Research ArticleArticle
Consensus on the Need for a Hierarchical List of Patient-reported Pain Outcomes for Metaanalyses of Knee Osteoarthritis Trials: An OMERACT Objective
Robin Christensen, Lara J. Maxwell, Peter Jüni, David Tovey, Paula R. Williamson, Maarten Boers, Niti Goel, Rachelle Buchbinder, Lyn March, Caroline B. Terwee, Jasvinder A. Singh and Peter Tugwell
The Journal of Rheumatology May 2015, jrheum.141384; DOI: https://doi.org/10.3899/jrheum.141384
Robin Christensen
From the Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; Bispebjerg and Frederiksberg, Denmark; Institute of Population Health, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern, Bern, Switzerland; Cochrane Collaboration, London; Department of Biostatistics, University of Liverpool, Liverpool, UK; departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center, Amsterdam, The Netherlands; Quintiles Inc.; Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health, Melbourne; Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology, Sydney, Australia; Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Birmingham Veterans Affairs (VA) Medical Center and University of Alabama at Birmingham, Birmingham, Alabama, USA. RC is supported by unrestricted grants from The Oak Foundation; RB is supported in part by an Australian National Health and Research Council Practitioner Fellowship; PRW is supported by grants for the COMET Initiative from the Medical Research Council and the European Commission; JAS is supported by grants from the US Agency for Health Quality and Research Center for Education and Research on Therapeutics U19 HS021110, US National Institute of Arthritis and Musculoskeletal and Skin Diseases P50 AR060772 and U34 AR062891, US National Institute on Aging U01 AG018947, US National Cancer Institute U10 CA149950, the resources and the use of facilities at the VA Medical Center at Birmingham, Alabama, USA, and research contract CE-1304-6631 from the Patient-Centered Outcomes Research Institute. R. Christensen, BSc, MSc, PhD, Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; L.J. Maxwell, Institute of Population Health, University of Ottawa; P. Jüni, MD, Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern; D. Tovey, Cochrane Collaboration; P.R. Williamson, Department of Biostatistics, University of Liverpool; M. Boers, MD, PhD, Departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center; N. Goel, Quintiles Inc., Division of Rheumatology, Department of Medicine, Duke University School of Medicine, and Patient Research Partner; R.S. Buchbinder, MBBS (Hons), MSc, PhD, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health; L. March, MD, PhD, Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology; C.B. Terwee, Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center; J.A. Singh, MBBS, MPH, Birmingham VA Medical Center and University of Alabama at Birmingham; P. Tugwell, MD, MSc, The Department of Medicine, University of Ottawa. Address correspondence to Prof. R. Christensen, Copenhagen University Hospital at Frederiksberg, Musculoskeletal Statistics Unit, The Parker Institute, Nordre Fasanvej 57, Copenhagen F, DK-2000, Denmark. E-mail: robin.christensen@regionh.dk
Lara J. Maxwell
From the Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; Bispebjerg and Frederiksberg, Denmark; Institute of Population Health, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern, Bern, Switzerland; Cochrane Collaboration, London; Department of Biostatistics, University of Liverpool, Liverpool, UK; departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center, Amsterdam, The Netherlands; Quintiles Inc.; Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health, Melbourne; Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology, Sydney, Australia; Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Birmingham Veterans Affairs (VA) Medical Center and University of Alabama at Birmingham, Birmingham, Alabama, USA. RC is supported by unrestricted grants from The Oak Foundation; RB is supported in part by an Australian National Health and Research Council Practitioner Fellowship; PRW is supported by grants for the COMET Initiative from the Medical Research Council and the European Commission; JAS is supported by grants from the US Agency for Health Quality and Research Center for Education and Research on Therapeutics U19 HS021110, US National Institute of Arthritis and Musculoskeletal and Skin Diseases P50 AR060772 and U34 AR062891, US National Institute on Aging U01 AG018947, US National Cancer Institute U10 CA149950, the resources and the use of facilities at the VA Medical Center at Birmingham, Alabama, USA, and research contract CE-1304-6631 from the Patient-Centered Outcomes Research Institute. R. Christensen, BSc, MSc, PhD, Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; L.J. Maxwell, Institute of Population Health, University of