Research ArticleArticle
Developing a Risk-scoring Model for Ankylosing Spondylitis Based on a Combination of HLA-B27, Single-nucleotide Polymorphism, and Copy Number Variant Markers
Seung-Hyun Jung, Sung-Min Cho, Seon-Hee Yim, So-Hee Kim, Hyeon-Chun Park, Mi-La Cho, Seung-Cheol Shim, Tae-Hwan Kim, Sung-Hwan Park and Yeun-Jun Chung
The Journal of Rheumatology October 2016, jrheum.160347; DOI: https://doi.org/10.3899/jrheum.160347
Seung-Hyun Jung
From the Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea, College of Medicine; Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea, College of Medicine; Hanyang University Hospital for Rheumatic Diseases; Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul; Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, South Korea. Supported by a grant from the Korean Health Technology R&D Project, Ministry for Health and Welfare, Republic of Korea (HI14C3417). S.H. Jung, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.M. Cho, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Yim, MD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Kim, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; H.C. Park, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; M.L. Cho, PhD, Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea; S.C. Shim, MD, PhD, Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital; T.H. Kim, MD, PhD, Hanyang University Hospital for Rheumatic Diseases; S.H. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital; Y.J. Chung, MD, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea. Address correspondence to Dr. Y.J. Chung, Integrated Research Center for Genome Polymorphism, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Republic of Korea. E-mail: yejun@catholic.ac.kr. Accepted for publication August 16, 2016.
Sung-Min Cho
From the Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea, College of Medicine; Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea, College of Medicine; Hanyang University Hospital for Rheumatic Diseases; Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul; Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, South Korea. Supported by a grant from the Korean Health Technology R&D Project, Ministry for Health and Welfare, Republic of Korea (HI14C3417). S.H. Jung, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.M. Cho, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Yim, MD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Kim, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; H.C. Park, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; M.L. Cho, PhD, Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea; S.C. Shim, MD, PhD, Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital; T.H. Kim, MD, PhD, Hanyang University Hospital for Rheumatic Diseases; S.H. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital; Y.J. Chung, MD, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea. Address correspondence to Dr. Y.J. Chung, Integrated Research Center for Genome Polymorphism, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Republic of Korea. E-mail: yejun@catholic.ac.kr. Accepted for publication August 16, 2016.
Seon-Hee Yim
From the Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea, College of Medicine; Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea, College of Medicine; Hanyang University Hospital for Rheumatic Diseases; Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul; Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, South Korea. Supported by a grant from the Korean Health Technology R&D Project, Ministry for Health and Welfare, Republic of Korea (HI14C3417). S.H. Jung, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.M. Cho, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Yim, MD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Kim, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; H.C. Park, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; M.L. Cho, PhD, Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea; S.C. Shim, MD, PhD, Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital; T.H. Kim, MD, PhD, Hanyang University Hospital for Rheumatic Diseases; S.H. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital; Y.J. Chung, MD, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea. Address correspondence to Dr. Y.J. Chung, Integrated Research Center for Genome Polymorphism, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Republic of Korea. E-mail: yejun@catholic.ac.kr. Accepted for publication August 16, 2016.
So-Hee Kim
From the Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea, College of Medicine; Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea, College of Medicine; Hanyang University Hospital for Rheumatic Diseases; Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul; Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, South Korea. Supported by a grant from the Korean Health Technology R&D Project, Ministry for Health and Welfare, Republic of Korea (HI14C3417). S.H. Jung, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.M. Cho, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Yim, MD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Kim, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; H.C. Park, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; M.L. Cho, PhD, Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea; S.C. Shim, MD, PhD, Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital; T.H. Kim, MD, PhD, Hanyang University Hospital for Rheumatic Diseases; S.H. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital; Y.J. Chung, MD, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea. Address correspondence to Dr. Y.J. Chung, Integrated Research Center for Genome Polymorphism, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Republic of Korea. E-mail: yejun@catholic.ac.kr. Accepted for publication August 16, 2016.
