Research ArticleArticle
Effect of Urate-lowering Therapy on the Risk of Cardiovascular Disease and All-cause Mortality in Patients with Gout: A Case-matched Cohort Study
Jiunn-Horng Chen, Joung-Liang Lan, Chi-Fung Cheng, Wen-Miin Liang, Hsiao-Yi Lin, Gregory J. Tsay, Wen-Ting Yeh and Wen-Harn Pan
The Journal of Rheumatology June 2015, jrheum.141542; DOI: https://doi.org/10.3899/jrheum.141542
Jiunn-Horng Chen
From the School of Medicine, China Medical University, Section of Immunology and Rheumatology, Department of Internal Medicine, China Medical University Hospital; Department of Public Health, and Graduate Institute of Biostatistics, Biostatistics Center, China Medical University; Institute of Microbiology and Immunology, Chung-Shan Medical University, Taichung; School of Medicine, National Yang-Ming University, Section of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Veterans General Hospital; Institute of Biomedical Sciences, Academia Sinica, Taipei; Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan. Supported by grants from the Department of Health, Executive Yuan, Taiwan (NSC97-2314-B-039-010-MY3, NSC100-2314-B-039-012, NSC101-2314-B-039-020, MOST103-2314-B-039-020), and the China Medical University Hospital (DMR-101-010). J.H. Chen, MD, PhD, Associate Professor, China Medical University, China Medical University Hospital; J.L. Lan, MD, Professor, China Medical University, China Medical University Hospital; C.F. Cheng, MSc; W.M. Liang, PhD, Professor, China Medical University; H.Y. Lin, MD, Associate Professor, National Yang-Ming University, Veterans General Hospital; G.J. Tsay, MD, PhD, Professor, Chung-Shan Medical University; W.T. Yeh, MSc, Academia Sinica; W.H. Pan, PhD, Professor, Academia Sinica, National Health Research Institutes. Address correspondence to Dr. J.H. Chen, School of Medicine, China Medical University, No. 91 Hsueh-Shih Road, Taichung, Taiwan 40402. E-mail: d91842001@ntu.edu.tw. Accepted for publication April 20, 2015.
Joung-Liang Lan
From the School of Medicine, China Medical University, Section of Immunology and Rheumatology, Department of Internal Medicine, China Medical University Hospital; Department of Public Health, and Graduate Institute of Biostatistics, Biostatistics Center, China Medical University; Institute of Microbiology and Immunology, Chung-Shan Medical University, Taichung; School of Medicine, National Yang-Ming University, Section of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Veterans General Hospital; Institute of Biomedical Sciences, Academia Sinica, Taipei; Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan. Supported by grants from the Department of Health, Executive Yuan, Taiwan (NSC97-2314-B-039-010-MY3, NSC100-2314-B-039-012, NSC101-2314-B-039-020, MOST103-2314-B-039-020), and the China Medical University Hospital (DMR-101-010). J.H. Chen, MD, PhD, Associate Professor, China Medical University, China Medical University Hospital; J.L. Lan, MD, Professor, China Medical University, China Medical University Hospital; C.F. Cheng, MSc; W.M. Liang, PhD, Professor, China Medical University; H.Y. Lin, MD, Associate Professor, National Yang-Ming University, Veterans General Hospital; G.J. Tsay, MD, PhD, Professor, Chung-Shan Medical University; W.T. Yeh, MSc, Academia Sinica; W.H. Pan, PhD, Professor, Academia Sinica, National Health Research Institutes. Address correspondence to Dr. J.H. Chen, School of Medicine, China Medical University, No. 91 Hsueh-Shih Road, Taichung, Taiwan 40402. E-mail: d91842001@ntu.edu.tw. Accepted for publication April 20, 2015.
Chi-Fung Cheng
From the School of Medicine, China Medical University, Section of Immunology and Rheumatology, Department of Internal Medicine, China Medical University Hospital; Department of Public Health, and Graduate Institute of Biostatistics, Biostatistics Center, China Medical University; Institute of Microbiology and Immunology, Chung-Shan Medical University, Taichung; School of Medicine, National Yang-Ming University, Section of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Veterans General Hospital; Institute of Biomedical Sciences, Academia Sinica, Taipei; Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan. Supported by grants from the Department of Health, Executive Yuan, Taiwan (NSC97-2314-B-039-010-MY3, NSC100-2314-B-039-012, NSC101-2314-B-039-020, MOST103-2314-B-039-020), and the China Medical University Hospital (DMR-101-010). J.H. Chen, MD, PhD, Associate Professor, China Medical University, China Medical University Hospital; J.L. Lan, MD, Professor, China Medical University, China Medical University Hospital; C.F. Cheng, MSc; W.M. Liang, PhD, Professor, China Medical University; H.Y. Lin, MD, Associate Professor, National Yang-Ming University, Veterans General Hospital; G.J. Tsay, MD, PhD, Professor, Chung-Shan Medical University; W.T. Yeh, MSc, Academia Sinica; W.H. Pan, PhD, Professor, Academia Sinica, National Health Research Institutes. Address correspondence to Dr. J.H. Chen, School of Medicine, China Medical University, No. 91 Hsueh-Shih Road, Taichung, Taiwan 40402. E-mail: d91842001@ntu.edu.tw. Accepted for publication April 20, 2015.
Wen-Miin Liang
From the School of Medicine, China Medical University, Section of Immunology and Rheumatology, Department of Internal Medicine, China Medical University Hospital; Department of Public Health, and Graduate Institute of Biostatistics, Biostatistics Center, China Medical University; Institute of Microbiology and Immunology, Chung-Shan Medical University, Taichung; School of Medicine, National Yang-Ming University, Section of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Veterans General Hospital; Institute of Biomedical Sciences, Academia Sinica, Taipei; Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan. Supported by grants from the Department of Health, Executive Yuan, Taiwan (NSC97-2314-B-039-010-MY3, NSC100-2314-B-039-012, NSC101-2314-B-039-020, MOST103-2314-B-039-020), and the China Medical University Hospital (DMR-101-010). J.H. Chen, MD, PhD, Associate Professor, China Medical University, China Medical University Hospital; J.L. Lan, MD, Professor, China Medical University, China Medical University Hospital; C.F. Cheng, MSc; W.M. Liang, PhD, Professor, China Medical University; H.Y. Lin, MD, Associate Professor, National Yang-Ming University, Veterans General Hospital; G.J. Tsay, MD, PhD, Professor, Chung-Shan Medical University; W.T. Yeh, MSc, Academia Sinica; W.H. Pan, PhD, Professor, Academia Sinica, National Health Research Institutes. Address correspondence to Dr. J.H. Chen, School of Medicine, China Medical University, No. 91 Hsueh-Shih Road, Taichung, Taiwan 40402. E-mail: d91842001@ntu.edu.tw. Accepted for publication April 20, 2015.
Hsiao-Yi Lin
From the School of Medicine, China Medical University, Section of Immunology and Rheumatology, Department of Internal Medicine, China Medical University Hospital; Department of Public Health, and Graduate Institute of Biostatistics, Biostatistics Center, China Medical University; Institute of Microbiology and Immunology, Chung-Shan Medical University, Taichung; School of Medicine, National Yang-Ming University, Section of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Veterans General Hospital; Institute of Biomedical Sciences, Academia Sinica, Taipei; Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan. Supported by grants from the Department of Health, Executive Yuan, Taiwan (NSC97-2314-B-039-010-MY3, NSC100-2314-B-039-012, NSC101-2314-B-039-020, MOST103-2314-B-039-020), and the China Medical University Hospital (DMR-101-010). J.H. Chen, MD, PhD, Associate Professor, China Medical University, China Medical University Hospital; J.L. Lan, MD, Professor, China Medical University, China Medical University Hospital; C.F. Cheng, MSc; W.M. Liang, PhD, Professor, China Medical University; H.Y. Lin, MD, Associate Professor, National Yang-Ming University, Veterans General Hospital; G.J. Tsay, MD, PhD, Professor, Chung-Shan Medical University; W.T. Yeh, MSc, Academia Sinica; W.H. Pan, PhD, Professor, Academia Sinica, National Health Research Institutes. Address correspondence to Dr. J.H. Chen, School of Medicine, China Medical University, No. 91 Hsueh-Shih Road, Taichung, Taiwan 40402. E-mail: d91842001@ntu.edu.tw. Accepted for publication April 20, 2015.
Gregory J. Tsay
From the School of Medicine, China Medical University, Section of Immunology and Rheumatology, Department of Internal Medicine, China Medical University Hospital; Department of Public Health, and Graduate Institute of Biostatistics, Biostatistics Center, China Medical University; Institute of Microbiology and Immunology, Chung-Shan Medical University, Taichung; School of Medicine, National Yang-Ming University, Section of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Veterans General Hospital; Institute of Biomedical Sciences, Academia Sinica, Taipei; Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan. Supported by grants from the Department of Health, Executive Yuan, Taiwan (NSC97-2314-B-039-010-MY3, NSC100-2314-B-039-012, NSC101-2314-B-039-020, MOST103-2314-B-039-020), and the China Medical University Hospital (DMR-101-010). J.H. Chen, MD, PhD, Associate Professor, China Medical University, China Medical University Hospital; J.L. Lan, MD, Professor, China Medical University, China Medical University Hospital; C.F. Cheng, MSc; W.M. Liang, PhD, Professor, China Medical University; H.Y. Lin, MD, Associate Professor, National Yang-Ming University, Veterans General Hospital; G.J. Tsay, MD, PhD, Professor, Chung-Shan Medical University; W.T. Yeh, MSc, Academia Sinica; W.H. Pan, PhD, Professor, Academia Sinica, National Health Research Institutes. Address correspondence to Dr. J.H. Chen, School of Medicine, China Medical University, No. 91 Hsueh-Shih Road, Taichung, Taiwan 40402. E-mail: d91842001@ntu.edu.tw. Accepted for publication April 20, 2015.
