Research ArticleArticle
Open Access
Pregnancy Outcomes in Subjects Exposed to Certolizumab Pegol
Megan E.B. Clowse, Douglas C. Wolf, Frauke Förger, John J. Cush, Amanda Golembesky, Laura Shaughnessy, Dirk De Cuyper and Uma Mahadevan
The Journal of Rheumatology November 2015, jrheum.140189; DOI: https://doi.org/10.3899/jrheum.140189
Megan E.B. Clowse
From Duke University Medical Center, Durham; Union Chimique Belge (UCB) Pharma, Raleigh, North Carolina; Atlanta Gastroenterology Associates, Atlanta, Georgia; Baylor Research Institute and Baylor University Medical Center, Dallas, Texas; University of California San Francisco (UCSF) Center for Colitis and Crohn’s Disease, San Francisco, California, USA; Department of Rheumatology, Immunology and Allergology, Inselspital, University of Bern, Bern, Switzerland; UCB Pharma, Brussels, Belgium. Study and publication supported by UCB Pharma. UCB Pharma sponsored the study and the development of the manuscript, and approved the manuscript. Dr. Clowse has received consulting fees from UCB Pharma. Dr. Wolf has received consulting fees, research grants, and speaker fees from UCB Pharma. Dr. Förger has received consultant and speaker fees from UCB Pharma. Dr. Cush has received research grants from UCB Pharma. Drs. Golembesky, Shaughnessy, and De Cuyper are employees of UCB Pharma. Dr. Mahadevan has received consultant fees from UCB Pharma. M.E. Clowse, MD, Duke University Medical Center; D.C. Wolf, MD, Atlanta Gastroenterology Associates; F. Förger, MD, Department of Rheumatology and Immunology and Allergology, Inselspital, University of Bern; J.J. Cush, MD, Baylor Research Institute and Baylor University Medical Center; A. Golembesky, PhD, UCB Pharma; L. Shaughnessy, PhD, UCB Pharma; D. De Cuyper, MD, UCB Pharma; U. Mahadevan, MD, UCSF Center for Colitis and Crohn’s Disease. Address correspondence to Dr. M. Clowse, Duke University Medical Center 3535, Durham, North Carolina 27710, USA. E-mail: megan.clowse@duke.edu. Full Release Article. For details see Reprints/Permissions at jrheum.org Accepted for publication August 13, 2015.
Douglas C. Wolf
From Duke University Medical Center, Durham; Union Chimique Belge (UCB) Pharma, Raleigh, North Carolina; Atlanta Gastroenterology Associates, Atlanta, Georgia; Baylor Research Institute and Baylor University Medical Center, Dallas, Texas; University of California San Francisco (UCSF) Center for Colitis and Crohn’s Disease, San Francisco, California, USA; Department of Rheumatology, Immunology and Allergology, Inselspital, University of Bern, Bern, Switzerland; UCB Pharma, Brussels, Belgium. Study and publication supported by UCB Pharma. UCB Pharma sponsored the study and the development of the manuscript, and approved the manuscript. Dr. Clowse has received consulting fees from UCB Pharma. Dr. Wolf has received consulting fees, research grants, and speaker fees from UCB Pharma. Dr. Förger has received consultant and speaker fees from UCB Pharma. Dr. Cush has received research grants from UCB Pharma. Drs. Golembesky, Shaughnessy, and De Cuyper are employees of UCB Pharma. Dr. Mahadevan has received consultant fees from UCB Pharma. M.E. Clowse, MD, Duke University Medical Center; D.C. Wolf, MD, Atlanta Gastroenterology Associates; F. Förger, MD, Department of Rheumatology and Immunology and Allergology, Inselspital, University of Bern; J.J. Cush, MD, Baylor Research Institute and Baylor University Medical Center; A. Golembesky, PhD, UCB Pharma; L. Shaughnessy, PhD, UCB Pharma; D. De Cuyper, MD, UCB Pharma; U. Mahadevan, MD, UCSF Center for Colitis and Crohn’s Disease. Address correspondence to Dr. M. Clowse, Duke University Medical Center 3535, Durham, North Carolina 27710, USA. E-mail: megan.clowse@duke.edu. Full Release Article. For details see Reprints/Permissions at jrheum.org Accepted for publication August 13, 2015.
