Research ArticleArticle
No Association between Daily Walking and Knee Structural Changes in People at Risk of or with Mild Knee Osteoarthritis. Prospective Data from the Multicenter Osteoarthritis Study
Britt Elin Øiestad, Emily Quinn, Daniel White, Frank Roemer, Ali Guermazi, Michael Nevitt, Neil A. Segal, Cora E. Lewis and David T. Felson
The Journal of Rheumatology June 2015, jrheum.150071; DOI: https://doi.org/10.3899/jrheum.150071
Britt Elin Øiestad
From the Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital, Oslo, Norway; Clinical Epidemiology Research and Training Unit, and Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts; Department of Epidemiology and Biostatistics, University of California, San Francisco, California; Department of Physical Therapy, University of Delaware, Newark, Delaware; Department of Rehabilitation Medicine, University of Kansas, Kansas City, Kansas; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA; Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany; Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, UK. Multicenter Osteoarthritis study funded by US National Institutes of Health and National Institute on Aging grants (AG18820, AG18832, AG18947, and AG19069). The Research Council of Norway funds a postdoctoral position for the corresponding author. B.E. Øiestad, PT, PhD, Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital; E. Quinn, MSc, Data Coordinating Center, Boston University School of Public Health; D. White, PT, ScD, MSc, Department of Physical Therapy, University of Delaware, and Clinical Epidemiology Research and Training Unit, Boston University School of Medicine; F. Roemer, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, and Department of Radiology, University of Erlangen-Nuremberg; A. Guermazi, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; M. Nevitt, PhD, Department of Epidemiology and Biostatistics, University of California; N.A. Segal, MD, MS, Department of Rehabilitation Medicine, University of Kansas; C.E. Lewis, MD, MSPH, Division of Preventive Medicine, University of Alabama at Birmingham; D.T. Felson, MD, MPH, Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, and Arthritis Research UK Epidemiology Unit, University of Manchester. Address correspondence to Dr. B.E. Øiestad, Oslo and Akershus University College of Applied Sciences, P.O. Box 4, St. Olavs plass, N-0130 Oslo, Norway. E-mail: Britt-Elin.Oiestad@hioa.no. Accepted for publication April 13, 2015.
Emily Quinn
From the Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital, Oslo, Norway; Clinical Epidemiology Research and Training Unit, and Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts; Department of Epidemiology and Biostatistics, University of California, San Francisco, California; Department of Physical Therapy, University of Delaware, Newark, Delaware; Department of Rehabilitation Medicine, University of Kansas, Kansas City, Kansas; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA; Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany; Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, UK. Multicenter Osteoarthritis study funded by US National Institutes of Health and National Institute on Aging grants (AG18820, AG18832, AG18947, and AG19069). The Research Council of Norway funds a postdoctoral position for the corresponding author. B.E. Øiestad, PT, PhD, Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital; E. Quinn, MSc, Data Coordinating Center, Boston University School of Public Health; D. White, PT, ScD, MSc, Department of Physical Therapy, University of Delaware, and Clinical Epidemiology Research and Training Unit, Boston University School of Medicine; F. Roemer, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, and Department of Radiology, University of Erlangen-Nuremberg; A. Guermazi, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; M. Nevitt, PhD, Department of Epidemiology and Biostatistics, University of California; N.A. Segal, MD, MS, Department of Rehabilitation Medicine, University of Kansas; C.E. Lewis, MD, MSPH, Division of Preventive Medicine, University of Alabama at Birmingham; D.T. Felson, MD, MPH, Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, and Arthritis Research UK Epidemiology Unit, University of Manchester. Address correspondence to Dr. B.E. Øiestad, Oslo and Akershus University College of Applied Sciences, P.O. Box 4, St. Olavs plass, N-0130 Oslo, Norway. E-mail: Britt-Elin.Oiestad@hioa.no. Accepted for publication April 13, 2015.
