Research ArticleArticle
Determinants of Erythrocyte Methotrexate Polyglutamate Levels in Rheumatoid Arthritis
Ethan den Boer, Maurits C.J.F. de Rotte, Saskia M.F. Pluijm, Sandra G. Heil, Johanna M. Hazes and Robert de Jonge
The Journal of Rheumatology September 2014, jrheum.131290; DOI: https://doi.org/10.3899/jrheum.131290
Ethan den Boer
From the Department of Clinical Chemistry; Department of Rheumatology; Department of Pediatric Hemato-Oncology; Erasmus University Medical Center, Rotterdam, the Netherlands. Supported by treatment in Rotterdam Early Arthritis Cohort (tREACH): Unrestricted grant from Pfizer bv. (0881-102217). RDJ: Dutch Arthritis Association (06-02-402 and 09-1-402). E. den Boer, MSc; M.C.J.F. de Rotte, PharmD; S.G. Heil, PhD; R. de Jonge, PhD, Department of Clinical Chemistry; J.M. Hazes, MD, PhD, Department of Rheumatology; S.M.F. Pluijm, PhD, Department of Pediatric Hemato-Oncology, Erasmus University Medical Center.Address correspondence to Dr. R. de Jonge, Erasmus University Medical Center, Department of Clinical Chemistry, ‘s-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. E-mail: r.dejonge@erasmusmc.nl Accepted for publication July 8, 2014.
Maurits C.J.F. de Rotte
From the Department of Clinical Chemistry; Department of Rheumatology; Department of Pediatric Hemato-Oncology; Erasmus University Medical Center, Rotterdam, the Netherlands. Supported by treatment in Rotterdam Early Arthritis Cohort (tREACH): Unrestricted grant from Pfizer bv. (0881-102217). RDJ: Dutch Arthritis Association (06-02-402 and 09-1-402). E. den Boer, MSc; M.C.J.F. de Rotte, PharmD; S.G. Heil, PhD; R. de Jonge, PhD, Department of Clinical Chemistry; J.M. Hazes, MD, PhD, Department of Rheumatology; S.M.F. Pluijm, PhD, Department of Pediatric Hemato-Oncology, Erasmus University Medical Center.Address correspondence to Dr. R. de Jonge, Erasmus University Medical Center, Department of Clinical Chemistry, ‘s-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. E-mail: r.dejonge@erasmusmc.nl Accepted for publication July 8, 2014.
Saskia M.F. Pluijm
From the Department of Clinical Chemistry; Department of Rheumatology; Department of Pediatric Hemato-Oncology; Erasmus University Medical Center, Rotterdam, the Netherlands. Supported by treatment in Rotterdam Early Arthritis Cohort (tREACH): Unrestricted grant from Pfizer bv. (0881-102217). RDJ: Dutch Arthritis Association (06-02-402 and 09-1-402). E. den Boer, MSc; M.C.J.F. de Rotte, PharmD; S.G. Heil, PhD; R. de Jonge, PhD, Department of Clinical Chemistry; J.M. Hazes, MD, PhD, Department of Rheumatology; S.M.F. Pluijm, PhD, Department of Pediatric Hemato-Oncology, Erasmus University Medical Center.Address correspondence to Dr. R. de Jonge, Erasmus University Medical Center, Department of Clinical Chemistry, ‘s-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. E-mail: r.dejonge@erasmusmc.nl Accepted for publication July 8, 2014.
Sandra G. Heil
From the Department of Clinical Chemistry; Department of Rheumatology; Department of Pediatric Hemato-Oncology; Erasmus University Medical Center, Rotterdam, the Netherlands. Supported by treatment in Rotterdam Early Arthritis Cohort (tREACH): Unrestricted grant from Pfizer bv. (0881-102217). RDJ: Dutch Arthritis Association (06-02-402 and 09-1-402). E. den Boer, MSc; M.C.J.F. de Rotte, PharmD; S.G. Heil, PhD; R. de Jonge, PhD, Department of Clinical Chemistry; J.M. Hazes, MD, PhD, Department of Rheumatology; S.M.F. Pluijm, PhD, Department of Pediatric Hemato-Oncology, Erasmus University Medical Center.Address correspondence to Dr. R. de Jonge, Erasmus University Medical Center, Department of Clinical Chemistry, ‘s-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. E-mail: r.dejonge@erasmusmc.nl Accepted for publication July 8, 2014.
Johanna M. Hazes
From the Department of Clinical Chemistry; Department of Rheumatology; Department of Pediatric Hemato-Oncology; Erasmus University Medical Center, Rotterdam, the Netherlands. Supported by treatment in Rotterdam Early Arthritis Cohort (tREACH): Unrestricted grant from Pfizer bv. (0881-102217). RDJ: Dutch Arthritis Association (06-02-402 and 09-1-402). E. den Boer, MSc; M.C.J.F. de Rotte, PharmD; S.G. Heil, PhD; R. de Jonge, PhD, Department of Clinical Chemistry; J.M. Hazes, MD, PhD, Department of Rheumatology; S.M.F. Pluijm, PhD, Department of Pediatric Hemato-Oncology, Erasmus University Medical Center.Address correspondence to Dr. R. de Jonge, Erasmus University Medical Center, Department of Clinical Chemistry, ‘s-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. E-mail: r.dejonge@erasmusmc.nl Accepted for publication July 8, 2014.
Robert de Jonge
From the Department of Clinical Chemistry; Department of Rheumatology; Department of Pediatric Hemato-Oncology; Erasmus University Medical Center, Rotterdam, the Netherlands. Supported by treatment in Rotterdam Early Arthritis Cohort (tREACH): Unrestricted grant from Pfizer bv. (0881-102217). RDJ: Dutch Arthritis Association (06-02-402 and 09-1-402). E. den Boer, MSc; M.C.J.F. de Rotte, PharmD; S.G. Heil, PhD; R. de Jonge, PhD, Department of Clinical Chemistry; J.M. Hazes, MD, PhD, Department of Rheumatology; S.M.F. Pluijm, PhD, Department of Pediatric Hemato-Oncology, Erasmus University Medical Center.Address correspondence to Dr. R. de Jonge, Erasmus University Medical Center, Department of Clinical Chemistry, ‘s-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. E-mail: r.dejonge@erasmusmc.nl Accepted for publication July 8, 2014.
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In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Determinants of Erythrocyte Methotrexate Polyglutamate Levels in Rheumatoid Arthritis
Ethan den Boer, Maurits C.J.F. de Rotte, Saskia M.F. Pluijm, Sandra G. Heil, Johanna M. Hazes, Robert de Jonge
The Journal of Rheumatology Sep 2014, jrheum.131290; DOI: 10.3899/jrheum.131290