Research ArticleArticle
Inconsistent Treatment with Disease-modifying Antirheumatic Drugs: A Longitudinal Data Analysis
Maria D. Mjaavatten, Helga Radner, Kazuki Yoshida, Nancy A. Shadick, Michelle L. Frits, Christine K. Iannaccone, Tore K. Kvien, Michael E. Weinblatt and Daniel H. Solomon
The Journal of Rheumatology October 2014, jrheum.140306; DOI: https://doi.org/10.3899/jrheum.140306
Maria D. Mjaavatten
From the Division of Rheumatology, Immunology and Allergy, and the Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Boston, Massachusetts, USA; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria; Department of Rheumatology, Kameda Medical Center, Kamogawa, Chiba Prefecture, Japan. Dr. Solomon is supported by a mentoring award from the US National Institutes of Health (K24 AR055989). The Brigham and Women’s Hospital Rheumatoid Arthritis Sequential Study receives support from Bristol Myers Squibb, Medimmune, and Crescendo Bioscience. M.D. Mjaavatten, MD, PhD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; H. Radner, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna; K. Yoshida, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Kameda Medical Center; N.A. Shadick, MD, MPH; M.L. Frits, BA; C.K. Iannaccone, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; T.K. Kvien, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; M.E. Weinblatt, MD, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; D.H. Solomon, MD, MPH, Division of Rheumatology, and Immunology and Allergy, and Division of Pharmacoepidemiology, Brigham and Women’s Hospital. Address correspondence to Dr. M.D. Mjaavatten, Department of Rheumatology, Diakonhjemmet Hospital, P.O. Box 23, Vinderen, 0319 Oslo, Norway. E-mail: maria_mjaavatten@hotmail.com. Accepted for publication August 26, 2014.
Helga Radner
From the Division of Rheumatology, Immunology and Allergy, and the Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Boston, Massachusetts, USA; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria; Department of Rheumatology, Kameda Medical Center, Kamogawa, Chiba Prefecture, Japan. Dr. Solomon is supported by a mentoring award from the US National Institutes of Health (K24 AR055989). The Brigham and Women’s Hospital Rheumatoid Arthritis Sequential Study receives support from Bristol Myers Squibb, Medimmune, and Crescendo Bioscience. M.D. Mjaavatten, MD, PhD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; H. Radner, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna; K. Yoshida, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Kameda Medical Center; N.A. Shadick, MD, MPH; M.L. Frits, BA; C.K. Iannaccone, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; T.K. Kvien, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; M.E. Weinblatt, MD, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; D.H. Solomon, MD, MPH, Division of Rheumatology, and Immunology and Allergy, and Division of Pharmacoepidemiology, Brigham and Women’s Hospital. Address correspondence to Dr. M.D. Mjaavatten, Department of Rheumatology, Diakonhjemmet Hospital, P.O. Box 23, Vinderen, 0319 Oslo, Norway. E-mail: maria_mjaavatten@hotmail.com. Accepted for publication August 26, 2014.
Kazuki Yoshida
From the Division of Rheumatology, Immunology and Allergy, and the Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Boston, Massachusetts, USA; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria; Department of Rheumatology, Kameda Medical Center, Kamogawa, Chiba Prefecture, Japan. Dr. Solomon is supported by a mentoring award from the US National Institutes of Health (K24 AR055989). The Brigham and Women’s Hospital Rheumatoid Arthritis Sequential Study receives support from Bristol Myers Squibb, Medimmune, and Crescendo Bioscience. M.D. Mjaavatten, MD, PhD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; H. Radner, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna; K. Yoshida, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Kameda Medical Center; N.A. Shadick, MD, MPH; M.L. Frits, BA; C.K. Iannaccone, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; T.K. Kvien, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; M.E. Weinblatt, MD, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; D.H. Solomon, MD, MPH, Division of Rheumatology, and Immunology and Allergy, and Division of Pharmacoepidemiology, Brigham and Women’s Hospital. Address correspondence to Dr. M.D. Mjaavatten, Department of Rheumatology, Diakonhjemmet Hospital, P.O. Box 23, Vinderen, 0319 Oslo, Norway. E-mail: maria_mjaavatten@hotmail.com. Accepted for publication August 26, 2014.
