Research ArticleArticle
Discrepancy Between Clinical and Radiological Responses to Tocilizumab Treatment in Patients with Systemic-onset Juvenile Idiopathic Arthritis
Chie Aoki, Yutaka Inaba, Hyonmin Choe, Utako Kaneko, Ryoki Hara, Takako Miyamae, Tomoyuki Imagawa, Masaaki Mori, Mari S. Oba, Shumpei Yokota and Tomoyuki Saito
The Journal of Rheumatology May 2014, jrheum.130924; DOI: https://doi.org/10.3899/jrheum.130924
Chie Aoki
From the Department of Orthopedic Surgery, the Department of Pediatrics, and the Department of Biostatistics and Epidemiology, Yokohama City University, Yokohama, Japan. Dr. Yokota has received consulting and speaking fees from Chugai Pharmaceutical. Drs. Yokota and Miyamae are co-inventors of a patent for juvenile arthritis treatment. C. Aoki, MD; Y. Inaba, MD, PhD, Associate Professor; H. Choe, MD, PhD, Department of Orthopedic Surgery; U. Kaneko, MD; R. Hara, MD, PhD; T. Miyamae, MD, PhD; T. Imagawa, MD, PhD; M. Mori, MD, PhD, Associate Professor, Department of Pediatrics; M.S. Oba, Department of Biostatistics and Epidemiology; S. Yokota, MD, Professor of Pediatrics, Department of Pediatrics; T. Saito, MD, Professor of Orthopedics, Department of Orthopedic Surgery, Yokohama City University. Address correspondence to Dr. Y. Inaba, Department of Orthopedic Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. E-mail: yute0131@med.yokohama-cu.ac.jp. Accepted for publication February 20, 2014.
Yutaka Inaba
From the Department of Orthopedic Surgery, the Department of Pediatrics, and the Department of Biostatistics and Epidemiology, Yokohama City University, Yokohama, Japan. Dr. Yokota has received consulting and speaking fees from Chugai Pharmaceutical. Drs. Yokota and Miyamae are co-inventors of a patent for juvenile arthritis treatment. C. Aoki, MD; Y. Inaba, MD, PhD, Associate Professor; H. Choe, MD, PhD, Department of Orthopedic Surgery; U. Kaneko, MD; R. Hara, MD, PhD; T. Miyamae, MD, PhD; T. Imagawa, MD, PhD; M. Mori, MD, PhD, Associate Professor, Department of Pediatrics; M.S. Oba, Department of Biostatistics and Epidemiology; S. Yokota, MD, Professor of Pediatrics, Department of Pediatrics; T. Saito, MD, Professor of Orthopedics, Department of Orthopedic Surgery, Yokohama City University. Address correspondence to Dr. Y. Inaba, Department of Orthopedic Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. E-mail: yute0131@med.yokohama-cu.ac.jp. Accepted for publication February 20, 2014.
Hyonmin Choe
From the Department of Orthopedic Surgery, the Department of Pediatrics, and the Department of Biostatistics and Epidemiology, Yokohama City University, Yokohama, Japan. Dr. Yokota has received consulting and speaking fees from Chugai Pharmaceutical. Drs. Yokota and Miyamae are co-inventors of a patent for juvenile arthritis treatment. C. Aoki, MD; Y. Inaba, MD, PhD, Associate Professor; H. Choe, MD, PhD, Department of Orthopedic Surgery; U. Kaneko, MD; R. Hara, MD, PhD; T. Miyamae, MD, PhD; T. Imagawa, MD, PhD; M. Mori, MD, PhD, Associate Professor, Department of Pediatrics; M.S. Oba, Department of Biostatistics and Epidemiology; S. Yokota, MD, Professor of Pediatrics, Department of Pediatrics; T. Saito, MD, Professor of Orthopedics, Department of Orthopedic Surgery, Yokohama City University. Address correspondence to Dr. Y. Inaba, Department of Orthopedic Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. E-mail: yute0131@med.yokohama-cu.ac.jp. Accepted for publication February 20, 2014.
Utako Kaneko
From the Department of Orthopedic Surgery, the Department of Pediatrics, and the Department of Biostatistics and Epidemiology, Yokohama City University, Yokohama, Japan. Dr. Yokota has received consulting and speaking fees from Chugai Pharmaceutical. Drs. Yokota and Miyamae are co-inventors of a patent for juvenile arthritis treatment. C. Aoki, MD; Y. Inaba, MD, PhD, Associate Professor; H. Choe, MD, PhD, Department of Orthopedic Surgery; U. Kaneko, MD; R. Hara, MD, PhD; T. Miyamae, MD, PhD; T. Imagawa, MD, PhD; M. Mori, MD, PhD, Associate Professor, Department of Pediatrics; M.S. Oba, Department of Biostatistics and Epidemiology; S. Yokota, MD, Professor of Pediatrics, Department of Pediatrics; T. Saito, MD, Professor of Orthopedics, Department of Orthopedic Surgery, Yokohama City University. Address correspondence to Dr. Y. Inaba, Department of Orthopedic Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. E-mail: yute0131@med.yokohama-cu.ac.jp. Accepted for publication February 20, 2014.
