Research ArticleArticle
Treatment of Asymptomatic Hyperuricemia and Prevention of Vascular Disease: A Decision Analytic Approach
Roopa Akkineni, Stephanie Tapp, Anna N.A. Tosteson, Alexandra Lee, Katherine L. Miller, Hyon K. Choi, Yanyan Zhu and Daniel A. Albert
The Journal of Rheumatology March 2014, jrheum.121231; DOI: https://doi.org/10.3899/jrheum.121231
Roopa Akkineni
From the Dartmouth-Hitchcock Medical Center, Rheumatology; Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, New Hampshire; Veterans Affairs, VA National Center for Patient Safety, White River Junction, New Hampshire; Northeastern Ohio Universities College of Medicine, Rootstown, Ohio; Boston University School of Medicine, Department of Medicine and Department of Clinical Epidemiology, Boston, Massachusetts, USA. Supported in part by the US National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the US National Institutes of Health (NIH), under Award Number P60-AR062799. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. R. Akkineni, MPH, Dartmouth-Hitchcock Medical Center, Rheumatology; S. Tapp, PhD, Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice; A.N.A. Tosteson, ScD, The Dartmouth Institute for Health Policy and Clinical Practice; A. Lee, MS, Veterans Affairs, VA National Center for Patient Safety; K.L. