Research ArticleArticle
Predicting Which Children with Juvenile Idiopathic Arthritis Will Have a Severe Disease Course: Results from the ReACCh-Out Cohort
Jaime Guzman, Andrew Henrey, Thomas Loughin, Roberta A. Berard, Natalie J. Shiff, Roman Jurencak, Susanne M. Benseler and Lori B. Tucker on behalf of the ReACCh-Out Investigators
The Journal of Rheumatology December 2016, jrheum.160197; DOI: https://doi.org/10.3899/jrheum.160197
Jaime Guzman
From the British Columbia Children’s Hospital and the University of British Columbia, Vancouver; Simon Fraser University, Burnaby, British Columbia; the Alberta Children’s Hospital and University of Calgary, Calgary, Alberta; London Health Sciences Centre and Western University, London; the Children’s Hospital of Eastern Ontario and University of Ottawa, Ottawa, Ontario, Canada; the Shands Children’s Hospital and University of Florida, Gainesville, Florida, USA. Funded by a grant from the Canadian Initiative for Outcomes in Rheumatology Care, Canadian Rheumatology Association. The Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh-Out) cohort was funded by a New Emerging Team research grant from the Canadian Institutes of Health Research. Dr. Guzman was funded by a Clinical Investigator Award from the Child and Family Research Institute, Vancouver, British Columbia, Canada. J. Guzman, MD, MSc, British Columbia Children’s Hospital and the University of British Columbia; A. Henrey, PhD, Simon Fraser University; T. Loughin, PhD, Professor, Simon Fraser University; R.A. Berard, MD, MSc, London Health Sciences Centre and Western University; N.J. Shiff, MD, MSc, Shands Children’s Hospital and University of Florida; R. Jurencak, MD, Children’s Hospital of Eastern Ontario and University of Ottawa; S.M. Benseler, MD, PhD, Alberta Children’s Hospital and University of Calgary; L.B. Tucker, MD, British Columbia Children’s Hospital and the University of British Columbia. Address reprint requests to Dr. J. Guzman, Division of Pediatric Rheumatology, BC Children’s Hospital, 4500 Oak St., Suite K4-122, Vancouver, British Columbia V6H 3N1, Canada. E-mail: jguzman@cw.bc.ca. Accepted for publication October 25, 2016.
Andrew Henrey
From the British Columbia Children’s Hospital and the University of British Columbia, Vancouver; Simon Fraser University, Burnaby, British Columbia; the Alberta Children’s Hospital and University of Calgary, Calgary, Alberta; London Health Sciences Centre and Western University, London; the Children’s Hospital of Eastern Ontario and University of Ottawa, Ottawa, Ontario, Canada; the Shands Children’s Hospital and University of Florida, Gainesville, Florida, USA. Funded by a grant from the Canadian Initiative for Outcomes in Rheumatology Care, Canadian Rheumatology Association. The Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh-Out) cohort was funded by a New Emerging Team research grant from the Canadian Institutes of Health Research. Dr. Guzman was funded by a Clinical Investigator Award from the Child and Family Research Institute, Vancouver, British Columbia, Canada. J. Guzman, MD, MSc, British Columbia Children’s Hospital and the University of British Columbia; A. Henrey, PhD, Simon Fraser University; T. Loughin, PhD, Professor, Simon Fraser University; R.A. Berard, MD, MSc, London Health Sciences Centre and Western University; N.J. Shiff, MD, MSc, Shands Children’s Hospital and University of Florida; R. Jurencak, MD, Children’s Hospital of Eastern Ontario and University of Ottawa; S.M. Benseler, MD, PhD, Alberta Children’s Hospital and University of Calgary; L.B. Tucker, MD, British Columbia Children’s Hospital and the University of British Columbia. Address reprint requests to Dr. J. Guzman, Division of Pediatric Rheumatology, BC Children’s Hospital, 4500 Oak St., Suite K4-122, Vancouver, British Columbia V6H 3N1, Canada. E-mail: jguzman@cw.bc.ca. Accepted for publication October 25, 2016.
Thomas Loughin
From the British Columbia Children’s Hospital and the University of British Columbia, Vancouver; Simon Fraser University, Burnaby, British Columbia; the Alberta Children’s Hospital and University of Calgary, Calgary, Alberta; London Health Sciences Centre and Western University, London; the Children’s Hospital of Eastern Ontario and University of Ottawa, Ottawa, Ontario, Canada; the Shands Children’s Hospital and University of Florida, Gainesville, Florida, USA. Funded by a grant from the Canadian Initiative for Outcomes in Rheumatology Care, Canadian Rheumatology Association. The Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh-Out) cohort was funded by a New Emerging Team research grant from the Canadian Institutes of Health Research. Dr. Guzman was funded by a Clinical Investigator Award from the Child and Family Research Institute, Vancouver, British Columbia, Canada. J. Guzman, MD, MSc, British Columbia Children’s Hospital and the University of British Columbia; A. Henrey, PhD, Simon Fraser University; T. Loughin, PhD, Professor, Simon Fraser University; R.A. Berard, MD, MSc, London Health Sciences Centre and Western University; N.J. Shiff, MD, MSc, Shands Children’s Hospital and University of Florida; R. Jurencak, MD, Children’s Hospital of Eastern Ontario and University of Ottawa; S.M. Benseler, MD, PhD, Alberta Children’s Hospital and University of Calgary; L.B. Tucker, MD, British Columbia Children’s Hospital and the University of British Columbia. Address reprint requests to Dr. J. Guzman, Division of Pediatric Rheumatology, BC Children’s Hospital, 4500 Oak St., Suite K4-122, Vancouver, British Columbia V6H 3N1, Canada. E-mail: jguzman@cw.bc.ca. Accepted for publication October 25, 2016.
