Research ArticleArticle
Effect of Adherence to Protocolized Targeted Intensifications of Disease-modifying Antirheumatic Drugs on Treatment Outcomes in Rheumatoid Arthritis: Results from an Australian Early Arthritis Cohort
Nasir T. Wabe, Michael J. Sorich, Mihir D. Wechalekar, Leslie G. Cleland, Leah McWilliams, Anita T.Y. Lee, Llewellyn D. Spargo, Robert G. Metcalf, Cindy Hall, Susanna M. Proudman and Michael D. Wiese
The Journal of Rheumatology July 2016, jrheum.151392; DOI: https://doi.org/10.3899/jrheum.151392
Nasir T. Wabe
From the School of Pharmacy and Medical Sciences, University of South Australia; Sansom Institute for Health Research, University of South Australia; School of Medicine, Flinders University; Department of Rheumatology, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide, Australia. N.T. Wabe, MPharm, MSc, PhD candidate, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research; M.J. Sorich, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, and School of Medicine, Flinders University; M.D. Wechalekar, MBBS, MD, FRACP, School of Medicine, Flinders University; L.G. Cleland, PhD, Professor, Department of Rheumatology, Royal Adelaide Hospital; L. McWilliams, BN, Associate Clinical Services Coordinator, Department of Rheumatology, Royal Adelaide Hospital; A.T. Lee, MBBS (Hons), FRACP, PhD, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; L.D. Spargo, BSc (Hons), Department of Rheumatology, Royal Adelaide Hospital; R.G. Metcalf, PhD, Department of Rheumatology, Royal Adelaide Hospital; C. Hall, Department of Rheumatology, Royal Adelaide Hospital; S.M. Proudman, MBBS (Hons), FRACP, Associate Professor, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; M.D. Wiese, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, University of South Australia. Address correspondence to N.T. Wabe, University of South Australia, School of Pharmacy and Medical Sciences, GPO Box 2471, Adelaide 5001, Australia. E-mail: wabnt001@mymail.unisa.edu.au. Accepted for publication May 27, 2016.
Michael J. Sorich
From the School of Pharmacy and Medical Sciences, University of South Australia; Sansom Institute for Health Research, University of South Australia; School of Medicine, Flinders University; Department of Rheumatology, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide, Australia. N.T. Wabe, MPharm, MSc, PhD candidate, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research; M.J. Sorich, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, and School of Medicine, Flinders University; M.D. Wechalekar, MBBS, MD, FRACP, School of Medicine, Flinders University; L.G. Cleland, PhD, Professor, Department of Rheumatology, Royal Adelaide Hospital; L. McWilliams, BN, Associate Clinical Services Coordinator, Department of Rheumatology, Royal Adelaide Hospital; A.T. Lee, MBBS (Hons), FRACP, PhD, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; L.D. Spargo, BSc (Hons), Department of Rheumatology, Royal Adelaide Hospital; R.G. Metcalf, PhD, Department of Rheumatology, Royal Adelaide Hospital; C. Hall, Department of Rheumatology, Royal Adelaide Hospital; S.M. Proudman, MBBS (Hons), FRACP, Associate Professor, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; M.D. Wiese, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, University of South Australia. Address correspondence to N.T. Wabe, University of South Australia, School of Pharmacy and Medical Sciences, GPO Box 2471, Adelaide 5001, Australia. E-mail: wabnt001@mymail.unisa.edu.au. Accepted for publication May 27, 2016.
Mihir D. Wechalekar
From the School of Pharmacy and Medical Sciences, University of South Australia; Sansom Institute for Health Research, University of South Australia; School of Medicine, Flinders University; Department of Rheumatology, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide, Australia. N.T. Wabe, MPharm, MSc, PhD candidate, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research; M.J. Sorich, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, and School of Medicine, Flinders University; M.D. Wechalekar, MBBS, MD, FRACP, School of Medicine, Flinders University; L.G. Cleland, PhD, Professor, Department of Rheumatology, Royal Adelaide Hospital; L. McWilliams, BN, Associate Clinical Services Coordinator, Department of Rheumatology, Royal Adelaide Hospital; A.T. Lee, MBBS (Hons), FRACP, PhD, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; L.D. Spargo, BSc (Hons), Department of Rheumatology, Royal Adelaide Hospital; R.G. Metcalf, PhD, Department of Rheumatology, Royal Adelaide Hospital; C. Hall, Department of Rheumatology, Royal Adelaide Hospital; S.M. Proudman, MBBS (Hons), FRACP, Associate Professor, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; M.D. Wiese, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, University of South Australia. Address correspondence to N.T. Wabe, University of South Australia, School of Pharmacy and Medical Sciences, GPO Box 2471, Adelaide 5001, Australia. E-mail: wabnt001@mymail.unisa.edu.au. Accepted for publication May 27, 2016.
Leslie G. Cleland
From the School of Pharmacy and Medical Sciences, University of South Australia; Sansom Institute for Health Research, University of South Australia; School of Medicine, Flinders University; Department of Rheumatology, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide, Australia. N.T. Wabe, MPharm, MSc, PhD candidate, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research; M.J. Sorich, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, and School of Medicine, Flinders University; M.D. Wechalekar, MBBS, MD, FRACP, School of Medicine, Flinders University; L.G. Cleland, PhD, Professor, Department of Rheumatology, Royal Adelaide Hospital; L. McWilliams, BN, Associate Clinical Services Coordinator, Department of Rheumatology, Royal Adelaide Hospital; A.T. Lee, MBBS (Hons), FRACP, PhD, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; L.D. Spargo, BSc (Hons), Department of Rheumatology, Royal Adelaide Hospital; R.G. Metcalf, PhD, Department of Rheumatology, Royal Adelaide Hospital; C. Hall, Department of Rheumatology, Royal Adelaide Hospital; S.M. Proudman, MBBS (Hons), FRACP, Associate Professor, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; M.D. Wiese, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, University of South Australia. Address correspondence to N.T. Wabe, University of South Australia, School of Pharmacy and Medical Sciences, GPO Box 2471, Adelaide 5001, Australia. E-mail: wabnt001@mymail.unisa.edu.au. Accepted for publication May 27, 2016.
Leah McWilliams
From the School of Pharmacy and Medical Sciences, University of South Australia; Sansom Institute for Health Research, University of South Australia; School of Medicine, Flinders University; Department of Rheumatology, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide, Australia. N.T. Wabe, MPharm, MSc, PhD candidate, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research; M.J. Sorich, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, and School of Medicine, Flinders University; M.D. Wechalekar, MBBS, MD, FRACP, School of Medicine, Flinders University; L.G. Cleland, PhD, Professor, Department of Rheumatology, Royal Adelaide Hospital; L. McWilliams, BN, Associate Clinical Services Coordinator, Department of Rheumatology, Royal Adelaide Hospital; A.T. Lee, MBBS (Hons), FRACP, PhD, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; L.D. Spargo, BSc (Hons), Department of Rheumatology, Royal Adelaide Hospital; R.G. Metcalf, PhD, Department of Rheumatology, Royal Adelaide Hospital; C. Hall, Department of Rheumatology, Royal Adelaide Hospital; S.M. Proudman, MBBS (Hons), FRACP, Associate Professor, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; M.D. Wiese, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, University of South Australia. Address correspondence to N.T. Wabe, University of South Australia, School of Pharmacy and Medical Sciences, GPO Box 2471, Adelaide 5001, Australia. E-mail: wabnt001@mymail.unisa.edu.au. Accepted for publication May 27, 2016.
Anita T.Y. Lee
From the School of Pharmacy and Medical Sciences, University of South Australia; Sansom Institute for Health Research, University of South Australia; School of Medicine, Flinders University; Department of Rheumatology, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide, Australia. N.T. Wabe, MPharm, MSc, PhD candidate, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research; M.J. Sorich, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, and School of Medicine, Flinders University; M.D. Wechalekar, MBBS, MD, FRACP, School of Medicine, Flinders University; L.G. Cleland, PhD, Professor, Department of Rheumatology, Royal Adelaide Hospital; L. McWilliams, BN, Associate Clinical Services Coordinator, Department of Rheumatology, Royal Adelaide Hospital; A.T. Lee, MBBS (Hons), FRACP, PhD, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; L.D. Spargo, BSc (Hons), Department of Rheumatology, Royal Adelaide Hospital; R.G. Metcalf, PhD, Department of Rheumatology, Royal Adelaide Hospital; C. Hall, Department of Rheumatology, Royal Adelaide Hospital; S.M. Proudman, MBBS (Hons), FRACP, Associate Professor, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; M.D. Wiese, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, University of South Australia. Address correspondence to N.T. Wabe, University of South Australia, School of Pharmacy and Medical Sciences, GPO Box 2471, Adelaide 5001, Australia. E-mail: wabnt001@mymail.unisa.edu.au. Accepted for publication May 27, 2016.
