Research ArticleArticle
Proteomic Investigation of Dermal Fibroblasts Isolated from Affected and Unaffected Skin Samples from Patients with Limited Cutaneous Systemic Sclerosis: 2 Distinct Entities?
Claudio Corallo, Annalisa Santucci, Giulia Bernardini, Natale Figura, Roberto Leoncini, Giulia Riolo, Antonio Montella, Chiara Chirico, Ranuccio Nuti and Nicola Giordano
The Journal of Rheumatology December 2016, jrheum.160736; DOI: https://doi.org/10.3899/jrheum.160736
Claudio Corallo
From the Department of Medicine, Surgery, and Neurosciences; the Department of Biotechnology, Chemistry and Pharmacy; and the Department of Medical Biotechnology, University of Siena, Siena, Italy. C. Corallo, PhD, Department of Medicine, Surgery and Neurosciences, University of Siena; A. Santucci, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; G. Bernardini, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; N. Figura, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Leoncini, PhD, Department of Medical Biotechnology, University of Siena; G. Riolo, PhD, Department of Medical Biotechnology, University of Siena; A. Montella, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; C. Chirico, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Nuti, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; N. Giordano, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena. Address correspondence to C. Corallo, Scleroderma Unit, Department of Medicine, Surgery, and Neurosciences, University of Siena, 53100 Siena, Italy. E-mail: corallo.claudio@gmail.com. Accepted for publication October 18, 2016.
Annalisa Santucci
From the Department of Medicine, Surgery, and Neurosciences; the Department of Biotechnology, Chemistry and Pharmacy; and the Department of Medical Biotechnology, University of Siena, Siena, Italy. C. Corallo, PhD, Department of Medicine, Surgery and Neurosciences, University of Siena; A. Santucci, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; G. Bernardini, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; N. Figura, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Leoncini, PhD, Department of Medical Biotechnology, University of Siena; G. Riolo, PhD, Department of Medical Biotechnology, University of Siena; A. Montella, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; C. Chirico, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Nuti, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; N. Giordano, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena. Address correspondence to C. Corallo, Scleroderma Unit, Department of Medicine, Surgery, and Neurosciences, University of Siena, 53100 Siena, Italy. E-mail: corallo.claudio@gmail.com. Accepted for publication October 18, 2016.
Giulia Bernardini
From the Department of Medicine, Surgery, and Neurosciences; the Department of Biotechnology, Chemistry and Pharmacy; and the Department of Medical Biotechnology, University of Siena, Siena, Italy. C. Corallo, PhD, Department of Medicine, Surgery and Neurosciences, University of Siena; A. Santucci, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; G. Bernardini, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; N. Figura, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Leoncini, PhD, Department of Medical Biotechnology, University of Siena; G. Riolo, PhD, Department of Medical Biotechnology, University of Siena; A. Montella, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; C. Chirico, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Nuti, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; N. Giordano, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena. Address correspondence to C. Corallo, Scleroderma Unit, Department of Medicine, Surgery, and Neurosciences, University of Siena, 53100 Siena, Italy. E-mail: corallo.claudio@gmail.com. Accepted for publication October 18, 2016.
Natale Figura
From the Department of Medicine, Surgery, and Neurosciences; the Department of Biotechnology, Chemistry and Pharmacy; and the Department of Medical Biotechnology, University of Siena, Siena, Italy. C. Corallo, PhD, Department of Medicine, Surgery and Neurosciences, University of Siena; A. Santucci, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; G. Bernardini, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; N. Figura, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Leoncini, PhD, Department of Medical Biotechnology, University of Siena; G. Riolo, PhD, Department of Medical Biotechnology, University of Siena; A. Montella, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; C. Chirico, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Nuti, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; N. Giordano, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena. Address correspondence to C. Corallo, Scleroderma Unit, Department of Medicine, Surgery, and Neurosciences, University of Siena, 53100 Siena, Italy. E-mail: corallo.claudio@gmail.com. Accepted for publication October 18, 2016.
Roberto Leoncini
From the Department of Medicine, Surgery, and Neurosciences; the Department of Biotechnology, Chemistry and Pharmacy; and the Department of Medical Biotechnology, University of Siena, Siena, Italy. C. Corallo, PhD, Department of Medicine, Surgery and Neurosciences, University of Siena; A. Santucci, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; G. Bernardini, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; N. Figura, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Leoncini, PhD, Department of Medical Biotechnology, University of Siena; G. Riolo, PhD, Department of Medical Biotechnology, University of Siena; A. Montella, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; C. Chirico, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Nuti, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; N. Giordano, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena. Address correspondence to C. Corallo, Scleroderma Unit, Department of Medicine, Surgery, and Neurosciences, University of Siena, 53100 Siena, Italy. E-mail: corallo.claudio@gmail.com. Accepted for publication October 18, 2016.