Ottawa; P. Jüni, MD, Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern; D. Tovey, Cochrane Collaboration; P.R. Williamson, Department of Biostatistics, University of Liverpool; M. Boers, MD, PhD, Departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center; N. Goel, Quintiles Inc., Division of Rheumatology, Department of Medicine, Duke University School of Medicine, and Patient Research Partner; R.S. Buchbinder, MBBS (Hons), MSc, PhD, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health; L. March, MD, PhD, Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology; C.B. Terwee, Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center; J.A. Singh, MBBS, MPH, Birmingham VA Medical Center and University of Alabama at Birmingham; P. Tugwell, MD, MSc, The Department of Medicine, University of Ottawa. Address correspondence to Prof. R. Christensen, Copenhagen University Hospital at Frederiksberg, Musculoskeletal Statistics Unit, The Parker Institute, Nordre Fasanvej 57, Copenhagen F, DK-2000, Denmark. E-mail: robin.christensen@regionh.dk
Peter Jüni
From the Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; Bispebjerg and Frederiksberg, Denmark; Institute of Population Health, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern, Bern, Switzerland; Cochrane Collaboration, London; Department of Biostatistics, University of Liverpool, Liverpool, UK; departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center, Amsterdam, The Netherlands; Quintiles Inc.; Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health, Melbourne; Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology, Sydney, Australia; Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Birmingham Veterans Affairs (VA) Medical Center and University of Alabama at Birmingham, Birmingham, Alabama, USA. RC is supported by unrestricted grants from The Oak Foundation; RB is supported in part by an Australian National Health and Research Council Practitioner Fellowship; PRW is supported by grants for the COMET Initiative from the Medical Research Council and the European Commission; JAS is supported by grants from the US Agency for Health Quality and Research Center for Education and Research on Therapeutics U19 HS021110, US National Institute of Arthritis and Musculoskeletal and Skin Diseases P50 AR060772 and U34 AR062891, US National Institute on Aging U01 AG018947, US National Cancer Institute U10 CA149950, the resources and the use of facilities at the VA Medical Center at Birmingham, Alabama, USA, and research contract CE-1304-6631 from the Patient-Centered Outcomes Research Institute. R. Christensen, BSc, MSc, PhD, Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; L.J. Maxwell, Institute of Population Health, University of Ottawa; P. Jüni, MD, Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern; D. Tovey, Cochrane Collaboration; P.R. Williamson, Department of Biostatistics, University of Liverpool; M. Boers, MD, PhD, Departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center; N. Goel, Quintiles Inc., Division of Rheumatology, Department of Medicine, Duke University School of Medicine, and Patient Research Partner; R.S. Buchbinder, MBBS (Hons), MSc, PhD, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health; L. March, MD, PhD, Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology; C.B. Terwee, Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center; J.A. Singh, MBBS, MPH, Birmingham VA Medical Center and University of Alabama at Birmingham; P. Tugwell, MD, MSc, The Department of Medicine, University of Ottawa. Address correspondence to Prof. R. Christensen, Copenhagen University Hospital at Frederiksberg, Musculoskeletal Statistics Unit, The Parker Institute, Nordre Fasanvej 57, Copenhagen F, DK-2000, Denmark. E-mail: robin.christensen@regionh.dk
David Tovey
From the Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; Bispebjerg and Frederiksberg, Denmark; Institute of Population Health, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern, Bern, Switzerland; Cochrane Collaboration, London; Department of Biostatistics, University of Liverpool, Liverpool, UK; departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center, Amsterdam, The Netherlands; Quintiles Inc.; Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health, Melbourne; Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology, Sydney, Australia; Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Birmingham Veterans Affairs (VA) Medical Center and University of Alabama at Birmingham, Birmingham, Alabama, USA. RC is supported by unrestricted grants from The Oak Foundation; RB is supported in part by an Australian National Health and Research Council Practitioner Fellowship; PRW is supported by grants for the COMET Initiative from the Medical Research Council and the European Commission; JAS is supported by grants from the US Agency for Health Quality and Research Center for Education and Research on Therapeutics U19 HS021110, US