Daniel White
From the Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital, Oslo, Norway; Clinical Epidemiology Research and Training Unit, and Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts; Department of Epidemiology and Biostatistics, University of California, San Francisco, California; Department of Physical Therapy, University of Delaware, Newark, Delaware; Department of Rehabilitation Medicine, University of Kansas, Kansas City, Kansas; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA; Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany; Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, UK. Multicenter Osteoarthritis study funded by US National Institutes of Health and National Institute on Aging grants (AG18820, AG18832, AG18947, and AG19069). The Research Council of Norway funds a postdoctoral position for the corresponding author. B.E. Øiestad, PT, PhD, Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital; E. Quinn, MSc, Data Coordinating Center, Boston University School of Public Health; D. White, PT, ScD, MSc, Department of Physical Therapy, University of Delaware, and Clinical Epidemiology Research and Training Unit, Boston University School of Medicine; F. Roemer, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, and Department of Radiology, University of Erlangen-Nuremberg; A. Guermazi, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; M. Nevitt, PhD, Department of Epidemiology and Biostatistics, University of California; N.A. Segal, MD, MS, Department of Rehabilitation Medicine, University of Kansas; C.E. Lewis, MD, MSPH, Division of Preventive Medicine, University of Alabama at Birmingham; D.T. Felson, MD, MPH, Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, and Arthritis Research UK Epidemiology Unit, University of Manchester. Address correspondence to Dr. B.E. Øiestad, Oslo and Akershus University College of Applied Sciences, P.O. Box 4, St. Olavs plass, N-0130 Oslo, Norway. E-mail: Britt-Elin.Oiestad@hioa.no. Accepted for publication April 13, 2015.
Frank Roemer
From the Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital, Oslo, Norway; Clinical Epidemiology Research and Training Unit, and Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts; Department of Epidemiology and Biostatistics, University of California, San Francisco, California; Department of Physical Therapy, University of Delaware, Newark, Delaware; Department of Rehabilitation Medicine, University of Kansas, Kansas City, Kansas; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA; Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany; Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, UK. Multicenter Osteoarthritis study funded by US National Institutes of Health and National Institute on Aging grants (AG18820, AG18832, AG18947, and AG19069). The Research Council of Norway funds a postdoctoral position for the corresponding author. B.E. Øiestad, PT, PhD, Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital; E. Quinn, MSc, Data Coordinating Center, Boston University School of Public Health; D. White, PT, ScD, MSc, Department of Physical Therapy, University of Delaware, and Clinical Epidemiology Research and Training Unit, Boston University School of Medicine; F. Roemer, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, and Department of Radiology, University of Erlangen-Nuremberg; A. Guermazi, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; M. Nevitt, PhD, Department of Epidemiology and Biostatistics, University of California; N.A. Segal, MD, MS, Department of Rehabilitation Medicine, University of Kansas; C.E. Lewis, MD, MSPH, Division of Preventive Medicine, University of Alabama at Birmingham; D.T. Felson, MD, MPH, Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, and Arthritis Research UK Epidemiology Unit, University of Manchester. Address correspondence to Dr. B.E. Øiestad, Oslo and Akershus University College of Applied Sciences, P.O. Box 4, St. Olavs plass, N-0130 Oslo, Norway. E-mail: Britt-Elin.Oiestad@hioa.no. Accepted for publication April 13, 2015.
Ali Guermazi
From the Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital, Oslo, Norway; Clinical Epidemiology Research and Training Unit, and Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts; Department of Epidemiology and Biostatistics, University of California, San Francisco, California; Department of Physical Therapy, University of Delaware, Newark, Delaware; Department of Rehabilitation Medicine, University of Kansas, Kansas City, Kansas; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA; Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany; Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, UK. Multicenter Osteoarthritis study funded by US National Institutes of Health and National Institute on Aging grants (AG18820, AG18832, AG18947, and AG19069). The Research Council of Norway funds a postdoctoral position for the corresponding author. B.E. Øiestad, PT, PhD, Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital; E. Quinn, MSc, Data Coordinating Center, Boston University School of Public Health; D. White, PT, ScD, MSc, Department of Physical Therapy, University of Delaware, and Clinical Epidemiology Research and Training Unit, Boston University School of Medicine; F. Roemer, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, and Department of Radiology, University of Erlangen-Nuremberg; A. Guermazi, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; M. Nevitt, PhD, Department of Epidemiology and Biostatistics, University of California; N.A. Segal, MD, MS, Department of Rehabilitation Medicine, University of Kansas; C.E. Lewis, MD, MSPH, Division of Preventive Medicine, University of Alabama at Birmingham; D.T. Felson, MD, MPH, Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, and Arthritis Research UK Epidemiology Unit, University of Manchester. Address correspondence to Dr. B.E. Øiestad, Oslo and Akershus University College of Applied Sciences, P.O. Box 4, St. Olavs plass, N-0130 Oslo, Norway. E-mail: Britt-Elin.Oiestad@hioa.no. Accepted for publication April 13, 2015.