Wen-Ting Yeh
From the School of Medicine, China Medical University, Section of Immunology and Rheumatology, Department of Internal Medicine, China Medical University Hospital; Department of Public Health, and Graduate Institute of Biostatistics, Biostatistics Center, China Medical University; Institute of Microbiology and Immunology, Chung-Shan Medical University, Taichung; School of Medicine, National Yang-Ming University, Section of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Veterans General Hospital; Institute of Biomedical Sciences, Academia Sinica, Taipei; Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan. Supported by grants from the Department of Health, Executive Yuan, Taiwan (NSC97-2314-B-039-010-MY3, NSC100-2314-B-039-012, NSC101-2314-B-039-020, MOST103-2314-B-039-020), and the China Medical University Hospital (DMR-101-010). J.H. Chen, MD, PhD, Associate Professor, China Medical University, China Medical University Hospital; J.L. Lan, MD, Professor, China Medical University, China Medical University Hospital; C.F. Cheng, MSc; W.M. Liang, PhD, Professor, China Medical University; H.Y. Lin, MD, Associate Professor, National Yang-Ming University, Veterans General Hospital; G.J. Tsay, MD, PhD, Professor, Chung-Shan Medical University; W.T. Yeh, MSc, Academia Sinica; W.H. Pan, PhD, Professor, Academia Sinica, National Health Research Institutes. Address correspondence to Dr. J.H. Chen, School of Medicine, China Medical University, No. 91 Hsueh-Shih Road, Taichung, Taiwan 40402. E-mail: d91842001@ntu.edu.tw. Accepted for publication April 20, 2015.
Wen-Harn Pan
From the School of Medicine, China Medical University, Section of Immunology and Rheumatology, Department of Internal Medicine, China Medical University Hospital; Department of Public Health, and Graduate Institute of Biostatistics, Biostatistics Center, China Medical University; Institute of Microbiology and Immunology, Chung-Shan Medical University, Taichung; School of Medicine, National Yang-Ming University, Section of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Veterans General Hospital; Institute of Biomedical Sciences, Academia Sinica, Taipei; Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan. Supported by grants from the Department of Health, Executive Yuan, Taiwan (NSC97-2314-B-039-010-MY3, NSC100-2314-B-039-012, NSC101-2314-B-039-020, MOST103-2314-B-039-020), and the China Medical University Hospital (DMR-101-010). J.H. Chen, MD, PhD, Associate Professor, China Medical University, China Medical University Hospital; J.L. Lan, MD, Professor, China Medical University, China Medical University Hospital; C.F. Cheng, MSc; W.M. Liang, PhD, Professor, China Medical University; H.Y. Lin, MD, Associate Professor, National Yang-Ming University, Veterans General Hospital; G.J. Tsay, MD, PhD, Professor, Chung-Shan Medical University; W.T. Yeh, MSc, Academia Sinica; W.H. Pan, PhD, Professor, Academia Sinica, National Health Research Institutes. Address correspondence to Dr. J.H. Chen, School of Medicine, China Medical University, No. 91 Hsueh-Shih Road, Taichung, Taiwan 40402. E-mail: d91842001@ntu.edu.tw. Accepted for publication April 20, 2015.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Effect of Urate-lowering Therapy on the Risk of Cardiovascular Disease and All-cause Mortality in Patients with Gout: A Case-matched Cohort Study
Jiunn-Horng Chen, Joung-Liang Lan, Chi-Fung Cheng, Wen-Miin Liang, Hsiao-Yi Lin, Gregory J. Tsay, Wen-Ting Yeh, Wen-Harn Pan
The Journal of Rheumatology Jun 2015, jrheum.141542; DOI: 10.3899/jrheum.141542
Effect of Urate-lowering Therapy on the Risk of Cardiovascular Disease and All-cause Mortality in Patients with Gout: A Case-matched Cohort Study
Jiunn-Horng Chen, Joung-Liang Lan, Chi-Fung Cheng, Wen-Miin Liang, Hsiao-Yi Lin, Gregory J. Tsay, Wen-Ting Yeh, Wen-Harn Pan
The Journal of Rheumatology Jun 2015, jrheum.141542; DOI: 10.3899/jrheum.141542