Roberta A. Berard
From the British Columbia Children’s Hospital and the University of British Columbia, Vancouver; Simon Fraser University, Burnaby, British Columbia; the Alberta Children’s Hospital and University of Calgary, Calgary, Alberta; London Health Sciences Centre and Western University, London; the Children’s Hospital of Eastern Ontario and University of Ottawa, Ottawa, Ontario, Canada; the Shands Children’s Hospital and University of Florida, Gainesville, Florida, USA. Funded by a grant from the Canadian Initiative for Outcomes in Rheumatology Care, Canadian Rheumatology Association. The Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh-Out) cohort was funded by a New Emerging Team research grant from the Canadian Institutes of Health Research. Dr. Guzman was funded by a Clinical Investigator Award from the Child and Family Research Institute, Vancouver, British Columbia, Canada. J. Guzman, MD, MSc, British Columbia Children’s Hospital and the University of British Columbia; A. Henrey, PhD, Simon Fraser University; T. Loughin, PhD, Professor, Simon Fraser University; R.A. Berard, MD, MSc, London Health Sciences Centre and Western University; N.J. Shiff, MD, MSc, Shands Children’s Hospital and University of Florida; R. Jurencak, MD, Children’s Hospital of Eastern Ontario and University of Ottawa; S.M. Benseler, MD, PhD, Alberta Children’s Hospital and University of Calgary; L.B. Tucker, MD, British Columbia Children’s Hospital and the University of British Columbia. Address reprint requests to Dr. J. Guzman, Division of Pediatric Rheumatology, BC Children’s Hospital, 4500 Oak St., Suite K4-122, Vancouver, British Columbia V6H 3N1, Canada. E-mail: jguzman@cw.bc.ca. Accepted for publication October 25, 2016.
Natalie J. Shiff
From the British Columbia Children’s Hospital and the University of British Columbia, Vancouver; Simon Fraser University, Burnaby, British Columbia; the Alberta Children’s Hospital and University of Calgary, Calgary, Alberta; London Health Sciences Centre and Western University, London; the Children’s Hospital of Eastern Ontario and University of Ottawa, Ottawa, Ontario, Canada; the Shands Children’s Hospital and University of Florida, Gainesville, Florida, USA. Funded by a grant from the Canadian Initiative for Outcomes in Rheumatology Care, Canadian Rheumatology Association. The Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh-Out) cohort was funded by a New Emerging Team research grant from the Canadian Institutes of Health Research. Dr. Guzman was funded by a Clinical Investigator Award from the Child and Family Research Institute, Vancouver, British Columbia, Canada. J. Guzman, MD, MSc, British Columbia Children’s Hospital and the University of British Columbia; A. Henrey, PhD, Simon Fraser University; T. Loughin, PhD, Professor, Simon Fraser University; R.A. Berard, MD, MSc, London Health Sciences Centre and Western University; N.J. Shiff, MD, MSc, Shands Children’s Hospital and University of Florida; R. Jurencak, MD, Children’s Hospital of Eastern Ontario and University of Ottawa; S.M. Benseler, MD, PhD, Alberta Children’s Hospital and University of Calgary; L.B. Tucker, MD, British Columbia Children’s Hospital and the University of British Columbia. Address reprint requests to Dr. J. Guzman, Division of Pediatric Rheumatology, BC Children’s Hospital, 4500 Oak St., Suite K4-122, Vancouver, British Columbia V6H 3N1, Canada. E-mail: jguzman@cw.bc.ca. Accepted for publication October 25, 2016.
Roman Jurencak
From the British Columbia Children’s Hospital and the University of British Columbia, Vancouver; Simon Fraser University, Burnaby, British Columbia; the Alberta Children’s Hospital and University of Calgary, Calgary, Alberta; London Health Sciences Centre and Western University, London; the Children’s Hospital of Eastern Ontario and University of Ottawa, Ottawa, Ontario, Canada; the Shands Children’s Hospital and University of Florida, Gainesville, Florida, USA. Funded by a grant from the Canadian Initiative for Outcomes in Rheumatology Care, Canadian Rheumatology Association. The Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh-Out) cohort was funded by a New Emerging Team research grant from the Canadian Institutes of Health Research. Dr. Guzman was funded by a Clinical Investigator Award from the Child and Family Research Institute, Vancouver, British Columbia, Canada. J. Guzman, MD, MSc, British Columbia Children’s Hospital and the University of British Columbia; A. Henrey, PhD, Simon Fraser University; T. Loughin, PhD, Professor, Simon Fraser University; R.A. Berard, MD, MSc, London Health Sciences Centre and Western University; N.J. Shiff, MD, MSc, Shands Children’s Hospital and University of Florida; R. Jurencak, MD, Children’s Hospital of Eastern Ontario and University of Ottawa; S.M. Benseler, MD, PhD, Alberta Children’s Hospital and University of Calgary; L.B. Tucker, MD, British Columbia Children’s Hospital and the University of British Columbia. Address reprint requests to Dr. J. Guzman, Division of Pediatric Rheumatology, BC Children’s Hospital, 4500 Oak St., Suite K4-122, Vancouver, British Columbia V6H 3N1, Canada. E-mail: jguzman@cw.bc.ca. Accepted for publication October 25, 2016.