Ryoki Hara
From the Department of Orthopedic Surgery, the Department of Pediatrics, and the Department of Biostatistics and Epidemiology, Yokohama City University, Yokohama, Japan. Dr. Yokota has received consulting and speaking fees from Chugai Pharmaceutical. Drs. Yokota and Miyamae are co-inventors of a patent for juvenile arthritis treatment. C. Aoki, MD; Y. Inaba, MD, PhD, Associate Professor; H. Choe, MD, PhD, Department of Orthopedic Surgery; U. Kaneko, MD; R. Hara, MD, PhD; T. Miyamae, MD, PhD; T. Imagawa, MD, PhD; M. Mori, MD, PhD, Associate Professor, Department of Pediatrics; M.S. Oba, Department of Biostatistics and Epidemiology; S. Yokota, MD, Professor of Pediatrics, Department of Pediatrics; T. Saito, MD, Professor of Orthopedics, Department of Orthopedic Surgery, Yokohama City University. Address correspondence to Dr. Y. Inaba, Department of Orthopedic Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. E-mail: yute0131@med.yokohama-cu.ac.jp. Accepted for publication February 20, 2014.
Takako Miyamae
From the Department of Orthopedic Surgery, the Department of Pediatrics, and the Department of Biostatistics and Epidemiology, Yokohama City University, Yokohama, Japan. Dr. Yokota has received consulting and speaking fees from Chugai Pharmaceutical. Drs. Yokota and Miyamae are co-inventors of a patent for juvenile arthritis treatment. C. Aoki, MD; Y. Inaba, MD, PhD, Associate Professor; H. Choe, MD, PhD, Department of Orthopedic Surgery; U. Kaneko, MD; R. Hara, MD, PhD; T. Miyamae, MD, PhD; T. Imagawa, MD, PhD; M. Mori, MD, PhD, Associate Professor, Department of Pediatrics; M.S. Oba, Department of Biostatistics and Epidemiology; S. Yokota, MD, Professor of Pediatrics, Department of Pediatrics; T. Saito, MD, Professor of Orthopedics, Department of Orthopedic Surgery, Yokohama City University. Address correspondence to Dr. Y. Inaba, Department of Orthopedic Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. E-mail: yute0131@med.yokohama-cu.ac.jp. Accepted for publication February 20, 2014.
Tomoyuki Imagawa
From the Department of Orthopedic Surgery, the Department of Pediatrics, and the Department of Biostatistics and Epidemiology, Yokohama City University, Yokohama, Japan. Dr. Yokota has received consulting and speaking fees from Chugai Pharmaceutical. Drs. Yokota and Miyamae are co-inventors of a patent for juvenile arthritis treatment. C. Aoki, MD; Y. Inaba, MD, PhD, Associate Professor; H. Choe, MD, PhD, Department of Orthopedic Surgery; U. Kaneko, MD; R. Hara, MD, PhD; T. Miyamae, MD, PhD; T. Imagawa, MD, PhD; M. Mori, MD, PhD, Associate Professor, Department of Pediatrics; M.S. Oba, Department of Biostatistics and Epidemiology; S. Yokota, MD, Professor of Pediatrics, Department of Pediatrics; T. Saito, MD, Professor of Orthopedics, Department of Orthopedic Surgery, Yokohama City University. Address correspondence to Dr. Y. Inaba, Department of Orthopedic Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. E-mail: yute0131@med.yokohama-cu.ac.jp. Accepted for publication February 20, 2014.
Masaaki Mori
From the Department of Orthopedic Surgery, the Department of Pediatrics, and the Department of Biostatistics and Epidemiology, Yokohama City University, Yokohama, Japan. Dr. Yokota has received consulting and speaking fees from Chugai Pharmaceutical. Drs. Yokota and Miyamae are co-inventors of a patent for juvenile arthritis treatment. C. Aoki, MD; Y. Inaba, MD, PhD, Associate Professor; H. Choe, MD, PhD, Department of Orthopedic Surgery; U. Kaneko, MD; R. Hara, MD, PhD; T. Miyamae, MD, PhD; T. Imagawa, MD, PhD; M. Mori, MD, PhD, Associate Professor, Department of Pediatrics; M.S. Oba, Department of Biostatistics and Epidemiology; S. Yokota, MD, Professor of Pediatrics, Department of Pediatrics; T. Saito, MD, Professor of Orthopedics, Department of Orthopedic Surgery, Yokohama City University. Address correspondence to Dr. Y. Inaba, Department of Orthopedic Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. E-mail: yute0131@med.yokohama-cu.ac.jp. Accepted for publication February 20, 2014.