Nancy A. Shadick
From the Division of Rheumatology, Immunology and Allergy, and the Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Boston, Massachusetts, USA; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria; Department of Rheumatology, Kameda Medical Center, Kamogawa, Chiba Prefecture, Japan. Dr. Solomon is supported by a mentoring award from the US National Institutes of Health (K24 AR055989). The Brigham and Women’s Hospital Rheumatoid Arthritis Sequential Study receives support from Bristol Myers Squibb, Medimmune, and Crescendo Bioscience. M.D. Mjaavatten, MD, PhD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; H. Radner, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna; K. Yoshida, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Kameda Medical Center; N.A. Shadick, MD, MPH; M.L. Frits, BA; C.K. Iannaccone, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; T.K. Kvien, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; M.E. Weinblatt, MD, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; D.H. Solomon, MD, MPH, Division of Rheumatology, and Immunology and Allergy, and Division of Pharmacoepidemiology, Brigham and Women’s Hospital. Address correspondence to Dr. M.D. Mjaavatten, Department of Rheumatology, Diakonhjemmet Hospital, P.O. Box 23, Vinderen, 0319 Oslo, Norway. E-mail: maria_mjaavatten@hotmail.com. Accepted for publication August 26, 2014.
Michelle L. Frits
From the Division of Rheumatology, Immunology and Allergy, and the Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Boston, Massachusetts, USA; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria; Department of Rheumatology, Kameda Medical Center, Kamogawa, Chiba Prefecture, Japan. Dr. Solomon is supported by a mentoring award from the US National Institutes of Health (K24 AR055989). The Brigham and Women’s Hospital Rheumatoid Arthritis Sequential Study receives support from Bristol Myers Squibb, Medimmune, and Crescendo Bioscience. M.D. Mjaavatten, MD, PhD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; H. Radner, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna; K. Yoshida, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Kameda Medical Center; N.A. Shadick, MD, MPH; M.L. Frits, BA; C.K. Iannaccone, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; T.K. Kvien, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; M.E. Weinblatt, MD, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; D.H. Solomon, MD, MPH, Division of Rheumatology, and Immunology and Allergy, and Division of Pharmacoepidemiology, Brigham and Women’s Hospital. Address correspondence to Dr. M.D. Mjaavatten, Department of Rheumatology, Diakonhjemmet Hospital, P.O. Box 23, Vinderen, 0319 Oslo, Norway. E-mail: maria_mjaavatten@hotmail.com. Accepted for publication August 26, 2014.
Christine K. Iannaccone
From the Division of Rheumatology, Immunology and Allergy, and the Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Boston, Massachusetts, USA; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria; Department of Rheumatology, Kameda Medical Center, Kamogawa, Chiba Prefecture, Japan. Dr. Solomon is supported by a mentoring award from the US National Institutes of Health (K24 AR055989). The Brigham and Women’s Hospital Rheumatoid Arthritis Sequential Study receives support from Bristol Myers Squibb, Medimmune, and Crescendo Bioscience. M.D. Mjaavatten, MD, PhD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; H. Radner, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna; K. Yoshida, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Kameda Medical Center; N.A. Shadick, MD, MPH; M.L. Frits, BA; C.K. Iannaccone, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; T.K. Kvien, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; M.E. Weinblatt, MD, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; D.H. Solomon, MD, MPH, Division of Rheumatology, and Immunology and Allergy, and Division of Pharmacoepidemiology, Brigham and Women’s Hospital. Address correspondence to Dr. M.D. Mjaavatten, Department of Rheumatology, Diakonhjemmet Hospital, P.O. Box 23, Vinderen, 0319 Oslo, Norway. E-mail: maria_mjaavatten@hotmail.com. Accepted for publication August 26, 2014.