National Institute of Arthritis and Musculoskeletal and Skin Diseases P50 AR060772 and U34 AR062891, US National Institute on Aging U01 AG018947, US National Cancer Institute U10 CA149950, the resources and the use of facilities at the VA Medical Center at Birmingham, Alabama, USA, and research contract CE-1304-6631 from the Patient-Centered Outcomes Research Institute. R. Christensen, BSc, MSc, PhD, Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; L.J. Maxwell, Institute of Population Health, University of Ottawa; P. Jüni, MD, Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern; D. Tovey, Cochrane Collaboration; P.R. Williamson, Department of Biostatistics, University of Liverpool; M. Boers, MD, PhD, Departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center; N. Goel, Quintiles Inc., Division of Rheumatology, Department of Medicine, Duke University School of Medicine, and Patient Research Partner; R.S. Buchbinder, MBBS (Hons), MSc, PhD, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health; L. March, MD, PhD, Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology; C.B. Terwee, Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center; J.A. Singh, MBBS, MPH, Birmingham VA Medical Center and University of Alabama at Birmingham; P. Tugwell, MD, MSc, The Department of Medicine, University of Ottawa. Address correspondence to Prof. R. Christensen, Copenhagen University Hospital at Frederiksberg, Musculoskeletal Statistics Unit, The Parker Institute, Nordre Fasanvej 57, Copenhagen F, DK-2000, Denmark. E-mail: robin.christensen@regionh.dk
Paula R. Williamson
From the Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; Bispebjerg and Frederiksberg, Denmark; Institute of Population Health, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern, Bern, Switzerland; Cochrane Collaboration, London; Department of Biostatistics, University of Liverpool, Liverpool, UK; departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center, Amsterdam, The Netherlands; Quintiles Inc.; Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health, Melbourne; Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology, Sydney, Australia; Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Birmingham Veterans Affairs (VA) Medical Center and University of Alabama at Birmingham, Birmingham, Alabama, USA. RC is supported by unrestricted grants from The Oak Foundation; RB is supported in part by an Australian National Health and Research Council Practitioner Fellowship; PRW is supported by grants for the COMET Initiative from the Medical Research Council and the European Commission; JAS is supported by grants from the US Agency for Health Quality and Research Center for Education and Research on Therapeutics U19 HS021110, US National Institute of Arthritis and Musculoskeletal and Skin Diseases P50 AR060772 and U34 AR062891, US National Institute on Aging U01 AG018947, US National Cancer Institute U10 CA149950, the resources and the use of facilities at the VA Medical Center at Birmingham, Alabama, USA, and research contract CE-1304-6631 from the Patient-Centered Outcomes Research Institute. R. Christensen, BSc, MSc, PhD, Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; L.J. Maxwell, Institute of Population Health, University of Ottawa; P. Jüni, MD, Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern; D. Tovey, Cochrane Collaboration; P.R. Williamson, Department of Biostatistics, University of Liverpool; M. Boers, MD, PhD, Departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center; N. Goel, Quintiles Inc., Division of Rheumatology, Department of Medicine, Duke University School of Medicine, and Patient Research Partner; R.S. Buchbinder, MBBS (Hons), MSc, PhD, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health; L. March, MD, PhD, Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology; C.B. Terwee, Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center; J.A. Singh, MBBS, MPH, Birmingham VA Medical Center and University of Alabama at Birmingham; P. Tugwell, MD, MSc, The Department of Medicine, University of Ottawa. Address correspondence to Prof. R. Christensen, Copenhagen University Hospital at Frederiksberg, Musculoskeletal Statistics Unit, The Parker Institute, Nordre Fasanvej 57, Copenhagen F, DK-2000, Denmark. E-mail: robin.christensen@regionh.dk
Maarten Boers