Frauke Förger
From Duke University Medical Center, Durham; Union Chimique Belge (UCB) Pharma, Raleigh, North Carolina; Atlanta Gastroenterology Associates, Atlanta, Georgia; Baylor Research Institute and Baylor University Medical Center, Dallas, Texas; University of California San Francisco (UCSF) Center for Colitis and Crohn’s Disease, San Francisco, California, USA; Department of Rheumatology, Immunology and Allergology, Inselspital, University of Bern, Bern, Switzerland; UCB Pharma, Brussels, Belgium. Study and publication supported by UCB Pharma. UCB Pharma sponsored the study and the development of the manuscript, and approved the manuscript. Dr. Clowse has received consulting fees from UCB Pharma. Dr. Wolf has received consulting fees, research grants, and speaker fees from UCB Pharma. Dr. Förger has received consultant and speaker fees from UCB Pharma. Dr. Cush has received research grants from UCB Pharma. Drs. Golembesky, Shaughnessy, and De Cuyper are employees of UCB Pharma. Dr. Mahadevan has received consultant fees from UCB Pharma. M.E. Clowse, MD, Duke University Medical Center; D.C. Wolf, MD, Atlanta Gastroenterology Associates; F. Förger, MD, Department of Rheumatology and Immunology and Allergology, Inselspital, University of Bern; J.J. Cush, MD, Baylor Research Institute and Baylor University Medical Center; A. Golembesky, PhD, UCB Pharma; L. Shaughnessy, PhD, UCB Pharma; D. De Cuyper, MD, UCB Pharma; U. Mahadevan, MD, UCSF Center for Colitis and Crohn’s Disease. Address correspondence to Dr. M. Clowse, Duke University Medical Center 3535, Durham, North Carolina 27710, USA. E-mail: megan.clowse@duke.edu. Full Release Article. For details see Reprints/Permissions at jrheum.org Accepted for publication August 13, 2015.
John J. Cush
From Duke University Medical Center, Durham; Union Chimique Belge (UCB) Pharma, Raleigh, North Carolina; Atlanta Gastroenterology Associates, Atlanta, Georgia; Baylor Research Institute and Baylor University Medical Center, Dallas, Texas; University of California San Francisco (UCSF) Center for Colitis and Crohn’s Disease, San Francisco, California, USA; Department of Rheumatology, Immunology and Allergology, Inselspital, University of Bern, Bern, Switzerland; UCB Pharma, Brussels, Belgium. Study and publication supported by UCB Pharma. UCB Pharma sponsored the study and the development of the manuscript, and approved the manuscript. Dr. Clowse has received consulting fees from UCB Pharma. Dr. Wolf has received consulting fees, research grants, and speaker fees from UCB Pharma. Dr. Förger has received consultant and speaker fees from UCB Pharma. Dr. Cush has received research grants from UCB Pharma. Drs. Golembesky, Shaughnessy, and De Cuyper are employees of UCB Pharma. Dr. Mahadevan has received consultant fees from UCB Pharma. M.E. Clowse, MD, Duke University Medical Center; D.C. Wolf, MD, Atlanta Gastroenterology Associates; F. Förger, MD, Department of Rheumatology and Immunology and Allergology, Inselspital, University of Bern; J.J. Cush, MD, Baylor Research Institute and Baylor University Medical Center; A. Golembesky, PhD, UCB Pharma; L. Shaughnessy, PhD, UCB Pharma; D. De Cuyper, MD, UCB Pharma; U. Mahadevan, MD, UCSF Center for Colitis and Crohn’s Disease. Address correspondence to Dr. M. Clowse, Duke University Medical Center 3535, Durham, North Carolina 27710, USA. E-mail: megan.clowse@duke.edu. Full Release Article. For details see Reprints/Permissions at jrheum.org Accepted for publication August 13, 2015.