Michael Nevitt
From the Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital, Oslo, Norway; Clinical Epidemiology Research and Training Unit, and Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts; Department of Epidemiology and Biostatistics, University of California, San Francisco, California; Department of Physical Therapy, University of Delaware, Newark, Delaware; Department of Rehabilitation Medicine, University of Kansas, Kansas City, Kansas; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA; Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany; Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, UK. Multicenter Osteoarthritis study funded by US National Institutes of Health and National Institute on Aging grants (AG18820, AG18832, AG18947, and AG19069). The Research Council of Norway funds a postdoctoral position for the corresponding author. B.E. Øiestad, PT, PhD, Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital; E. Quinn, MSc, Data Coordinating Center, Boston University School of Public Health; D. White, PT, ScD, MSc, Department of Physical Therapy, University of Delaware, and Clinical Epidemiology Research and Training Unit, Boston University School of Medicine; F. Roemer, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, and Department of Radiology, University of Erlangen-Nuremberg; A. Guermazi, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; M. Nevitt, PhD, Department of Epidemiology and Biostatistics, University of California; N.A. Segal, MD, MS, Department of Rehabilitation Medicine, University of Kansas; C.E. Lewis, MD, MSPH, Division of Preventive Medicine, University of Alabama at Birmingham; D.T. Felson, MD, MPH, Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, and Arthritis Research UK Epidemiology Unit, University of Manchester. Address correspondence to Dr. B.E. Øiestad, Oslo and Akershus University College of Applied Sciences, P.O. Box 4, St. Olavs plass, N-0130 Oslo, Norway. E-mail: Britt-Elin.Oiestad@hioa.no. Accepted for publication April 13, 2015.
Neil A. Segal
From the Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital, Oslo, Norway; Clinical Epidemiology Research and Training Unit, and Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts; Department of Epidemiology and Biostatistics, University of California, San Francisco, California; Department of Physical Therapy, University of Delaware, Newark, Delaware; Department of Rehabilitation Medicine, University of Kansas, Kansas City, Kansas; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA; Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany; Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, UK. Multicenter Osteoarthritis study funded by US National Institutes of Health and National Institute on Aging grants (AG18820, AG18832, AG18947, and AG19069). The Research Council of Norway funds a postdoctoral position for the corresponding author. B.E. Øiestad, PT, PhD, Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital; E. Quinn, MSc, Data Coordinating Center, Boston University School of Public Health; D. White, PT, ScD, MSc, Department of Physical Therapy, University of Delaware, and Clinical Epidemiology Research and Training Unit, Boston University School of Medicine; F. Roemer, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, and Department of Radiology, University of Erlangen-Nuremberg; A. Guermazi, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; M. Nevitt, PhD, Department of Epidemiology and Biostatistics, University of California; N.A. Segal, MD, MS, Department of Rehabilitation Medicine, University of Kansas; C.E. Lewis, MD, MSPH, Division of Preventive Medicine, University of Alabama at Birmingham; D.T. Felson, MD, MPH, Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, and Arthritis Research UK Epidemiology Unit, University of Manchester. Address correspondence to Dr. B.E. Øiestad, Oslo and Akershus University College of Applied Sciences, P.O. Box 4, St. Olavs plass, N-0130 Oslo, Norway. E-mail: Britt-Elin.Oiestad@hioa.no. Accepted for publication April 13, 2015.