Tore K. Kvien
From the Division of Rheumatology, Immunology and Allergy, and the Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Boston, Massachusetts, USA; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria; Department of Rheumatology, Kameda Medical Center, Kamogawa, Chiba Prefecture, Japan. Dr. Solomon is supported by a mentoring award from the US National Institutes of Health (K24 AR055989). The Brigham and Women’s Hospital Rheumatoid Arthritis Sequential Study receives support from Bristol Myers Squibb, Medimmune, and Crescendo Bioscience. M.D. Mjaavatten, MD, PhD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; H. Radner, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna; K. Yoshida, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Kameda Medical Center; N.A. Shadick, MD, MPH; M.L. Frits, BA; C.K. Iannaccone, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; T.K. Kvien, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; M.E. Weinblatt, MD, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; D.H. Solomon, MD, MPH, Division of Rheumatology, and Immunology and Allergy, and Division of Pharmacoepidemiology, Brigham and Women’s Hospital. Address correspondence to Dr. M.D. Mjaavatten, Department of Rheumatology, Diakonhjemmet Hospital, P.O. Box 23, Vinderen, 0319 Oslo, Norway. E-mail: maria_mjaavatten@hotmail.com. Accepted for publication August 26, 2014.
Michael E. Weinblatt
From the Division of Rheumatology, Immunology and Allergy, and the Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Boston, Massachusetts, USA; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria; Department of Rheumatology, Kameda Medical Center, Kamogawa, Chiba Prefecture, Japan. Dr. Solomon is supported by a mentoring award from the US National Institutes of Health (K24 AR055989). The Brigham and Women’s Hospital Rheumatoid Arthritis Sequential Study receives support from Bristol Myers Squibb, Medimmune, and Crescendo Bioscience. M.D. Mjaavatten, MD, PhD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; H. Radner, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna; K. Yoshida, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Kameda Medical Center; N.A. Shadick, MD, MPH; M.L. Frits, BA; C.K. Iannaccone, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; T.K. Kvien, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; M.E. Weinblatt, MD, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; D.H. Solomon, MD, MPH, Division of Rheumatology, and Immunology and Allergy, and Division of Pharmacoepidemiology, Brigham and Women’s Hospital. Address correspondence to Dr. M.D. Mjaavatten, Department of Rheumatology, Diakonhjemmet Hospital, P.O. Box 23, Vinderen, 0319 Oslo, Norway. E-mail: maria_mjaavatten@hotmail.com. Accepted for publication August 26, 2014.
Daniel H. Solomon
From the Division of Rheumatology, Immunology and Allergy, and the Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Boston, Massachusetts, USA; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria; Department of Rheumatology, Kameda Medical Center, Kamogawa, Chiba Prefecture, Japan. Dr. Solomon is supported by a mentoring award from the US National Institutes of Health (K24 AR055989). The Brigham and Women’s Hospital Rheumatoid Arthritis Sequential Study receives support from Bristol Myers Squibb, Medimmune, and Crescendo Bioscience. M.D. Mjaavatten, MD, PhD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Diakonhjemmet Hospital; H. Radner, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Internal Medicine III, Division of Rheumatology, Medical University Vienna; K. Yoshida, MD, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, and Department of Rheumatology, Kameda Medical Center; N.A. Shadick, MD, MPH; M.L. Frits, BA; C.K. Iannaccone, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; T.K. Kvien, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; M.E. Weinblatt, MD, MPH, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital; D.H. Solomon, MD, MPH, Division of Rheumatology, and Immunology and Allergy, and Division of Pharmacoepidemiology, Brigham and Women’s Hospital. Address correspondence to Dr. M.D. Mjaavatten, Department of Rheumatology, Diakonhjemmet Hospital, P.O. Box 23, Vinderen, 0319 Oslo, Norway. E-mail: maria_mjaavatten@hotmail.com. Accepted for publication August 26, 2014.
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In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Inconsistent Treatment with Disease-modifying Antirheumatic Drugs: A Longitudinal Data Analysis
Maria D. Mjaavatten, Helga Radner, Kazuki Yoshida, Nancy A. Shadick, Michelle L. Frits, Christine K. Iannaccone, Tore K. Kvien, Michael E. Weinblatt, Daniel H. Solomon
The Journal of Rheumatology Oct 2014, jrheum.140306; DOI: 10.3899/jrheum.140306
Inconsistent Treatment with Disease-modifying Antirheumatic Drugs: A Longitudinal Data Analysis
Maria D. Mjaavatten, Helga Radner, Kazuki Yoshida, Nancy A. Shadick, Michelle L. Frits, Christine K. Iannaccone, Tore K. Kvien, Michael E. Weinblatt, Daniel H. Solomon
The Journal of Rheumatology Oct 2014, jrheum.140306; DOI: 10.3899/jrheum.140306