Hyeon-Chun Park
From the Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea, College of Medicine; Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea, College of Medicine; Hanyang University Hospital for Rheumatic Diseases; Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul; Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, South Korea. Supported by a grant from the Korean Health Technology R&D Project, Ministry for Health and Welfare, Republic of Korea (HI14C3417). S.H. Jung, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.M. Cho, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Yim, MD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Kim, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; H.C. Park, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; M.L. Cho, PhD, Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea; S.C. Shim, MD, PhD, Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital; T.H. Kim, MD, PhD, Hanyang University Hospital for Rheumatic Diseases; S.H. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital; Y.J. Chung, MD, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea. Address correspondence to Dr. Y.J. Chung, Integrated Research Center for Genome Polymorphism, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Republic of Korea. E-mail: yejun@catholic.ac.kr. Accepted for publication August 16, 2016.
Mi-La Cho
From the Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea, College of Medicine; Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea, College of Medicine; Hanyang University Hospital for Rheumatic Diseases; Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul; Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, South Korea. Supported by a grant from the Korean Health Technology R&D Project, Ministry for Health and Welfare, Republic of Korea (HI14C3417). S.H. Jung, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.M. Cho, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Yim, MD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Kim, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; H.C. Park, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; M.L. Cho, PhD, Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea; S.C. Shim, MD, PhD, Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital; T.H. Kim, MD, PhD, Hanyang University Hospital for Rheumatic Diseases; S.H. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital; Y.J. Chung, MD, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea. Address correspondence to Dr. Y.J. Chung, Integrated Research Center for Genome Polymorphism, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Republic of Korea. E-mail: yejun@catholic.ac.kr. Accepted for publication August 16, 2016.
Seung-Cheol Shim
From the Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea, College of Medicine; Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea, College of Medicine; Hanyang University Hospital for Rheumatic Diseases; Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul; Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, South Korea. Supported by a grant from the Korean Health Technology R&D Project, Ministry for Health and Welfare, Republic of Korea (HI14C3417). S.H. Jung, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.M. Cho, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Yim, MD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Kim, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; H.C. Park, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; M.L. Cho, PhD, Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea; S.C. Shim, MD, PhD, Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital; T.H. Kim, MD, PhD, Hanyang University Hospital for Rheumatic Diseases; S.H. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital; Y.J. Chung, MD, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea. Address correspondence to Dr. Y.J. Chung, Integrated Research Center for Genome Polymorphism, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Republic of Korea. E-mail: yejun@catholic.ac.kr. Accepted for publication August 16, 2016.
Tae-Hwan Kim
From the Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea, College of Medicine; Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea, College of Medicine; Hanyang University Hospital for Rheumatic Diseases; Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul; Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, South Korea. Supported by a grant from the Korean Health Technology R&D Project, Ministry for Health and Welfare, Republic of Korea (HI14C3417). S.H. Jung, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.M. Cho, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Yim, MD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Kim, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; H.C. Park, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; M.L. Cho, PhD, Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea; S.C. Shim, MD, PhD, Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital; T.H. Kim, MD, PhD, Hanyang University Hospital for Rheumatic Diseases; S.H. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital; Y.J. Chung, MD, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea. Address correspondence to Dr. Y.J. Chung, Integrated Research Center for Genome Polymorphism, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Republic of Korea. E-mail: yejun@catholic.ac.kr. Accepted for publication August 16, 2016.
