Research ArticleArticle
Efficacy and Safety of Intravenous Tanezumab for the Symptomatic Treatment of Osteoarthritis: 2 Randomized Controlled Trials versus Naproxen
Evan F. Ekman, Joseph S. Gimbel, Alfonso E. Bello, Michael D. Smith, David S. Keller, Karen M. Annis, Mark T. Brown, Christine R. West and Kenneth M. Verburg
The Journal of Rheumatology October 2014, jrheum.131294; DOI: https://doi.org/10.3899/jrheum.131294
Evan F. Ekman
From Appalachian Regional Orthopaedic and Sports Medicine, Boone, North Carolina; Phoenix Orthopedic Surgeons, Phoenix, Arizona; Illinois Bone and Joint Institute, Glenview, Illinois; Pfizer Inc., Groton, Connecticut, USA. Supported by Pfizer Inc. E.F. Ekman, MD, Appalachian Regional Orthopaedic and Sports Medicine; J.S. Gimbel, MD, Phoenix Orthopedic Surgeons; A.E. Bello, MD, MHS, Illinois Bone and Joint Institute; M.D. Smith, PhD; D.S. Keller, PhD; K.M. Annis, MPH; M.T. Brown, MD; C.R. West, PhD; K.M. Verburg, PhD, Pfizer Inc. Address correspondence to Dr. E. Ekman, Appalachian Regional Orthopaedic and Sports Medicine, 870 State Farm Road, Suite 100, Boone, North Carolina 28607, USA. E-mail: evanekman@earthlink.net. Accepted for publication July 24, 2014.
Joseph S. Gimbel
From Appalachian Regional Orthopaedic and Sports Medicine, Boone, North Carolina; Phoenix Orthopedic Surgeons, Phoenix, Arizona; Illinois Bone and Joint Institute, Glenview, Illinois; Pfizer Inc., Groton, Connecticut, USA. Supported by Pfizer Inc. E.F. Ekman, MD, Appalachian Regional Orthopaedic and Sports Medicine; J.S. Gimbel, MD, Phoenix Orthopedic Surgeons; A.E. Bello, MD, MHS, Illinois Bone and Joint Institute; M.D. Smith, PhD; D.S. Keller, PhD; K.M. Annis, MPH; M.T. Brown, MD; C.R. West, PhD; K.M. Verburg, PhD, Pfizer Inc. Address correspondence to Dr. E. Ekman, Appalachian Regional Orthopaedic and Sports Medicine, 870 State Farm Road, Suite 100, Boone, North Carolina 28607, USA. E-mail: evanekman@earthlink.net. Accepted for publication July 24, 2014.
Alfonso E. Bello
From Appalachian Regional Orthopaedic and Sports Medicine, Boone, North Carolina; Phoenix Orthopedic Surgeons, Phoenix, Arizona; Illinois Bone and Joint Institute, Glenview, Illinois; Pfizer Inc., Groton, Connecticut, USA. Supported by Pfizer Inc. E.F. Ekman, MD, Appalachian Regional Orthopaedic and Sports Medicine; J.S. Gimbel, MD, Phoenix Orthopedic Surgeons; A.E. Bello, MD, MHS, Illinois Bone and Joint Institute; M.D. Smith, PhD; D.S. Keller, PhD; K.M. Annis, MPH; M.T. Brown, MD; C.R. West, PhD; K.M. Verburg, PhD, Pfizer Inc. Address correspondence to Dr. E. Ekman, Appalachian Regional Orthopaedic and Sports Medicine, 870 State Farm Road, Suite 100, Boone, North Carolina 28607, USA. E-mail: evanekman@earthlink.net. Accepted for publication July 24, 2014.
Michael D. Smith
From Appalachian Regional Orthopaedic and Sports Medicine, Boone, North Carolina; Phoenix Orthopedic Surgeons, Phoenix, Arizona; Illinois Bone and Joint Institute, Glenview, Illinois; Pfizer Inc., Groton, Connecticut, USA. Supported by Pfizer Inc. E.F. Ekman, MD, Appalachian Regional Orthopaedic and Sports Medicine; J.S. Gimbel, MD, Phoenix Orthopedic Surgeons; A.E. Bello, MD, MHS, Illinois Bone and Joint Institute; M.D. Smith, PhD; D.S. Keller, PhD; K.M. Annis, MPH; M.T. Brown, MD; C.R. West, PhD; K.M. Verburg, PhD, Pfizer Inc. Address correspondence to Dr. E. Ekman, Appalachian Regional Orthopaedic and Sports Medicine, 870 State Farm Road, Suite 100, Boone, North Carolina 28607, USA. E-mail: evanekman@earthlink.net. Accepted for publication July 24, 2014.
David S. Keller
From Appalachian Regional Orthopaedic and Sports Medicine, Boone, North Carolina; Phoenix Orthopedic Surgeons, Phoenix, Arizona; Illinois Bone and Joint Institute, Glenview, Illinois; Pfizer Inc., Groton, Connecticut, USA. Supported by Pfizer Inc. E.F. Ekman, MD, Appalachian Regional Orthopaedic and Sports Medicine; J.S. Gimbel, MD, Phoenix Orthopedic Surgeons; A.E. Bello, MD, MHS, Illinois Bone and Joint Institute; M.D. Smith, PhD; D.S. Keller, PhD; K.M. Annis, MPH; M.T. Brown, MD; C.R. West, PhD; K.M. Verburg, PhD, Pfizer Inc. Address correspondence to Dr. E. Ekman, Appalachian Regional Orthopaedic and Sports Medicine, 870 State Farm Road, Suite 100, Boone, North Carolina 28607, USA. E-mail: evanekman@earthlink.net. Accepted for publication July 24, 2014.