Amanda Golembesky
From Duke University Medical Center, Durham; Union Chimique Belge (UCB) Pharma, Raleigh, North Carolina; Atlanta Gastroenterology Associates, Atlanta, Georgia; Baylor Research Institute and Baylor University Medical Center, Dallas, Texas; University of California San Francisco (UCSF) Center for Colitis and Crohn’s Disease, San Francisco, California, USA; Department of Rheumatology, Immunology and Allergology, Inselspital, University of Bern, Bern, Switzerland; UCB Pharma, Brussels, Belgium. Study and publication supported by UCB Pharma. UCB Pharma sponsored the study and the development of the manuscript, and approved the manuscript. Dr. Clowse has received consulting fees from UCB Pharma. Dr. Wolf has received consulting fees, research grants, and speaker fees from UCB Pharma. Dr. Förger has received consultant and speaker fees from UCB Pharma. Dr. Cush has received research grants from UCB Pharma. Drs. Golembesky, Shaughnessy, and De Cuyper are employees of UCB Pharma. Dr. Mahadevan has received consultant fees from UCB Pharma. M.E. Clowse, MD, Duke University Medical Center; D.C. Wolf, MD, Atlanta Gastroenterology Associates; F. Förger, MD, Department of Rheumatology and Immunology and Allergology, Inselspital, University of Bern; J.J. Cush, MD, Baylor Research Institute and Baylor University Medical Center; A. Golembesky, PhD, UCB Pharma; L. Shaughnessy, PhD, UCB Pharma; D. De Cuyper, MD, UCB Pharma; U. Mahadevan, MD, UCSF Center for Colitis and Crohn’s Disease. Address correspondence to Dr. M. Clowse, Duke University Medical Center 3535, Durham, North Carolina 27710, USA. E-mail: megan.clowse@duke.edu. Full Release Article. For details see Reprints/Permissions at jrheum.org Accepted for publication August 13, 2015.
Laura Shaughnessy
From Duke University Medical Center, Durham; Union Chimique Belge (UCB) Pharma, Raleigh, North Carolina; Atlanta Gastroenterology Associates, Atlanta, Georgia; Baylor Research Institute and Baylor University Medical Center, Dallas, Texas; University of California San Francisco (UCSF) Center for Colitis and Crohn’s Disease, San Francisco, California, USA; Department of Rheumatology, Immunology and Allergology, Inselspital, University of Bern, Bern, Switzerland; UCB Pharma, Brussels, Belgium. Study and publication supported by UCB Pharma. UCB Pharma sponsored the study and the development of the manuscript, and approved the manuscript. Dr. Clowse has received consulting fees from UCB Pharma. Dr. Wolf has received consulting fees, research grants, and speaker fees from UCB Pharma. Dr. Förger has received consultant and speaker fees from UCB Pharma. Dr. Cush has received research grants from UCB Pharma. Drs. Golembesky, Shaughnessy, and De Cuyper are employees of UCB Pharma. Dr. Mahadevan has received consultant fees from UCB Pharma. M.E. Clowse, MD, Duke University Medical Center; D.C. Wolf, MD, Atlanta Gastroenterology Associates; F. Förger, MD, Department of Rheumatology and Immunology and Allergology, Inselspital, University of Bern; J.J. Cush, MD, Baylor Research Institute and Baylor University Medical Center; A. Golembesky, PhD, UCB Pharma; L. Shaughnessy, PhD, UCB Pharma; D. De Cuyper, MD, UCB Pharma; U. Mahadevan, MD, UCSF Center for Colitis and Crohn’s Disease. Address correspondence to Dr. M. Clowse, Duke University Medical Center 3535, Durham, North Carolina 27710, USA. E-mail: megan.clowse@duke.edu. Full Release Article. For details see Reprints/Permissions at jrheum.org Accepted for publication August 13, 2015.