Susanne M. Benseler
From the British Columbia Children’s Hospital and the University of British Columbia, Vancouver; Simon Fraser University, Burnaby, British Columbia; the Alberta Children’s Hospital and University of Calgary, Calgary, Alberta; London Health Sciences Centre and Western University, London; the Children’s Hospital of Eastern Ontario and University of Ottawa, Ottawa, Ontario, Canada; the Shands Children’s Hospital and University of Florida, Gainesville, Florida, USA. Funded by a grant from the Canadian Initiative for Outcomes in Rheumatology Care, Canadian Rheumatology Association. The Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh-Out) cohort was funded by a New Emerging Team research grant from the Canadian Institutes of Health Research. Dr. Guzman was funded by a Clinical Investigator Award from the Child and Family Research Institute, Vancouver, British Columbia, Canada. J. Guzman, MD, MSc, British Columbia Children’s Hospital and the University of British Columbia; A. Henrey, PhD, Simon Fraser University; T. Loughin, PhD, Professor, Simon Fraser University; R.A. Berard, MD, MSc, London Health Sciences Centre and Western University; N.J. Shiff, MD, MSc, Shands Children’s Hospital and University of Florida; R. Jurencak, MD, Children’s Hospital of Eastern Ontario and University of Ottawa; S.M. Benseler, MD, PhD, Alberta Children’s Hospital and University of Calgary; L.B. Tucker, MD, British Columbia Children’s Hospital and the University of British Columbia. Address reprint requests to Dr. J. Guzman, Division of Pediatric Rheumatology, BC Children’s Hospital, 4500 Oak St., Suite K4-122, Vancouver, British Columbia V6H 3N1, Canada. E-mail: jguzman@cw.bc.ca. Accepted for publication October 25, 2016.
Lori B. Tucker
From the British Columbia Children’s Hospital and the University of British Columbia, Vancouver; Simon Fraser University, Burnaby, British Columbia; the Alberta Children’s Hospital and University of Calgary, Calgary, Alberta; London Health Sciences Centre and Western University, London; the Children’s Hospital of Eastern Ontario and University of Ottawa, Ottawa, Ontario, Canada; the Shands Children’s Hospital and University of Florida, Gainesville, Florida, USA. Funded by a grant from the Canadian Initiative for Outcomes in Rheumatology Care, Canadian Rheumatology Association. The Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh-Out) cohort was funded by a New Emerging Team research grant from the Canadian Institutes of Health Research. Dr. Guzman was funded by a Clinical Investigator Award from the Child and Family Research Institute, Vancouver, British Columbia, Canada. J. Guzman, MD, MSc, British Columbia Children’s Hospital and the University of British Columbia; A. Henrey, PhD, Simon Fraser University; T. Loughin, PhD, Professor, Simon Fraser University; R.A. Berard, MD, MSc, London Health Sciences Centre and Western University; N.J. Shiff, MD, MSc, Shands Children’s Hospital and University of Florida; R. Jurencak, MD, Children’s Hospital of Eastern Ontario and University of Ottawa; S.M. Benseler, MD, PhD, Alberta Children’s Hospital and University of Calgary; L.B. Tucker, MD, British Columbia Children’s Hospital and the University of British Columbia. Address reprint requests to Dr. J. Guzman, Division of Pediatric Rheumatology, BC Children’s Hospital, 4500 Oak St., Suite K4-122, Vancouver, British Columbia V6H 3N1, Canada. E-mail: jguzman@cw.bc.ca. Accepted for publication October 25, 2016.
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The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Predicting Which Children with Juvenile Idiopathic Arthritis Will Have a Severe Disease Course: Results from the ReACCh-Out Cohort
Jaime Guzman, Andrew Henrey, Thomas Loughin, Roberta A. Berard, Natalie J. Shiff, Roman Jurencak, Susanne M. Benseler, Lori B. Tucker
The Journal of Rheumatology Dec 2016, jrheum.160197; DOI: 10.3899/jrheum.160197
Predicting Which Children with Juvenile Idiopathic Arthritis Will Have a Severe Disease Course: Results from the ReACCh-Out Cohort
Jaime Guzman, Andrew Henrey, Thomas Loughin, Roberta A. Berard, Natalie J. Shiff, Roman Jurencak, Susanne M. Benseler, Lori B. Tucker
The Journal of Rheumatology Dec 2016, jrheum.160197; DOI: 10.3899/jrheum.160197