From the Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; Bispebjerg and Frederiksberg, Denmark; Institute of Population Health, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern, Bern, Switzerland; Cochrane Collaboration, London; Department of Biostatistics, University of Liverpool, Liverpool, UK; departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center, Amsterdam, The Netherlands; Quintiles Inc.; Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health, Melbourne; Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology, Sydney, Australia; Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Birmingham Veterans Affairs (VA) Medical Center and University of Alabama at Birmingham, Birmingham, Alabama, USA. RC is supported by unrestricted grants from The Oak Foundation; RB is supported in part by an Australian National Health and Research Council Practitioner Fellowship; PRW is supported by grants for the COMET Initiative from the Medical Research Council and the European Commission; JAS is supported by grants from the US Agency for Health Quality and Research Center for Education and Research on Therapeutics U19 HS021110, US National Institute of Arthritis and Musculoskeletal and Skin Diseases P50 AR060772 and U34 AR062891, US National Institute on Aging U01 AG018947, US National Cancer Institute U10 CA149950, the resources and the use of facilities at the VA Medical Center at Birmingham, Alabama, USA, and research contract CE-1304-6631 from the Patient-Centered Outcomes Research Institute. R. Christensen, BSc, MSc, PhD, Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; L.J. Maxwell, Institute of Population Health, University of Ottawa; P. Jüni, MD, Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern; D. Tovey, Cochrane Collaboration; P.R. Williamson, Department of Biostatistics, University of Liverpool; M. Boers, MD, PhD, Departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center; N. Goel, Quintiles Inc., Division of Rheumatology, Department of Medicine, Duke University School of Medicine, and Patient Research Partner; R.S. Buchbinder, MBBS (Hons), MSc, PhD, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health; L. March, MD, PhD, Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology; C.B. Terwee, Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center; J.A. Singh, MBBS, MPH, Birmingham VA Medical Center and University of Alabama at Birmingham; P. Tugwell, MD, MSc, The Department of Medicine, University of Ottawa. Address correspondence to Prof. R. Christensen, Copenhagen University Hospital at Frederiksberg, Musculoskeletal Statistics Unit, The Parker Institute, Nordre Fasanvej 57, Copenhagen F, DK-2000, Denmark. E-mail: robin.christensen@regionh.dk
Niti Goel
From the Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; Bispebjerg and Frederiksberg, Denmark; Institute of Population Health, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern, Bern, Switzerland; Cochrane Collaboration, London; Department of Biostatistics, University of Liverpool, Liverpool, UK; departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center, Amsterdam, The Netherlands; Quintiles Inc.; Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health, Melbourne; Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology, Sydney, Australia; Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Birmingham Veterans Affairs (VA) Medical Center and University of Alabama at Birmingham, Birmingham, Alabama, USA. RC is supported by unrestricted grants from The Oak Foundation; RB is supported in part by an Australian National Health and Research Council Practitioner Fellowship; PRW is supported by grants for the COMET Initiative from the Medical Research Council and the European Commission; JAS is supported by grants from the US Agency for Health Quality and Research Center for Education and Research on Therapeutics U19 HS021110, US National Institute of Arthritis and Musculoskeletal and Skin Diseases P50 AR060772 and U34 AR062891, US National Institute on Aging U01 AG018947, US National Cancer Institute U10 CA149950, the resources and the use of facilities at the VA Medical Center at Birmingham, Alabama, USA, and research contract CE-1304-6631 from the Patient-Centered Outcomes Research Institute. R. Christensen, BSc, MSc, PhD, Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; L.J. Maxwell, Institute of Population Health, University of Ottawa; P. Jüni, MD, Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern; D. Tovey, Cochrane Collaboration; P.R. Williamson, Department of Biostatistics, University of Liverpool; M. Boers, MD, PhD, Departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center; N. Goel, Quintiles Inc., Division of Rheumatology, Department of Medicine, Duke University School of Medicine, and Patient Research Partner; R.S. Buchbinder, MBBS (Hons), MSc, PhD, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health; L. March, MD, PhD, Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology; C.B. Terwee, Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center; J.A. Singh, MBBS, MPH, Birmingham VA Medical Center and University of Alabama at Birmingham; P. Tugwell, MD, MSc, The Department of Medicine, University of Ottawa. Address correspondence to Prof. R. Christensen, Copenhagen University Hospital at Frederiksberg, Musculoskeletal Statistics Unit, The Parker Institute, Nordre Fasanvej 57, Copenhagen F, DK-2000, Denmark. E-mail: robin.christensen@regionh.dk
Rachelle Buchbinder