Llewellyn D. Spargo
From the School of Pharmacy and Medical Sciences, University of South Australia; Sansom Institute for Health Research, University of South Australia; School of Medicine, Flinders University; Department of Rheumatology, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide, Australia. N.T. Wabe, MPharm, MSc, PhD candidate, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research; M.J. Sorich, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, and School of Medicine, Flinders University; M.D. Wechalekar, MBBS, MD, FRACP, School of Medicine, Flinders University; L.G. Cleland, PhD, Professor, Department of Rheumatology, Royal Adelaide Hospital; L. McWilliams, BN, Associate Clinical Services Coordinator, Department of Rheumatology, Royal Adelaide Hospital; A.T. Lee, MBBS (Hons), FRACP, PhD, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; L.D. Spargo, BSc (Hons), Department of Rheumatology, Royal Adelaide Hospital; R.G. Metcalf, PhD, Department of Rheumatology, Royal Adelaide Hospital; C. Hall, Department of Rheumatology, Royal Adelaide Hospital; S.M. Proudman, MBBS (Hons), FRACP, Associate Professor, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; M.D. Wiese, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, University of South Australia. Address correspondence to N.T. Wabe, University of South Australia, School of Pharmacy and Medical Sciences, GPO Box 2471, Adelaide 5001, Australia. E-mail: wabnt001@mymail.unisa.edu.au. Accepted for publication May 27, 2016.
Robert G. Metcalf
From the School of Pharmacy and Medical Sciences, University of South Australia; Sansom Institute for Health Research, University of South Australia; School of Medicine, Flinders University; Department of Rheumatology, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide, Australia. N.T. Wabe, MPharm, MSc, PhD candidate, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research; M.J. Sorich, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, and School of Medicine, Flinders University; M.D. Wechalekar, MBBS, MD, FRACP, School of Medicine, Flinders University; L.G. Cleland, PhD, Professor, Department of Rheumatology, Royal Adelaide Hospital; L. McWilliams, BN, Associate Clinical Services Coordinator, Department of Rheumatology, Royal Adelaide Hospital; A.T. Lee, MBBS (Hons), FRACP, PhD, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; L.D. Spargo, BSc (Hons), Department of Rheumatology, Royal Adelaide Hospital; R.G. Metcalf, PhD, Department of Rheumatology, Royal Adelaide Hospital; C. Hall, Department of Rheumatology, Royal Adelaide Hospital; S.M. Proudman, MBBS (Hons), FRACP, Associate Professor, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; M.D. Wiese, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, University of South Australia. Address correspondence to N.T. Wabe, University of South Australia, School of Pharmacy and Medical Sciences, GPO Box 2471, Adelaide 5001, Australia. E-mail: wabnt001@mymail.unisa.edu.au. Accepted for publication May 27, 2016.
Cindy Hall
From the School of Pharmacy and Medical Sciences, University of South Australia; Sansom Institute for Health Research, University of South Australia; School of Medicine, Flinders University; Department of Rheumatology, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide, Australia. N.T. Wabe, MPharm, MSc, PhD candidate, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research; M.J. Sorich, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, and School of Medicine, Flinders University; M.D. Wechalekar, MBBS, MD, FRACP, School of Medicine, Flinders University; L.G. Cleland, PhD, Professor, Department of Rheumatology, Royal Adelaide Hospital; L. McWilliams, BN, Associate Clinical Services Coordinator, Department of Rheumatology, Royal Adelaide Hospital; A.T. Lee, MBBS (Hons), FRACP, PhD, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; L.D. Spargo, BSc (Hons), Department of Rheumatology, Royal Adelaide Hospital; R.G. Metcalf, PhD, Department of Rheumatology, Royal Adelaide Hospital; C. Hall, Department of Rheumatology, Royal Adelaide Hospital; S.M. Proudman, MBBS (Hons), FRACP, Associate Professor, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; M.D. Wiese, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, University of South Australia. Address correspondence to N.T. Wabe, University of South Australia, School of Pharmacy and Medical Sciences, GPO Box 2471, Adelaide 5001, Australia. E-mail: wabnt001@mymail.unisa.edu.au. Accepted for publication May 27, 2016.
