Research ArticleArticle
Adipose Depots, Not Disease-related Factors, Account for Skeletal Muscle Insulin Sensitivity in Established and Treated Rheumatoid Arthritis
Hiba AbouAssi, K. Noelle Tune, Brian Gilmore, Lori A. Bateman, Gary McDaniel, Michael Muehlbauer, Janet L. Huebner, Helen M. Hoenig, Virginia B. Kraus, E. William St. Clair, William E. Kraus and Kim M. Huffman
The Journal of Rheumatology July 2014, jrheum.140224; DOI: https://doi.org/10.3899/jrheum.140224
Hiba AbouAssi
From the Divisions of Endocrinology, Rheumatology and Immunology, Cardiology, Geriatrics, Department of Medicine and Duke Molecular Physiology Institute, Duke University Medical Center; Durham Veterans Affairs Medical Center, Durham, North Carolina, USA. Supported by US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases K23AR054904, an American College of Rheumatology-Rheumatology Research Foundation (ACR-RRF)/Association for Specialty Professors (ASP) Junior Career Development Award in Geriatric Medicine funded by Atlantic Philanthropies, ACR-RRF, John A. Hartford Foundation and ASP, and an Early Career Development Award from the Central Society for Clinical Research. H. AbouAssi, MD, Division of Endocrinology; K.N. Tune, BA, Division of Rheumatology and Immunology; B. Gilmore, BS; L.A. Bateman, MS, Division of Cardiology; G. McDaniel, PA, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; M. Muehlbauer, PhD; J.L. Huebner, MS, Duke Molecular Physiology Institute, Duke University Medical Center; H.M. Hoenig, MD, Division of Geriatrics, Department of Medicine, Duke University Medical Center, Veterans Affairs Medical Center; V.B. Kraus, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; E.W. St. Clair, MD, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; W.E. Kraus, MD, Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; K.M. Huffman, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, and Veterans Affairs Medical Center. Address correspondence to Dr. K.M. Huffman, Duke Molecular Physiology Institute, 300 N. Duke St., Durham, North Carolina 27701, USA. E-mail: kim.huffman@duke.edu. Accepted for publication April 11, 2014.
K. Noelle Tune
From the Divisions of Endocrinology, Rheumatology and Immunology, Cardiology, Geriatrics, Department of Medicine and Duke Molecular Physiology Institute, Duke University Medical Center; Durham Veterans Affairs Medical Center, Durham, North Carolina, USA. Supported by US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases K23AR054904, an American College of Rheumatology-Rheumatology Research Foundation (ACR-RRF)/Association for Specialty Professors (ASP) Junior Career Development Award in Geriatric Medicine funded by Atlantic Philanthropies, ACR-RRF, John A. Hartford Foundation and ASP, and an Early Career Development Award from the Central Society for Clinical Research. H. AbouAssi, MD, Division of Endocrinology; K.N. Tune, BA, Division of Rheumatology and Immunology; B. Gilmore, BS; L.A. Bateman, MS, Division of Cardiology; G. McDaniel, PA, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; M. Muehlbauer, PhD; J.L. Huebner, MS, Duke Molecular Physiology Institute, Duke University Medical Center; H.M. Hoenig, MD, Division of Geriatrics, Department of Medicine, Duke University Medical Center, Veterans Affairs Medical Center; V.B. Kraus, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; E.W. St. Clair, MD, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; W.E. Kraus, MD, Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; K.M. Huffman, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, and Veterans Affairs Medical Center. Address correspondence to Dr. K.M. Huffman, Duke Molecular Physiology Institute, 300 N. Duke St., Durham, North Carolina 27701, USA. E-mail: kim.huffman@duke.edu. Accepted for publication April 11, 2014.