From the Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; Bispebjerg and Frederiksberg, Denmark; Institute of Population Health, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern, Bern, Switzerland; Cochrane Collaboration, London; Department of Biostatistics, University of Liverpool, Liverpool, UK; departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center, Amsterdam, The Netherlands; Quintiles Inc.; Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health, Melbourne; Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology, Sydney, Australia; Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Birmingham Veterans Affairs (VA) Medical Center and University of Alabama at Birmingham, Birmingham, Alabama, USA. RC is supported by unrestricted grants from The Oak Foundation; RB is supported in part by an Australian National Health and Research Council Practitioner Fellowship; PRW is supported by grants for the COMET Initiative from the Medical Research Council and the European Commission; JAS is supported by grants from the US Agency for Health Quality and Research Center for Education and Research on Therapeutics U19 HS021110, US National Institute of Arthritis and Musculoskeletal and Skin Diseases P50 AR060772 and U34 AR062891, US National Institute on Aging U01 AG018947, US National Cancer Institute U10 CA149950, the resources and the use of facilities at the VA Medical Center at Birmingham, Alabama, USA, and research contract CE-1304-6631 from the Patient-Centered Outcomes Research Institute. R. Christensen, BSc, MSc, PhD, Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; L.J. Maxwell, Institute of Population Health, University of Ottawa; P. Jüni, MD, Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern; D. Tovey, Cochrane Collaboration; P.R. Williamson, Department of Biostatistics, University of Liverpool; M. Boers, MD, PhD, Departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center; N. Goel, Quintiles Inc., Division of Rheumatology, Department of Medicine, Duke University School of Medicine, and Patient Research Partner; R.S. Buchbinder, MBBS (Hons), MSc, PhD, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health; L. March, MD, PhD, Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology; C.B. Terwee, Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center; J.A. Singh, MBBS, MPH, Birmingham VA Medical Center and University of Alabama at Birmingham; P. Tugwell, MD, MSc, The Department of Medicine, University of Ottawa. Address correspondence to Prof. R. Christensen, Copenhagen University Hospital at Frederiksberg, Musculoskeletal Statistics Unit, The Parker Institute, Nordre Fasanvej 57, Copenhagen F, DK-2000, Denmark. E-mail: robin.christensen@regionh.dk
Lyn March
From the Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; Bispebjerg and Frederiksberg, Denmark; Institute of Population Health, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern, Bern, Switzerland; Cochrane Collaboration, London; Department of Biostatistics, University of Liverpool, Liverpool, UK; departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center, Amsterdam, The Netherlands; Quintiles Inc.; Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health, Melbourne; Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology, Sydney, Australia; Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Birmingham Veterans Affairs (VA) Medical Center and University of Alabama at Birmingham, Birmingham, Alabama, USA. RC is supported by unrestricted grants from The Oak Foundation; RB is supported in part by an Australian National Health and Research Council Practitioner Fellowship; PRW is supported by grants for the COMET Initiative from the Medical Research Council and the European Commission; JAS is supported by grants from the US Agency for Health Quality and Research Center for Education and Research on Therapeutics U19 HS021110, US National Institute of Arthritis and Musculoskeletal and Skin Diseases P50 AR060772 and U34 AR062891, US National Institute on Aging U01 AG018947, US National Cancer Institute U10 CA149950, the resources and the use of facilities at the VA Medical Center at Birmingham, Alabama, USA, and research contract CE-1304-6631 from the Patient-Centered Outcomes Research Institute. R. Christensen, BSc, MSc, PhD, Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; L.J. Maxwell, Institute of Population Health, University of Ottawa; P. Jüni, MD, Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern; D. Tovey, Cochrane Collaboration; P.R. Williamson, Department of Biostatistics, University of Liverpool; M. Boers, MD, PhD, Departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center; N. Goel, Quintiles Inc., Division of Rheumatology, Department of Medicine, Duke University School of Medicine, and Patient Research Partner; R.S. Buchbinder, MBBS (Hons), MSc, PhD, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health; L. March, MD, PhD, Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology; C.B. Terwee, Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center; J.A. Singh, MBBS, MPH, Birmingham VA Medical Center and University of Alabama at Birmingham; P. Tugwell, MD, MSc, The Department of Medicine, University of Ottawa. Address correspondence to Prof. R. Christensen, Copenhagen University Hospital at Frederiksberg, Musculoskeletal Statistics Unit, The Parker Institute, Nordre Fasanvej 57, Copenhagen F, DK-2000, Denmark. E-mail: robin.christensen@regionh.dk