Cora E. Lewis
From the Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital, Oslo, Norway; Clinical Epidemiology Research and Training Unit, and Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts; Department of Epidemiology and Biostatistics, University of California, San Francisco, California; Department of Physical Therapy, University of Delaware, Newark, Delaware; Department of Rehabilitation Medicine, University of Kansas, Kansas City, Kansas; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA; Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany; Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, UK. Multicenter Osteoarthritis study funded by US National Institutes of Health and National Institute on Aging grants (AG18820, AG18832, AG18947, and AG19069). The Research Council of Norway funds a postdoctoral position for the corresponding author. B.E. Øiestad, PT, PhD, Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital; E. Quinn, MSc, Data Coordinating Center, Boston University School of Public Health; D. White, PT, ScD, MSc, Department of Physical Therapy, University of Delaware, and Clinical Epidemiology Research and Training Unit, Boston University School of Medicine; F. Roemer, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, and Department of Radiology, University of Erlangen-Nuremberg; A. Guermazi, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; M. Nevitt, PhD, Department of Epidemiology and Biostatistics, University of California; N.A. Segal, MD, MS, Department of Rehabilitation Medicine, University of Kansas; C.E. Lewis, MD, MSPH, Division of Preventive Medicine, University of Alabama at Birmingham; D.T. Felson, MD, MPH, Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, and Arthritis Research UK Epidemiology Unit, University of Manchester. Address correspondence to Dr. B.E. Øiestad, Oslo and Akershus University College of Applied Sciences, P.O. Box 4, St. Olavs plass, N-0130 Oslo, Norway. E-mail: Britt-Elin.Oiestad@hioa.no. Accepted for publication April 13, 2015.
David T. Felson
From the Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital, Oslo, Norway; Clinical Epidemiology Research and Training Unit, and Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts; Department of Epidemiology and Biostatistics, University of California, San Francisco, California; Department of Physical Therapy, University of Delaware, Newark, Delaware; Department of Rehabilitation Medicine, University of Kansas, Kansas City, Kansas; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA; Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany; Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, UK. Multicenter Osteoarthritis study funded by US National Institutes of Health and National Institute on Aging grants (AG18820, AG18832, AG18947, and AG19069). The Research Council of Norway funds a postdoctoral position for the corresponding author. B.E. Øiestad, PT, PhD, Norwegian Research Center for Active Rehabilitation, Department of Orthopedics, Oslo University Hospital; E. Quinn, MSc, Data Coordinating Center, Boston University School of Public Health; D. White, PT, ScD, MSc, Department of Physical Therapy, University of Delaware, and Clinical Epidemiology Research and Training Unit, Boston University School of Medicine; F. Roemer, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, and Department of Radiology, University of Erlangen-Nuremberg; A. Guermazi, MD, PhD, Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine; M. Nevitt, PhD, Department of Epidemiology and Biostatistics, University of California; N.A. Segal, MD, MS, Department of Rehabilitation Medicine, University of Kansas; C.E. Lewis, MD, MSPH, Division of Preventive Medicine, University of Alabama at Birmingham; D.T. Felson, MD, MPH, Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, and Arthritis Research UK Epidemiology Unit, University of Manchester. Address correspondence to Dr. B.E. Øiestad, Oslo and Akershus University College of Applied Sciences, P.O. Box 4, St. Olavs plass, N-0130 Oslo, Norway. E-mail: Britt-Elin.Oiestad@hioa.no. Accepted for publication April 13, 2015.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 3
1 Mar 2024
No Association between Daily Walking and Knee Structural Changes in People at Risk of or with Mild Knee Osteoarthritis. Prospective Data from the Multicenter Osteoarthritis Study
Britt Elin Øiestad, Emily Quinn, Daniel White, Frank Roemer, Ali Guermazi, Michael Nevitt, Neil A. Segal, Cora E. Lewis, David T. Felson
The Journal of Rheumatology Jun 2015, jrheum.150071; DOI: 10.3899/jrheum.150071
No Association between Daily Walking and Knee Structural Changes in People at Risk of or with Mild Knee Osteoarthritis. Prospective Data from the Multicenter Osteoarthritis Study
Britt Elin Øiestad, Emily Quinn, Daniel White, Frank Roemer, Ali Guermazi, Michael Nevitt, Neil A. Segal, Cora E. Lewis, David T. Felson
The Journal of Rheumatology Jun 2015, jrheum.150071; DOI: 10.3899/jrheum.150071