Research ArticleArticle
Proposal for a Candidate Core Set of Fitness and Strength Tests for Patients with Childhood or Adult Idiopathic Inflammatory Myopathies
Djamilla K.D. van der Stap, Lisa G. Rider, Helene Alexanderson, Adam M. Huber, Bruno Gualano, Patrick Gordon, Janjaap van der Net, Pernille Mathiesen, Liam G. Johnson, Floranne C. Ernste, Brian M. Feldman, Kristin M. Houghton, Davinder Singh-Grewal, Abraham Garcia Kutzbach, Li Alemo Munters and Tim Takken
The Journal of Rheumatology November 2015, jrheum.150270; DOI: https://doi.org/10.3899/jrheum.150270
Djamilla K.D. van der Stap
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Lisa G. Rider
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Helene Alexanderson
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Adam M. Huber
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Bruno Gualano
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Patrick Gordon
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Janjaap van der Net
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Pernille Mathiesen
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Liam G. Johnson
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Floranne C. Ernste
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Brian M. Feldman
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Kristin M. Houghton
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Davinder Singh-Grewal
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Abraham Garcia Kutzbach
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Li Alemo Munters
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Tim Takken
From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala. Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health. D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht. Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl. Accepted for publication September 21, 2015.
Roles: on behalf of the International Myositis Assessment and Clinical Studies Group
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- Djamilla K.D. van der Stap,
- Lisa G. Rider,
- Helene Alexanderson,
- Adam M. Huber,
- Bruno Gualano,
- Patrick Gordon,
- Janjaap van der Net,
- Pernille Mathiesen,
- Liam G. Johnson,
- Floranne C. Ernste,
- Brian M. Feldman,
- Kristin M. Houghton,
- Davinder Singh-Grewal,
- Abraham Garcia Kutzbach,
- Li Alemo Munters and
- Tim Takken, on behalf of the International Myositis Assessment and Clinical Studies Group
- From the Faculty of Human Movement Sciences, Free University, Amsterdam; Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland; Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester, Rochester, Minnesota; Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurobiology, Care Science and Society; Division of Physical Therapy, Karolinska Institutet; Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden; Izaak Walton Killam (IWK) Health Centre and Dalhousie University, Halifax, Nova Scotia; Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto; British Columbia’s Children’s Hospital; University of British Columbia, Vancouver, British Columbia, Canada; University of Sao Paulo, Sao Paulo, Brazil; Department of Rheumatology, King’s College Hospital, London, UK; Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet, Copenhagen, Denmark; Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne; The Sydney Children’s Hospitals Network Randwick and Westmead Campuses; Department of Paediatrics, the University of Western Sydney, Sydney; School of Paediatrics and Child Health, the University of Sydney; Discipline of Child and Maternal Health, the University of New South Wales, New South Wales; John Hunter Children’s Hospital, Newcastle, Australia; School of Medicine, University Francisco Marroquin, Guatemala, Guatemala.
Supported in part by the Intramural Research Program of the National Institute of Environmental Health Sciences, US National Institutes of Health.
D.K. van der Stap, MSc, Faculty of Human Movement Sciences, Free University, and Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; L.G. Rider, MD, Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health; H. Alexanderson, PhD, Department of Neurobiology, Care Science and Society, and Division of Physical Therapy, Karolinska Institutet, and the Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital; A.M. Huber, MD, IWK Health Centre and Dalhousie University; B. Gualano, PhD, University of Sao Paulo; P. Gordon, PhD, Department of Rheumatology, King’s College Hospital; J. van der Net, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht; P. Mathiesen, PhD, Paediatric Rheumatology Clinic, Paediatric Department, Rigshospitalet; L.G. Johnson, PhD, ISEAL, College of Sport and Exercise Science, Victoria University, and the Florey Institute of Neuroscience and Mental Health, University of Melbourne; F.C. Ernste, MD, Department of Internal Medicine, Division of Rheumatology, Mayo Clinic in Rochester; B.M. Feldman, MD, Department of Pediatrics, and Department of Medicine, and the Institute of Health Policy, Management and Evaluation, University of Toronto, and Division of Rheumatology, The Hospital for Sick Children; K.M. Houghton, MD, British Columbia’s Children’s Hospital, and The University of British Columbia; D. Singh-Grewal, PhD, the Sydney Children’s Hospitals Network Randwick and Westmead Campuses, and School of Paediatrics and Child Health, University of Sydney, and Discipline of Child and Maternal Health, University of New South Wales, and Department of Paediatrics, University of Western Sydney, and John Hunter Children’s Hospital; A. Garcia Kutzbach, MD, Director of the Postgraduate Program of Rheumatology AGAR, and Professor of Medicine and History of Medicine, School of Medicine University Francisco Marroquin, and Member of the Executive Committee Hospital Herrera Llerandi Guatemala; L. Alemo Munters, PhD, Physical Therapy Clinic, Orthopedic/Rheumatology Unit, Karolinska University Hospital, and Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University; T. Takken, PhD, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht.
Address correspondence to Dr. T. Takken, Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, KB.02.056.0, P.O. Box 85090, 3508 AB Utrecht, the Netherlands. E-mail: t.takken@umcutrecht.nl.
Accepted for publication September 21, 2015.
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The Journal of Rheumatology
Vol. 51, Issue 3
1 Mar 2024
Proposal for a Candidate Core Set of Fitness and Strength Tests for Patients with Childhood or Adult Idiopathic Inflammatory Myopathies
Djamilla K.D. van der Stap, Lisa G. Rider, Helene Alexanderson, Adam M. Huber, Bruno Gualano, Patrick Gordon, Janjaap van der Net, Pernille Mathiesen, Liam G. Johnson, Floranne C. Ernste, Brian M. Feldman, Kristin M. Houghton, Davinder Singh-Grewal, Abraham Garcia Kutzbach, Li Alemo Munters, Tim Takken
The Journal of Rheumatology Nov 2015, jrheum.150270; DOI: 10.3899/jrheum.150270
Proposal for a Candidate Core Set of Fitness and Strength Tests for Patients with Childhood or Adult Idiopathic Inflammatory Myopathies
Djamilla K.D. van der Stap, Lisa G. Rider, Helene Alexanderson, Adam M. Huber, Bruno Gualano, Patrick Gordon, Janjaap van der Net, Pernille Mathiesen, Liam G. Johnson, Floranne C. Ernste, Brian M. Feldman, Kristin M. Houghton, Davinder Singh-Grewal, Abraham Garcia Kutzbach, Li Alemo Munters, Tim Takken
The Journal of Rheumatology Nov 2015, jrheum.150270; DOI: 10.3899/jrheum.150270