Brian Gilmore
From the Divisions of Endocrinology, Rheumatology and Immunology, Cardiology, Geriatrics, Department of Medicine and Duke Molecular Physiology Institute, Duke University Medical Center; Durham Veterans Affairs Medical Center, Durham, North Carolina, USA. Supported by US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases K23AR054904, an American College of Rheumatology-Rheumatology Research Foundation (ACR-RRF)/Association for Specialty Professors (ASP) Junior Career Development Award in Geriatric Medicine funded by Atlantic Philanthropies, ACR-RRF, John A. Hartford Foundation and ASP, and an Early Career Development Award from the Central Society for Clinical Research. H. AbouAssi, MD, Division of Endocrinology; K.N. Tune, BA, Division of Rheumatology and Immunology; B. Gilmore, BS; L.A. Bateman, MS, Division of Cardiology; G. McDaniel, PA, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; M. Muehlbauer, PhD; J.L. Huebner, MS, Duke Molecular Physiology Institute, Duke University Medical Center; H.M. Hoenig, MD, Division of Geriatrics, Department of Medicine, Duke University Medical Center, Veterans Affairs Medical Center; V.B. Kraus, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; E.W. St. Clair, MD, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; W.E. Kraus, MD, Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; K.M. Huffman, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, and Veterans Affairs Medical Center. Address correspondence to Dr. K.M. Huffman, Duke Molecular Physiology Institute, 300 N. Duke St., Durham, North Carolina 27701, USA. E-mail: kim.huffman@duke.edu. Accepted for publication April 11, 2014.
Lori A. Bateman
From the Divisions of Endocrinology, Rheumatology and Immunology, Cardiology, Geriatrics, Department of Medicine and Duke Molecular Physiology Institute, Duke University Medical Center; Durham Veterans Affairs Medical Center, Durham, North Carolina, USA. Supported by US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases K23AR054904, an American College of Rheumatology-Rheumatology Research Foundation (ACR-RRF)/Association for Specialty Professors (ASP) Junior Career Development Award in Geriatric Medicine funded by Atlantic Philanthropies, ACR-RRF, John A. Hartford Foundation and ASP, and an Early Career Development Award from the Central Society for Clinical Research. H. AbouAssi, MD, Division of Endocrinology; K.N. Tune, BA, Division of Rheumatology and Immunology; B. Gilmore, BS; L.A. Bateman, MS, Division of Cardiology; G. McDaniel, PA, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; M. Muehlbauer, PhD; J.L. Huebner, MS, Duke Molecular Physiology Institute, Duke University Medical Center; H.M. Hoenig, MD, Division of Geriatrics, Department of Medicine, Duke University Medical Center, Veterans Affairs Medical Center; V.B. Kraus, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; E.W. St. Clair, MD, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; W.E. Kraus, MD, Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; K.M. Huffman, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, and Veterans Affairs Medical Center. Address correspondence to Dr. K.M. Huffman, Duke Molecular Physiology Institute, 300 N. Duke St., Durham, North Carolina 27701, USA. E-mail: kim.huffman@duke.edu. Accepted for publication April 11, 2014.
Gary McDaniel
From the Divisions of Endocrinology, Rheumatology and Immunology, Cardiology, Geriatrics, Department of Medicine and Duke Molecular Physiology Institute, Duke University Medical Center; Durham Veterans Affairs Medical Center, Durham, North Carolina, USA. Supported by US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases K23AR054904, an American College of Rheumatology-Rheumatology Research Foundation (ACR-RRF)/Association for Specialty Professors (ASP) Junior Career Development Award in Geriatric Medicine funded by Atlantic Philanthropies, ACR-RRF, John A. Hartford Foundation and ASP, and an Early Career Development Award from the Central Society for Clinical Research. H. AbouAssi, MD, Division of Endocrinology; K.N. Tune, BA, Division of Rheumatology and Immunology; B. Gilmore, BS; L.A. Bateman, MS, Division of Cardiology; G. McDaniel, PA, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; M. Muehlbauer, PhD; J.L. Huebner, MS, Duke Molecular Physiology Institute, Duke University Medical Center; H.M. Hoenig, MD, Division of Geriatrics, Department of Medicine, Duke University Medical Center, Veterans Affairs Medical Center; V.B. Kraus, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; E.W. St. Clair, MD, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; W.E. Kraus, MD, Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; K.M. Huffman, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, and Veterans Affairs Medical Center. Address correspondence to Dr. K.M. Huffman, Duke Molecular Physiology Institute, 300 N. Duke St., Durham, North Carolina 27701, USA. E-mail: kim.huffman@duke.edu. Accepted for publication April 11, 2014.