Giulia Riolo
From the Department of Medicine, Surgery, and Neurosciences; the Department of Biotechnology, Chemistry and Pharmacy; and the Department of Medical Biotechnology, University of Siena, Siena, Italy. C. Corallo, PhD, Department of Medicine, Surgery and Neurosciences, University of Siena; A. Santucci, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; G. Bernardini, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; N. Figura, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Leoncini, PhD, Department of Medical Biotechnology, University of Siena; G. Riolo, PhD, Department of Medical Biotechnology, University of Siena; A. Montella, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; C. Chirico, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Nuti, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; N. Giordano, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena. Address correspondence to C. Corallo, Scleroderma Unit, Department of Medicine, Surgery, and Neurosciences, University of Siena, 53100 Siena, Italy. E-mail: corallo.claudio@gmail.com. Accepted for publication October 18, 2016.
Antonio Montella
From the Department of Medicine, Surgery, and Neurosciences; the Department of Biotechnology, Chemistry and Pharmacy; and the Department of Medical Biotechnology, University of Siena, Siena, Italy. C. Corallo, PhD, Department of Medicine, Surgery and Neurosciences, University of Siena; A. Santucci, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; G. Bernardini, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; N. Figura, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Leoncini, PhD, Department of Medical Biotechnology, University of Siena; G. Riolo, PhD, Department of Medical Biotechnology, University of Siena; A. Montella, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; C. Chirico, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Nuti, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; N. Giordano, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena. Address correspondence to C. Corallo, Scleroderma Unit, Department of Medicine, Surgery, and Neurosciences, University of Siena, 53100 Siena, Italy. E-mail: corallo.claudio@gmail.com. Accepted for publication October 18, 2016.
Chiara Chirico
From the Department of Medicine, Surgery, and Neurosciences; the Department of Biotechnology, Chemistry and Pharmacy; and the Department of Medical Biotechnology, University of Siena, Siena, Italy. C. Corallo, PhD, Department of Medicine, Surgery and Neurosciences, University of Siena; A. Santucci, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; G. Bernardini, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; N. Figura, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Leoncini, PhD, Department of Medical Biotechnology, University of Siena; G. Riolo, PhD, Department of Medical Biotechnology, University of Siena; A. Montella, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; C. Chirico, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Nuti, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; N. Giordano, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena. Address correspondence to C. Corallo, Scleroderma Unit, Department of Medicine, Surgery, and Neurosciences, University of Siena, 53100 Siena, Italy. E-mail: corallo.claudio@gmail.com. Accepted for publication October 18, 2016.
Ranuccio Nuti
From the Department of Medicine, Surgery, and Neurosciences; the Department of Biotechnology, Chemistry and Pharmacy; and the Department of Medical Biotechnology, University of Siena, Siena, Italy. C. Corallo, PhD, Department of Medicine, Surgery and Neurosciences, University of Siena; A. Santucci, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; G. Bernardini, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; N. Figura, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Leoncini, PhD, Department of Medical Biotechnology, University of Siena; G. Riolo, PhD, Department of Medical Biotechnology, University of Siena; A. Montella, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; C. Chirico, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Nuti, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; N. Giordano, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena. Address correspondence to C. Corallo, Scleroderma Unit, Department of Medicine, Surgery, and Neurosciences, University of Siena, 53100 Siena, Italy. E-mail: corallo.claudio@gmail.com. Accepted for publication October 18, 2016.
Nicola Giordano
From the Department of Medicine, Surgery, and Neurosciences; the Department of Biotechnology, Chemistry and Pharmacy; and the Department of Medical Biotechnology, University of Siena, Siena, Italy. C. Corallo, PhD, Department of Medicine, Surgery and Neurosciences, University of Siena; A. Santucci, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; G. Bernardini, PhD, Department of Biotechnology, Chemistry and Pharmacy, University of Siena; N. Figura, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Leoncini, PhD, Department of Medical Biotechnology, University of Siena; G. Riolo, PhD, Department of Medical Biotechnology, University of Siena; A. Montella, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; C. Chirico, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; R. Nuti, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena; N. Giordano, MD, Department of Medicine, Surgery, and Neurosciences, University of Siena. Address correspondence to C. Corallo, Scleroderma Unit, Department of Medicine, Surgery, and Neurosciences, University of Siena, 53100 Siena, Italy. E-mail: corallo.claudio@gmail.com. Accepted for publication October 18, 2016.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 3
1 Mar 2024
Proteomic Investigation of Dermal Fibroblasts Isolated from Affected and Unaffected Skin Samples from Patients with Limited Cutaneous Systemic Sclerosis: 2 Distinct Entities?
Claudio Corallo, Annalisa Santucci, Giulia Bernardini, Natale Figura, Roberto Leoncini, Giulia Riolo, Antonio Montella, Chiara Chirico, Ranuccio Nuti, Nicola Giordano
The Journal of Rheumatology Dec 2016, jrheum.160736; DOI: 10.3899/jrheum.160736
Proteomic Investigation of Dermal Fibroblasts Isolated from Affected and Unaffected Skin Samples from Patients with Limited Cutaneous Systemic Sclerosis: 2 Distinct Entities?
Claudio Corallo, Annalisa Santucci, Giulia Bernardini, Natale Figura, Roberto Leoncini, Giulia Riolo, Antonio Montella, Chiara Chirico, Ranuccio Nuti, Nicola Giordano
The Journal of Rheumatology Dec 2016, jrheum.160736; DOI: 10.3899/jrheum.160736