Dirk De Cuyper
From Duke University Medical Center, Durham; Union Chimique Belge (UCB) Pharma, Raleigh, North Carolina; Atlanta Gastroenterology Associates, Atlanta, Georgia; Baylor Research Institute and Baylor University Medical Center, Dallas, Texas; University of California San Francisco (UCSF) Center for Colitis and Crohn’s Disease, San Francisco, California, USA; Department of Rheumatology, Immunology and Allergology, Inselspital, University of Bern, Bern, Switzerland; UCB Pharma, Brussels, Belgium. Study and publication supported by UCB Pharma. UCB Pharma sponsored the study and the development of the manuscript, and approved the manuscript. Dr. Clowse has received consulting fees from UCB Pharma. Dr. Wolf has received consulting fees, research grants, and speaker fees from UCB Pharma. Dr. Förger has received consultant and speaker fees from UCB Pharma. Dr. Cush has received research grants from UCB Pharma. Drs. Golembesky, Shaughnessy, and De Cuyper are employees of UCB Pharma. Dr. Mahadevan has received consultant fees from UCB Pharma. M.E. Clowse, MD, Duke University Medical Center; D.C. Wolf, MD, Atlanta Gastroenterology Associates; F. Förger, MD, Department of Rheumatology and Immunology and Allergology, Inselspital, University of Bern; J.J. Cush, MD, Baylor Research Institute and Baylor University Medical Center; A. Golembesky, PhD, UCB Pharma; L. Shaughnessy, PhD, UCB Pharma; D. De Cuyper, MD, UCB Pharma; U. Mahadevan, MD, UCSF Center for Colitis and Crohn’s Disease. Address correspondence to Dr. M. Clowse, Duke University Medical Center 3535, Durham, North Carolina 27710, USA. E-mail: megan.clowse@duke.edu. Full Release Article. For details see Reprints/Permissions at jrheum.org Accepted for publication August 13, 2015.
Uma Mahadevan
From Duke University Medical Center, Durham; Union Chimique Belge (UCB) Pharma, Raleigh, North Carolina; Atlanta Gastroenterology Associates, Atlanta, Georgia; Baylor Research Institute and Baylor University Medical Center, Dallas, Texas; University of California San Francisco (UCSF) Center for Colitis and Crohn’s Disease, San Francisco, California, USA; Department of Rheumatology, Immunology and Allergology, Inselspital, University of Bern, Bern, Switzerland; UCB Pharma, Brussels, Belgium. Study and publication supported by UCB Pharma. UCB Pharma sponsored the study and the development of the manuscript, and approved the manuscript. Dr. Clowse has received consulting fees from UCB Pharma. Dr. Wolf has received consulting fees, research grants, and speaker fees from UCB Pharma. Dr. Förger has received consultant and speaker fees from UCB Pharma. Dr. Cush has received research grants from UCB Pharma. Drs. Golembesky, Shaughnessy, and De Cuyper are employees of UCB Pharma. Dr. Mahadevan has received consultant fees from UCB Pharma. M.E. Clowse, MD, Duke University Medical Center; D.C. Wolf, MD, Atlanta Gastroenterology Associates; F. Förger, MD, Department of Rheumatology and Immunology and Allergology, Inselspital, University of Bern; J.J. Cush, MD, Baylor Research Institute and Baylor University Medical Center; A. Golembesky, PhD, UCB Pharma; L. Shaughnessy, PhD, UCB Pharma; D. De Cuyper, MD, UCB Pharma; U. Mahadevan, MD, UCSF Center for Colitis and Crohn’s Disease. Address correspondence to Dr. M. Clowse, Duke University Medical Center 3535, Durham, North Carolina 27710, USA. E-mail: megan.clowse@duke.edu. Full Release Article. For details see Reprints/Permissions at jrheum.org Accepted for publication August 13, 2015.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Pregnancy Outcomes in Subjects Exposed to Certolizumab Pegol
Megan E.B. Clowse, Douglas C. Wolf, Frauke Förger, John J. Cush, Amanda Golembesky, Laura Shaughnessy, Dirk De Cuyper, Uma Mahadevan
The Journal of Rheumatology Nov 2015, jrheum.140189; DOI: 10.3899/jrheum.140189