Michael Muehlbauer
From the Divisions of Endocrinology, Rheumatology and Immunology, Cardiology, Geriatrics, Department of Medicine and Duke Molecular Physiology Institute, Duke University Medical Center; Durham Veterans Affairs Medical Center, Durham, North Carolina, USA. Supported by US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases K23AR054904, an American College of Rheumatology-Rheumatology Research Foundation (ACR-RRF)/Association for Specialty Professors (ASP) Junior Career Development Award in Geriatric Medicine funded by Atlantic Philanthropies, ACR-RRF, John A. Hartford Foundation and ASP, and an Early Career Development Award from the Central Society for Clinical Research. H. AbouAssi, MD, Division of Endocrinology; K.N. Tune, BA, Division of Rheumatology and Immunology; B. Gilmore, BS; L.A. Bateman, MS, Division of Cardiology; G. McDaniel, PA, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; M. Muehlbauer, PhD; J.L. Huebner, MS, Duke Molecular Physiology Institute, Duke University Medical Center; H.M. Hoenig, MD, Division of Geriatrics, Department of Medicine, Duke University Medical Center, Veterans Affairs Medical Center; V.B. Kraus, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; E.W. St. Clair, MD, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; W.E. Kraus, MD, Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; K.M. Huffman, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, and Veterans Affairs Medical Center. Address correspondence to Dr. K.M. Huffman, Duke Molecular Physiology Institute, 300 N. Duke St., Durham, North Carolina 27701, USA. E-mail: kim.huffman@duke.edu. Accepted for publication April 11, 2014.
Janet L. Huebner
From the Divisions of Endocrinology, Rheumatology and Immunology, Cardiology, Geriatrics, Department of Medicine and Duke Molecular Physiology Institute, Duke University Medical Center; Durham Veterans Affairs Medical Center, Durham, North Carolina, USA. Supported by US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases K23AR054904, an American College of Rheumatology-Rheumatology Research Foundation (ACR-RRF)/Association for Specialty Professors (ASP) Junior Career Development Award in Geriatric Medicine funded by Atlantic Philanthropies, ACR-RRF, John A. Hartford Foundation and ASP, and an Early Career Development Award from the Central Society for Clinical Research. H. AbouAssi, MD, Division of Endocrinology; K.N. Tune, BA, Division of Rheumatology and Immunology; B. Gilmore, BS; L.A. Bateman, MS, Division of Cardiology; G. McDaniel, PA, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; M. Muehlbauer, PhD; J.L. Huebner, MS, Duke Molecular Physiology Institute, Duke University Medical Center; H.M. Hoenig, MD, Division of Geriatrics, Department of Medicine, Duke University Medical Center, Veterans Affairs Medical Center; V.B. Kraus, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; E.W. St. Clair, MD, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; W.E. Kraus, MD, Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; K.M. Huffman, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, and Veterans Affairs Medical Center. Address correspondence to Dr. K.M. Huffman, Duke Molecular Physiology Institute, 300 N. Duke St., Durham, North Carolina 27701, USA. E-mail: kim.huffman@duke.edu. Accepted for publication April 11, 2014.
