norway. E-mail: b.a.lie@medisin.uio.no. Accepted for publication February 6, 2018.
Øyvind Molberg
From the Department of Medical Genetics, and the Department of Immunology, University of Oslo and Oslo University Hospital; K.G. Jebsen Inflammation Research Centre, University of Oslo; Department of Rheumatology, Oslo University Hospital; Department of Rheumatology, Diakonhjemmet Hospital; Department of Research, Cancer Registry of Norway, Institute for Population-based Research, Oslo, Norway. This project is financed by the Southern and Eastern Heath Region of Norway (Helse Sør-Øst). K. Guderud, M Pharm, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; M.T. Mæhlen, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; G.B. Nordang, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital; M.K. Viken, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre; B.K. Andreassen, PhD, Department of Research, Cancer Registry of Norway, Institute for Population-Based Research; Ø. Molberg, PhD, Department of Rheumatology, Oslo University Hospital; S.T. Flåm, BS, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; B.A. Lie, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre. Address correspondence to B.A. Lie, Department of Medical Genetics, Oslo University Hospital, Postboks 4956 Nydalen, 0424 Oslo, Norway. E-mail: b.a.lie@medisin.uio.no. Accepted for publication February 6, 2018.
Siri Tennebø Flåm
From the Department of Medical Genetics, and the Department of Immunology, University of Oslo and Oslo University Hospital; K.G. Jebsen Inflammation Research Centre, University of Oslo; Department of Rheumatology, Oslo University Hospital; Department of Rheumatology, Diakonhjemmet Hospital; Department of Research, Cancer Registry of Norway, Institute for Population-based Research, Oslo, Norway. This project is financed by the Southern and Eastern Heath Region of Norway (Helse Sør-Øst). K. Guderud, M Pharm, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; M.T. Mæhlen, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; G.B. Nordang, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital; M.K. Viken, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre; B.K. Andreassen, PhD, Department of Research, Cancer Registry of Norway, Institute for Population-Based Research; Ø. Molberg, PhD, Department of Rheumatology, Oslo University Hospital; S.T. Flåm, BS, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; B.A. Lie, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre. Address correspondence to B.A. Lie, Department of Medical Genetics, Oslo University Hospital, Postboks 4956 Nydalen, 0424 Oslo, Norway. E-mail: b.a.lie@medisin.uio.no. Accepted for publication February 6, 2018.
Benedicte Alexandra Lie
From the Department of Medical Genetics, and the Department of Immunology, University of Oslo and Oslo University Hospital; K.G. Jebsen Inflammation Research Centre, University of Oslo; Department of Rheumatology, Oslo University Hospital; Department of Rheumatology, Diakonhjemmet Hospital; Department of Research, Cancer Registry of Norway, Institute for Population-based Research, Oslo, Norway. This project is financed by the Southern and Eastern Heath Region of Norway (Helse Sør-Øst). K. Guderud, M Pharm, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; M.T. Mæhlen, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; G.B. Nordang, PhD, Department of Medical Genetics, University of Oslo and Oslo University Hospital; M.K. Viken, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre; B.K. Andreassen, PhD, Department of Research, Cancer Registry of Norway, Institute for Population-Based Research; Ø. Molberg, PhD, Department of Rheumatology, Oslo University Hospital; S.T. Flåm, BS, Department of Medical Genetics, and the K.G. Jebsen Inflammation Research Centre, University of Oslo and Oslo University Hospital; B.A. Lie, PhD, Department of Medical Genetics, and Department of Immunology, University of Oslo and Oslo University Hospital, and K.G. Jebsen Inflammation Research Centre. Address correspondence to B.A. Lie, Department of Medical Genetics, Oslo University Hospital, Postboks 4956 Nydalen, 0424 Oslo, Norway. E-mail: b.a.lie@medisin.uio.no. Accepted for publication February 6, 2018.
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The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Lack of Association among Peptidyl Arginine Deiminase Type 4 Autoantibodies, PADI4 Polymorphisms, and Clinical Characteristics in Rheumatoid Arthritis
Kari Guderud, Marthe Thoresen Mæhlen, Gry Beate Namløs Nordang, Marte Kathrine Viken, Bettina Kulle Andreassen, Øyvind Molberg, Siri Tennebø Flåm, Benedicte Alexandra Lie
The Journal of Rheumatology Jun 2018, jrheum.170769; DOI: 10.3899/jrheum.170769
Lack of Association among Peptidyl Arginine Deiminase Type 4 Autoantibodies, PADI4 Polymorphisms, and Clinical Characteristics in Rheumatoid Arthritis
Kari Guderud, Marthe Thoresen Mæhlen, Gry Beate Namløs Nordang, Marte Kathrine Viken, Bettina Kulle Andreassen, Øyvind Molberg, Siri Tennebø Flåm, Benedicte Alexandra Lie
The Journal of Rheumatology Jun 2018, jrheum.170769; DOI: 10.3899/jrheum.170769