Caroline B. Terwee
From the Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; Bispebjerg and Frederiksberg, Denmark; Institute of Population Health, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern, Bern, Switzerland; Cochrane Collaboration, London; Department of Biostatistics, University of Liverpool, Liverpool, UK; departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center, Amsterdam, The Netherlands; Quintiles Inc.; Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health, Melbourne; Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology, Sydney, Australia; Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Birmingham Veterans Affairs (VA) Medical Center and University of Alabama at Birmingham, Birmingham, Alabama, USA. RC is supported by unrestricted grants from The Oak Foundation; RB is supported in part by an Australian National Health and Research Council Practitioner Fellowship; PRW is supported by grants for the COMET Initiative from the Medical Research Council and the European Commission; JAS is supported by grants from the US Agency for Health Quality and Research Center for Education and Research on Therapeutics U19 HS021110, US National Institute of Arthritis and Musculoskeletal and Skin Diseases P50 AR060772 and U34 AR062891, US National Institute on Aging U01 AG018947, US National Cancer Institute U10 CA149950, the resources and the use of facilities at the VA Medical Center at Birmingham, Alabama, USA, and research contract CE-1304-6631 from the Patient-Centered Outcomes Research Institute. R. Christensen, BSc, MSc, PhD, Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; L.J. Maxwell, Institute of Population Health, University of Ottawa; P. Jüni, MD, Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern; D. Tovey, Cochrane Collaboration; P.R. Williamson, Department of Biostatistics, University of Liverpool; M. Boers, MD, PhD, Departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center; N. Goel, Quintiles Inc., Division of Rheumatology, Department of Medicine, Duke University School of Medicine, and Patient Research Partner; R.S. Buchbinder, MBBS (Hons), MSc, PhD, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health; L. March, MD, PhD, Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology; C.B. Terwee, Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center; J.A. Singh, MBBS, MPH, Birmingham VA Medical Center and University of Alabama at Birmingham; P. Tugwell, MD, MSc, The Department of Medicine, University of Ottawa. Address correspondence to Prof. R. Christensen, Copenhagen University Hospital at Frederiksberg, Musculoskeletal Statistics Unit, The Parker Institute, Nordre Fasanvej 57, Copenhagen F, DK-2000, Denmark. E-mail: robin.christensen@regionh.dk
Jasvinder A. Singh
From the Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; Bispebjerg and Frederiksberg, Denmark; Institute of Population Health, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern, Bern, Switzerland; Cochrane Collaboration, London; Department of Biostatistics, University of Liverpool, Liverpool, UK; departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center, Amsterdam, The Netherlands; Quintiles Inc.; Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health, Melbourne; Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology, Sydney, Australia; Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Birmingham Veterans Affairs (VA) Medical Center and University of Alabama at Birmingham, Birmingham, Alabama, USA. RC is supported by unrestricted grants from The Oak Foundation; RB is supported in part by an Australian National Health and Research Council Practitioner Fellowship; PRW is supported by grants for the COMET Initiative from the Medical Research Council and the European Commission; JAS is supported by grants from the US Agency for Health Quality and Research Center for Education and Research on Therapeutics U19 HS021110, US National Institute of Arthritis and Musculoskeletal and Skin Diseases P50 AR060772 and U34 AR062891, US National Institute on Aging U01 AG018947, US National Cancer Institute U10 CA149950, the resources and the use of facilities at the VA Medical Center at Birmingham, Alabama, USA, and research contract CE-1304-6631 from the Patient-Centered Outcomes Research Institute. R. Christensen, BSc, MSc, PhD, Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; L.J. Maxwell, Institute of Population