Helen M. Hoenig
From the Divisions of Endocrinology, Rheumatology and Immunology, Cardiology, Geriatrics, Department of Medicine and Duke Molecular Physiology Institute, Duke University Medical Center; Durham Veterans Affairs Medical Center, Durham, North Carolina, USA. Supported by US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases K23AR054904, an American College of Rheumatology-Rheumatology Research Foundation (ACR-RRF)/Association for Specialty Professors (ASP) Junior Career Development Award in Geriatric Medicine funded by Atlantic Philanthropies, ACR-RRF, John A. Hartford Foundation and ASP, and an Early Career Development Award from the Central Society for Clinical Research. H. AbouAssi, MD, Division of Endocrinology; K.N. Tune, BA, Division of Rheumatology and Immunology; B. Gilmore, BS; L.A. Bateman, MS, Division of Cardiology; G. McDaniel, PA, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; M. Muehlbauer, PhD; J.L. Huebner, MS, Duke Molecular Physiology Institute, Duke University Medical Center; H.M. Hoenig, MD, Division of Geriatrics, Department of Medicine, Duke University Medical Center, Veterans Affairs Medical Center; V.B. Kraus, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; E.W. St. Clair, MD, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; W.E. Kraus, MD, Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; K.M. Huffman, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, and Veterans Affairs Medical Center. Address correspondence to Dr. K.M. Huffman, Duke Molecular Physiology Institute, 300 N. Duke St., Durham, North Carolina 27701, USA. E-mail: kim.huffman@duke.edu. Accepted for publication April 11, 2014.
Virginia B. Kraus
From the Divisions of Endocrinology, Rheumatology and Immunology, Cardiology, Geriatrics, Department of Medicine and Duke Molecular Physiology Institute, Duke University Medical Center; Durham Veterans Affairs Medical Center, Durham, North Carolina, USA. Supported by US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases K23AR054904, an American College of Rheumatology-Rheumatology Research Foundation (ACR-RRF)/Association for Specialty Professors (ASP) Junior Career Development Award in Geriatric Medicine funded by Atlantic Philanthropies, ACR-RRF, John A. Hartford Foundation and ASP, and an Early Career Development Award from the Central Society for Clinical Research. H. AbouAssi, MD, Division of Endocrinology; K.N. Tune, BA, Division of Rheumatology and Immunology; B. Gilmore, BS; L.A. Bateman, MS, Division of Cardiology; G. McDaniel, PA, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; M. Muehlbauer, PhD; J.L. Huebner, MS, Duke Molecular Physiology Institute, Duke University Medical Center; H.M. Hoenig, MD, Division of Geriatrics, Department of Medicine, Duke University Medical Center, Veterans Affairs Medical Center; V.B. Kraus, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; E.W. St. Clair, MD, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; W.E. Kraus, MD, Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; K.M. Huffman, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, and Veterans Affairs Medical Center. Address correspondence to Dr. K.M. Huffman, Duke Molecular Physiology Institute, 300 N. Duke St., Durham, North Carolina 27701, USA. E-mail: kim.huffman@duke.edu. Accepted for publication April 11, 2014.
E. William St. Clair
From the Divisions of Endocrinology, Rheumatology and Immunology, Cardiology, Geriatrics, Department of Medicine and Duke Molecular Physiology Institute, Duke University Medical Center; Durham Veterans Affairs Medical Center, Durham, North Carolina, USA. Supported by US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases K23AR054904, an American College of Rheumatology-Rheumatology Research Foundation (ACR-RRF)/Association for Specialty Professors (ASP) Junior Career Development Award in Geriatric Medicine funded by Atlantic Philanthropies, ACR-RRF, John A. Hartford Foundation and ASP, and an Early Career Development Award from the Central Society for Clinical Research. H. AbouAssi, MD, Division of Endocrinology; K.N. Tune, BA, Division of Rheumatology and Immunology; B. Gilmore, BS; L.A. Bateman, MS, Division of Cardiology; G. McDaniel, PA, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; M. Muehlbauer, PhD; J.L. Huebner, MS, Duke Molecular Physiology Institute, Duke University Medical Center; H.M. Hoenig, MD, Division of Geriatrics, Department of Medicine, Duke University Medical Center, Veterans Affairs Medical Center; V.B. Kraus, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; E.W. St. Clair, MD, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; W.E. Kraus, MD, Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; K.M. Huffman, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, and Veterans Affairs Medical Center. Address correspondence to Dr. K.M. Huffman, Duke Molecular Physiology Institute, 300 N. Duke St., Durham, North Carolina 27701, USA. E-mail: kim.huffman@duke.edu. Accepted for publication April 11, 2014.