Susanna M. Proudman
From the School of Pharmacy and Medical Sciences, University of South Australia; Sansom Institute for Health Research, University of South Australia; School of Medicine, Flinders University; Department of Rheumatology, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide, Australia. N.T. Wabe, MPharm, MSc, PhD candidate, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research; M.J. Sorich, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, and School of Medicine, Flinders University; M.D. Wechalekar, MBBS, MD, FRACP, School of Medicine, Flinders University; L.G. Cleland, PhD, Professor, Department of Rheumatology, Royal Adelaide Hospital; L. McWilliams, BN, Associate Clinical Services Coordinator, Department of Rheumatology, Royal Adelaide Hospital; A.T. Lee, MBBS (Hons), FRACP, PhD, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; L.D. Spargo, BSc (Hons), Department of Rheumatology, Royal Adelaide Hospital; R.G. Metcalf, PhD, Department of Rheumatology, Royal Adelaide Hospital; C. Hall, Department of Rheumatology, Royal Adelaide Hospital; S.M. Proudman, MBBS (Hons), FRACP, Associate Professor, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; M.D. Wiese, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, University of South Australia. Address correspondence to N.T. Wabe, University of South Australia, School of Pharmacy and Medical Sciences, GPO Box 2471, Adelaide 5001, Australia. E-mail: wabnt001@mymail.unisa.edu.au. Accepted for publication May 27, 2016.
Michael D. Wiese
From the School of Pharmacy and Medical Sciences, University of South Australia; Sansom Institute for Health Research, University of South Australia; School of Medicine, Flinders University; Department of Rheumatology, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide, Australia. N.T. Wabe, MPharm, MSc, PhD candidate, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research; M.J. Sorich, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, and School of Medicine, Flinders University; M.D. Wechalekar, MBBS, MD, FRACP, School of Medicine, Flinders University; L.G. Cleland, PhD, Professor, Department of Rheumatology, Royal Adelaide Hospital; L. McWilliams, BN, Associate Clinical Services Coordinator, Department of Rheumatology, Royal Adelaide Hospital; A.T. Lee, MBBS (Hons), FRACP, PhD, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; L.D. Spargo, BSc (Hons), Department of Rheumatology, Royal Adelaide Hospital; R.G. Metcalf, PhD, Department of Rheumatology, Royal Adelaide Hospital; C. Hall, Department of Rheumatology, Royal Adelaide Hospital; S.M. Proudman, MBBS (Hons), FRACP, Associate Professor, Department of Rheumatology, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide; M.D. Wiese, PhD, Associate Professor, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, University of South Australia. Address correspondence to N.T. Wabe, University of South Australia, School of Pharmacy and Medical Sciences, GPO Box 2471, Adelaide 5001, Australia. E-mail: wabnt001@mymail.unisa.edu.au. Accepted for publication May 27, 2016.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Effect of Adherence to Protocolized Targeted Intensifications of Disease-modifying Antirheumatic Drugs on Treatment Outcomes in Rheumatoid Arthritis: Results from an Australian Early Arthritis Cohort
Nasir T. Wabe, Michael J. Sorich, Mihir D. Wechalekar, Leslie G. Cleland, Leah McWilliams, Anita T.Y. Lee, Llewellyn D. Spargo, Robert G. Metcalf, Cindy Hall, Susanna M. Proudman, Michael D. Wiese
The Journal of Rheumatology Jul 2016, jrheum.151392; DOI: 10.3899/jrheum.151392
Effect of Adherence to Protocolized Targeted Intensifications of Disease-modifying Antirheumatic Drugs on Treatment Outcomes in Rheumatoid Arthritis: Results from an Australian Early Arthritis Cohort
Nasir T. Wabe, Michael J. Sorich, Mihir D. Wechalekar, Leslie G. Cleland, Leah McWilliams, Anita T.Y. Lee, Llewellyn D. Spargo, Robert G. Metcalf, Cindy Hall, Susanna M. Proudman, Michael D. Wiese
The Journal of Rheumatology Jul 2016, jrheum.151392; DOI: 10.3899/jrheum.151392