Sung-Hwan Park
From the Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea, College of Medicine; Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea, College of Medicine; Hanyang University Hospital for Rheumatic Diseases; Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul; Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, South Korea. Supported by a grant from the Korean Health Technology R&D Project, Ministry for Health and Welfare, Republic of Korea (HI14C3417). S.H. Jung, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.M. Cho, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Yim, MD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Kim, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; H.C. Park, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; M.L. Cho, PhD, Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea; S.C. Shim, MD, PhD, Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital; T.H. Kim, MD, PhD, Hanyang University Hospital for Rheumatic Diseases; S.H. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital; Y.J. Chung, MD, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea. Address correspondence to Dr. Y.J. Chung, Integrated Research Center for Genome Polymorphism, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Republic of Korea. E-mail: yejun@catholic.ac.kr. Accepted for publication August 16, 2016.
Yeun-Jun Chung
From the Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea, College of Medicine; Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea, College of Medicine; Hanyang University Hospital for Rheumatic Diseases; Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul; Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, South Korea. Supported by a grant from the Korean Health Technology R&D Project, Ministry for Health and Welfare, Republic of Korea (HI14C3417). S.H. Jung, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.M. Cho, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Yim, MD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Kim, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; H.C. Park, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; M.L. Cho, PhD, Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea; S.C. Shim, MD, PhD, Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital; T.H. Kim, MD, PhD, Hanyang University Hospital for Rheumatic Diseases; S.H. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital; Y.J. Chung, MD, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea. Address correspondence to Dr. Y.J. Chung, Integrated Research Center for Genome Polymorphism, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Republic of Korea. E-mail: yejun@catholic.ac.kr. Accepted for publication August 16, 2016.
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- Published online October 1, 2016.
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© 2016 The Journal of Rheumatology
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- Seung-Hyun Jung,
- Sung-Min Cho,
- Seon-Hee Yim,
- So-Hee Kim,
- Hyeon-Chun Park,
- Mi-La Cho,
- Seung-Cheol Shim,
- Tae-Hwan Kim,
- Sung-Hwan Park and
- Yeun-Jun Chung
- From the Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea, College of Medicine; Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea, College of Medicine; Hanyang University Hospital for Rheumatic Diseases; Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul; Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, South Korea.
Supported by a grant from the Korean Health Technology R&D Project, Ministry for Health and Welfare, Republic of Korea (HI14C3417).
S.H. Jung, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.M. Cho, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Yim, MD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; S.H. Kim, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; H.C. Park, MS, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea; M.L. Cho, PhD, Rheumatism Research Center, Catholic Research Institutes of Medical Science, The Catholic University of Korea; S.C. Shim, MD, PhD, Division of Rheumatology, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital; T.H. Kim, MD, PhD, Hanyang University Hospital for Rheumatic Diseases; S.H. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital; Y.J. Chung, MD, PhD, Integrated Research Center for Genome Polymorphism, Department of Microbiology, The Catholic University of Korea.
Address correspondence to Dr. Y.J. Chung, Integrated Research Center for Genome Polymorphism, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Republic of Korea. E-mail: yejun@catholic.ac.kr.
Accepted for publication August 16, 2016.
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The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Developing a Risk-scoring Model for Ankylosing Spondylitis Based on a Combination of HLA-B27, Single-nucleotide Polymorphism, and Copy Number Variant Markers
Seung-Hyun Jung, Sung-Min Cho, Seon-Hee Yim, So-Hee Kim, Hyeon-Chun Park, Mi-La Cho, Seung-Cheol Shim, Tae-Hwan Kim, Sung-Hwan Park, Yeun-Jun Chung
The Journal of Rheumatology Oct 2016, jrheum.160347; DOI: 10.3899/jrheum.160347
Developing a Risk-scoring Model for Ankylosing Spondylitis Based on a Combination of HLA-B27, Single-nucleotide Polymorphism, and Copy Number Variant Markers
Seung-Hyun Jung, Sung-Min Cho, Seon-Hee Yim, So-Hee Kim, Hyeon-Chun Park, Mi-La Cho, Seung-Cheol Shim, Tae-Hwan Kim, Sung-Hwan Park, Yeun-Jun Chung
The Journal of Rheumatology Oct 2016, jrheum.160347; DOI: 10.3899/jrheum.160347