Mari S. Oba
From the Department of Orthopedic Surgery, the Department of Pediatrics, and the Department of Biostatistics and Epidemiology, Yokohama City University, Yokohama, Japan. Dr. Yokota has received consulting and speaking fees from Chugai Pharmaceutical. Drs. Yokota and Miyamae are co-inventors of a patent for juvenile arthritis treatment. C. Aoki, MD; Y. Inaba, MD, PhD, Associate Professor; H. Choe, MD, PhD, Department of Orthopedic Surgery; U. Kaneko, MD; R. Hara, MD, PhD; T. Miyamae, MD, PhD; T. Imagawa, MD, PhD; M. Mori, MD, PhD, Associate Professor, Department of Pediatrics; M.S. Oba, Department of Biostatistics and Epidemiology; S. Yokota, MD, Professor of Pediatrics, Department of Pediatrics; T. Saito, MD, Professor of Orthopedics, Department of Orthopedic Surgery, Yokohama City University. Address correspondence to Dr. Y. Inaba, Department of Orthopedic Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. E-mail: yute0131@med.yokohama-cu.ac.jp. Accepted for publication February 20, 2014.
Shumpei Yokota
From the Department of Orthopedic Surgery, the Department of Pediatrics, and the Department of Biostatistics and Epidemiology, Yokohama City University, Yokohama, Japan. Dr. Yokota has received consulting and speaking fees from Chugai Pharmaceutical. Drs. Yokota and Miyamae are co-inventors of a patent for juvenile arthritis treatment. C. Aoki, MD; Y. Inaba, MD, PhD, Associate Professor; H. Choe, MD, PhD, Department of Orthopedic Surgery; U. Kaneko, MD; R. Hara, MD, PhD; T. Miyamae, MD, PhD; T. Imagawa, MD, PhD; M. Mori, MD, PhD, Associate Professor, Department of Pediatrics; M.S. Oba, Department of Biostatistics and Epidemiology; S. Yokota, MD, Professor of Pediatrics, Department of Pediatrics; T. Saito, MD, Professor of Orthopedics, Department of Orthopedic Surgery, Yokohama City University. Address correspondence to Dr. Y. Inaba, Department of Orthopedic Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. E-mail: yute0131@med.yokohama-cu.ac.jp. Accepted for publication February 20, 2014.
Tomoyuki Saito
From the Department of Orthopedic Surgery, the Department of Pediatrics, and the Department of Biostatistics and Epidemiology, Yokohama City University, Yokohama, Japan. Dr. Yokota has received consulting and speaking fees from Chugai Pharmaceutical. Drs. Yokota and Miyamae are co-inventors of a patent for juvenile arthritis treatment. C. Aoki, MD; Y. Inaba, MD, PhD, Associate Professor; H. Choe, MD, PhD, Department of Orthopedic Surgery; U. Kaneko, MD; R. Hara, MD, PhD; T. Miyamae, MD, PhD; T. Imagawa, MD, PhD; M. Mori, MD, PhD, Associate Professor, Department of Pediatrics; M.S. Oba, Department of Biostatistics and Epidemiology; S. Yokota, MD, Professor of Pediatrics, Department of Pediatrics; T. Saito, MD, Professor of Orthopedics, Department of Orthopedic Surgery, Yokohama City University. Address correspondence to Dr. Y. Inaba, Department of Orthopedic Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. E-mail: yute0131@med.yokohama-cu.ac.jp. Accepted for publication February 20, 2014.
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In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Discrepancy Between Clinical and Radiological Responses to Tocilizumab Treatment in Patients with Systemic-onset Juvenile Idiopathic Arthritis
Chie Aoki, Yutaka Inaba, Hyonmin Choe, Utako Kaneko, Ryoki Hara, Takako Miyamae, Tomoyuki Imagawa, Masaaki Mori, Mari S. Oba, Shumpei Yokota, Tomoyuki Saito
The Journal of Rheumatology May 2014, jrheum.130924; DOI: 10.3899/jrheum.130924
Discrepancy Between Clinical and Radiological Responses to Tocilizumab Treatment in Patients with Systemic-onset Juvenile Idiopathic Arthritis
Chie Aoki, Yutaka Inaba, Hyonmin Choe, Utako Kaneko, Ryoki Hara, Takako Miyamae, Tomoyuki Imagawa, Masaaki Mori, Mari S. Oba, Shumpei Yokota, Tomoyuki Saito
The Journal of Rheumatology May 2014, jrheum.130924; DOI: 10.3899/jrheum.130924