Karen M. Annis
From Appalachian Regional Orthopaedic and Sports Medicine, Boone, North Carolina; Phoenix Orthopedic Surgeons, Phoenix, Arizona; Illinois Bone and Joint Institute, Glenview, Illinois; Pfizer Inc., Groton, Connecticut, USA. Supported by Pfizer Inc. E.F. Ekman, MD, Appalachian Regional Orthopaedic and Sports Medicine; J.S. Gimbel, MD, Phoenix Orthopedic Surgeons; A.E. Bello, MD, MHS, Illinois Bone and Joint Institute; M.D. Smith, PhD; D.S. Keller, PhD; K.M. Annis, MPH; M.T. Brown, MD; C.R. West, PhD; K.M. Verburg, PhD, Pfizer Inc. Address correspondence to Dr. E. Ekman, Appalachian Regional Orthopaedic and Sports Medicine, 870 State Farm Road, Suite 100, Boone, North Carolina 28607, USA. E-mail: evanekman@earthlink.net. Accepted for publication July 24, 2014.
Mark T. Brown
From Appalachian Regional Orthopaedic and Sports Medicine, Boone, North Carolina; Phoenix Orthopedic Surgeons, Phoenix, Arizona; Illinois Bone and Joint Institute, Glenview, Illinois; Pfizer Inc., Groton, Connecticut, USA. Supported by Pfizer Inc. E.F. Ekman, MD, Appalachian Regional Orthopaedic and Sports Medicine; J.S. Gimbel, MD, Phoenix Orthopedic Surgeons; A.E. Bello, MD, MHS, Illinois Bone and Joint Institute; M.D. Smith, PhD; D.S. Keller, PhD; K.M. Annis, MPH; M.T. Brown, MD; C.R. West, PhD; K.M. Verburg, PhD, Pfizer Inc. Address correspondence to Dr. E. Ekman, Appalachian Regional Orthopaedic and Sports Medicine, 870 State Farm Road, Suite 100, Boone, North Carolina 28607, USA. E-mail: evanekman@earthlink.net. Accepted for publication July 24, 2014.
Christine R. West
From Appalachian Regional Orthopaedic and Sports Medicine, Boone, North Carolina; Phoenix Orthopedic Surgeons, Phoenix, Arizona; Illinois Bone and Joint Institute, Glenview, Illinois; Pfizer Inc., Groton, Connecticut, USA. Supported by Pfizer Inc. E.F. Ekman, MD, Appalachian Regional Orthopaedic and Sports Medicine; J.S. Gimbel, MD, Phoenix Orthopedic Surgeons; A.E. Bello, MD, MHS, Illinois Bone and Joint Institute; M.D. Smith, PhD; D.S. Keller, PhD; K.M. Annis, MPH; M.T. Brown, MD; C.R. West, PhD; K.M. Verburg, PhD, Pfizer Inc. Address correspondence to Dr. E. Ekman, Appalachian Regional Orthopaedic and Sports Medicine, 870 State Farm Road, Suite 100, Boone, North Carolina 28607, USA. E-mail: evanekman@earthlink.net. Accepted for publication July 24, 2014.
Kenneth M. Verburg
From Appalachian Regional Orthopaedic and Sports Medicine, Boone, North Carolina; Phoenix Orthopedic Surgeons, Phoenix, Arizona; Illinois Bone and Joint Institute, Glenview, Illinois; Pfizer Inc., Groton, Connecticut, USA. Supported by Pfizer Inc. E.F. Ekman, MD, Appalachian Regional Orthopaedic and Sports Medicine; J.S. Gimbel, MD, Phoenix Orthopedic Surgeons; A.E. Bello, MD, MHS, Illinois Bone and Joint Institute; M.D. Smith, PhD; D.S. Keller, PhD; K.M. Annis, MPH; M.T. Brown, MD; C.R. West, PhD; K.M. Verburg, PhD, Pfizer Inc. Address correspondence to Dr. E. Ekman, Appalachian Regional Orthopaedic and Sports Medicine, 870 State Farm Road, Suite 100, Boone, North Carolina 28607, USA. E-mail: evanekman@earthlink.net. Accepted for publication July 24, 2014.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 3
1 Mar 2024
Efficacy and Safety of Intravenous Tanezumab for the Symptomatic Treatment of Osteoarthritis: 2 Randomized Controlled Trials versus Naproxen
Evan F. Ekman, Joseph S. Gimbel, Alfonso E. Bello, Michael D. Smith, David S. Keller, Karen M. Annis, Mark T. Brown, Christine R. West, Kenneth M. Verburg
The Journal of Rheumatology Oct 2014, jrheum.131294; DOI: 10.3899/jrheum.131294
Efficacy and Safety of Intravenous Tanezumab for the Symptomatic Treatment of Osteoarthritis: 2 Randomized Controlled Trials versus Naproxen
Evan F. Ekman, Joseph S. Gimbel, Alfonso E. Bello, Michael D. Smith, David S. Keller, Karen M. Annis, Mark T. Brown, Christine R. West, Kenneth M. Verburg
The Journal of Rheumatology Oct 2014, jrheum.131294; DOI: 10.3899/jrheum.131294