Research ArticleArticle
Antifibrillarin Antibodies Are Associated with Native North American Ethnicity and Poorer Survival in Systemic Sclerosis
Carolina Mejia Otero, Shervin Assassi, Marie Hudson, Maureen D. Mayes, Rosa Estrada-Y-Martin, Claudia Pedroza, Tingting W. Mills, Jennifer Walker, Murray Baron, Wendy Stevens, Susanna M. Proudman, Mandana Nikpour, Sonal Mehra, Mianbo Wang, Marvin J. Fritzler, the Canadian Scleroderma Research Group, Australian Scleroderma Cohort Study and Genetics versus Environment in Scleroderma Outcome Study
The Journal of Rheumatology April 2017, jrheum.160574; DOI: https://doi.org/10.3899/jrheum.160574
Carolina Mejia Otero
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Shervin Assassi
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Marie Hudson
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Maureen D. Mayes
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Rosa Estrada-Y-Martin
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Claudia Pedroza
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Tingting W. Mills
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Jennifer Walker
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Murray Baron
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Wendy Stevens
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Susanna M. Proudman
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Mandana Nikpour
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Sonal Mehra
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Mianbo Wang
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
Marvin J. Fritzler
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
From the Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA; Department of Medicine, McGill University; Rheumatology Unit, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec; Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide; Department of Allergy and Immunology, Flinders Medical Centre, Bedford Park; Department of Rheumatology, St. Vincent’s Hospital Melbourne, Fitzroy; Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Victoria, Australia. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. Dr. Nikpour holds a University of Melbourne Faculty of Medicine Dentistry and Health Science David Bickart Clinician Researcher Fellowship, and is a recipient of a National Health and Medical Research Council research fellowship (APP1071735). Dr. Assassi is funded by the US National Institutes of Health (NIH)/US National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) K23AR061436. Dr. Mayes is funded by NIH/NIAMS AR055258. C. Mejia Otero, MD, Clinical Fellow, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; S. Assassi, MD, Faculty, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; M. Hudson, MD, Faculty, Department of Medicine, McGill University; M.D. Mayes, MD, Division of Rheumatology and Immunogenetics, University of Texas McGovern Medical School; R. Estrada-Y-Martin, MD, Faculty, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas McGovern Medical School; C. Pedroza, PhD, Faculty, Center for Evidence Based Medicine and Clinical Research, University of Texas McGovern Medical School; T.W. Mills, PhD, Biochemistry and Molecular Biology, University of Texas McGovern Medical School; J. Walker, MD, Faculty, Department of Allergy and Immunology, Flinders Medical Centre; M. Baron, MD, Faculty, Department of Medicine, McGill University; W. Stevens, MD, Faculty, Department of Rheumatology, St. Vincent’s Hospital Melbourne; S.M. Proudman, MD, Faculty, Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide; M. Nikpour, MD, PhD, St. Vincent’s Hospital Melbourne, and Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; S. Mehra, MD, Cumming School of Medicine, University of Calgary; M. Wang, MS, staff, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, Professor, Cumming School of Medicine, University of Calgary. Address correspondence to Dr. S. Assassi, Department of Medicine, Division of Rheumatology, University of Texas-Houston, 6431 Fannin, MSB 5.270, Houston, Texas 77030, USA. E-mail: shervin.assassi@uth.tmc.edu. Accepted for publication February 21, 2017.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Antifibrillarin Antibodies Are Associated with Native North American Ethnicity and Poorer Survival in Systemic Sclerosis
Carolina Mejia Otero, Shervin Assassi, Marie Hudson, Maureen D. Mayes, Rosa Estrada-Y-Martin, Claudia Pedroza, Tingting W. Mills, Jennifer Walker, Murray Baron, Wendy Stevens, Susanna M. Proudman, Mandana Nikpour, Sonal Mehra, Mianbo Wang, Marvin J. Fritzler, the Canadian Scleroderma Research Group, Australian Scleroderma Cohort Study, Genetics versus Environment in Scleroderma Outcome Study
The Journal of Rheumatology Apr 2017, jrheum.160574; DOI: 10.3899/jrheum.160574
Antifibrillarin Antibodies Are Associated with Native North American Ethnicity and Poorer Survival in Systemic Sclerosis
Carolina Mejia Otero, Shervin Assassi, Marie Hudson, Maureen D. Mayes, Rosa Estrada-Y-Martin, Claudia Pedroza, Tingting W. Mills, Jennifer Walker, Murray Baron, Wendy Stevens, Susanna M. Proudman, Mandana Nikpour, Sonal Mehra, Mianbo Wang, Marvin J. Fritzler, the Canadian Scleroderma Research Group, Australian Scleroderma Cohort Study, Genetics versus Environment in Scleroderma Outcome Study
The Journal of Rheumatology Apr 2017, jrheum.160574; DOI: 10.3899/jrheum.160574