William E. Kraus
From the Divisions of Endocrinology, Rheumatology and Immunology, Cardiology, Geriatrics, Department of Medicine and Duke Molecular Physiology Institute, Duke University Medical Center; Durham Veterans Affairs Medical Center, Durham, North Carolina, USA. Supported by US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases K23AR054904, an American College of Rheumatology-Rheumatology Research Foundation (ACR-RRF)/Association for Specialty Professors (ASP) Junior Career Development Award in Geriatric Medicine funded by Atlantic Philanthropies, ACR-RRF, John A. Hartford Foundation and ASP, and an Early Career Development Award from the Central Society for Clinical Research. H. AbouAssi, MD, Division of Endocrinology; K.N. Tune, BA, Division of Rheumatology and Immunology; B. Gilmore, BS; L.A. Bateman, MS, Division of Cardiology; G. McDaniel, PA, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; M. Muehlbauer, PhD; J.L. Huebner, MS, Duke Molecular Physiology Institute, Duke University Medical Center; H.M. Hoenig, MD, Division of Geriatrics, Department of Medicine, Duke University Medical Center, Veterans Affairs Medical Center; V.B. Kraus, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; E.W. St. Clair, MD, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; W.E. Kraus, MD, Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; K.M. Huffman, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, and Veterans Affairs Medical Center. Address correspondence to Dr. K.M. Huffman, Duke Molecular Physiology Institute, 300 N. Duke St., Durham, North Carolina 27701, USA. E-mail: kim.huffman@duke.edu. Accepted for publication April 11, 2014.
Kim M. Huffman
From the Divisions of Endocrinology, Rheumatology and Immunology, Cardiology, Geriatrics, Department of Medicine and Duke Molecular Physiology Institute, Duke University Medical Center; Durham Veterans Affairs Medical Center, Durham, North Carolina, USA. Supported by US National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases K23AR054904, an American College of Rheumatology-Rheumatology Research Foundation (ACR-RRF)/Association for Specialty Professors (ASP) Junior Career Development Award in Geriatric Medicine funded by Atlantic Philanthropies, ACR-RRF, John A. Hartford Foundation and ASP, and an Early Career Development Award from the Central Society for Clinical Research. H. AbouAssi, MD, Division of Endocrinology; K.N. Tune, BA, Division of Rheumatology and Immunology; B. Gilmore, BS; L.A. Bateman, MS, Division of Cardiology; G. McDaniel, PA, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; M. Muehlbauer, PhD; J.L. Huebner, MS, Duke Molecular Physiology Institute, Duke University Medical Center; H.M. Hoenig, MD, Division of Geriatrics, Department of Medicine, Duke University Medical Center, Veterans Affairs Medical Center; V.B. Kraus, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; E.W. St. Clair, MD, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; W.E. Kraus, MD, Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center; K.M. Huffman, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, and Veterans Affairs Medical Center. Address correspondence to Dr. K.M. Huffman, Duke Molecular Physiology Institute, 300 N. Duke St., Durham, North Carolina 27701, USA. E-mail: kim.huffman@duke.edu. Accepted for publication April 11, 2014.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Adipose Depots, Not Disease-related Factors, Account for Skeletal Muscle Insulin Sensitivity in Established and Treated Rheumatoid Arthritis
Hiba AbouAssi, K. Noelle Tune, Brian Gilmore, Lori A. Bateman, Gary McDaniel, Michael Muehlbauer, Janet L. Huebner, Helen M. Hoenig, Virginia B. Kraus, E. William St. Clair, William E. Kraus, Kim M. Huffman
The Journal of Rheumatology Jul 2014, jrheum.140224; DOI: 10.3899/jrheum.140224
Adipose Depots, Not Disease-related Factors, Account for Skeletal Muscle Insulin Sensitivity in Established and Treated Rheumatoid Arthritis
Hiba AbouAssi, K. Noelle Tune, Brian Gilmore, Lori A. Bateman, Gary McDaniel, Michael Muehlbauer, Janet L. Huebner, Helen M. Hoenig, Virginia B. Kraus, E. William St. Clair, William E. Kraus, Kim M. Huffman
The Journal of Rheumatology Jul 2014, jrheum.140224; DOI: 10.3899/jrheum.140224