Health, University of Ottawa; P. Jüni, MD, Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern; D. Tovey, Cochrane Collaboration; P.R. Williamson, Department of Biostatistics, University of Liverpool; M. Boers, MD, PhD, Departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center; N. Goel, Quintiles Inc., Division of Rheumatology, Department of Medicine, Duke University School of Medicine, and Patient Research Partner; R.S. Buchbinder, MBBS (Hons), MSc, PhD, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health; L. March, MD, PhD, Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology; C.B. Terwee, Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center; J.A. Singh, MBBS, MPH, Birmingham VA Medical Center and University of Alabama at Birmingham; P. Tugwell, MD, MSc, The Department of Medicine, University of Ottawa. Address correspondence to Prof. R. Christensen, Copenhagen University Hospital at Frederiksberg, Musculoskeletal Statistics Unit, The Parker Institute, Nordre Fasanvej 57, Copenhagen F, DK-2000, Denmark. E-mail: robin.christensen@regionh.dk
Peter Tugwell
From the Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; Bispebjerg and Frederiksberg, Denmark; Institute of Population Health, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern, Bern, Switzerland; Cochrane Collaboration, London; Department of Biostatistics, University of Liverpool, Liverpool, UK; departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center, Amsterdam, The Netherlands; Quintiles Inc.; Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health, Melbourne; Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology, Sydney, Australia; Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Birmingham Veterans Affairs (VA) Medical Center and University of Alabama at Birmingham, Birmingham, Alabama, USA. RC is supported by unrestricted grants from The Oak Foundation; RB is supported in part by an Australian National Health and Research Council Practitioner Fellowship; PRW is supported by grants for the COMET Initiative from the Medical Research Council and the European Commission; JAS is supported by grants from the US Agency for Health Quality and Research Center for Education and Research on Therapeutics U19 HS021110, US National Institute of Arthritis and Musculoskeletal and Skin Diseases P50 AR060772 and U34 AR062891, US National Institute on Aging U01 AG018947, US National Cancer Institute U10 CA149950, the resources and the use of facilities at the VA Medical Center at Birmingham, Alabama, USA, and research contract CE-1304-6631 from the Patient-Centered Outcomes Research Institute. R. Christensen, BSc, MSc, PhD, Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital; L.J. Maxwell, Institute of Population Health, University of Ottawa; P. Jüni, MD, Institute of Social and Preventive Medicine and Clinical Trials Unit Bern, Department of Clinical Research, University of Bern; D. Tovey, Cochrane Collaboration; P.R. Williamson, Department of Biostatistics, University of Liverpool; M. Boers, MD, PhD, Departments of Epidemiology and Biostatistics, and Rheumatology, VU University Medical Center; N. Goel, Quintiles Inc., Division of Rheumatology, Department of Medicine, Duke University School of Medicine, and Patient Research Partner; R.S. Buchbinder, MBBS (Hons), MSc, PhD, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Monash Department of Clinical Epidemiology, Cabrini Health; L. March, MD, PhD, Northern Clinical School, Institute of Bone and Joint Research, University of Sydney, Department of Rheumatology; C.B. Terwee, Department of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Center; J.A. Singh, MBBS, MPH, Birmingham VA Medical Center and University of Alabama at Birmingham; P. Tugwell, MD, MSc, The Department of Medicine, University of Ottawa. Address correspondence to Prof. R. Christensen, Copenhagen University Hospital at Frederiksberg, Musculoskeletal Statistics Unit, The Parker Institute, Nordre Fasanvej 57, Copenhagen F, DK-2000, Denmark. E-mail: robin.christensen@regionh.dk
In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Consensus on the Need for a Hierarchical List of Patient-reported Pain Outcomes for Metaanalyses of Knee Osteoarthritis Trials: An OMERACT Objective
Robin Christensen, Lara J. Maxwell, Peter Jüni, David Tovey, Paula R. Williamson, Maarten Boers, Niti Goel, Rachelle Buchbinder, Lyn March, Caroline B. Terwee, Jasvinder A. Singh, Peter Tugwell
The Journal of Rheumatology May 2015, jrheum.141384; DOI: 10.3899/jrheum.141384
Consensus on the Need for a Hierarchical List of Patient-reported Pain Outcomes for Metaanalyses of Knee Osteoarthritis Trials: An OMERACT Objective
Robin Christensen, Lara J. Maxwell, Peter Jüni, David Tovey, Paula R. Williamson, Maarten Boers, Niti Goel, Rachelle Buchbinder, Lyn March, Caroline B. Terwee, Jasvinder A. Singh, Peter Tugwell
The Journal of Rheumatology May 2015, jrheum.141384; DOI: 10.3899/jrheum.141384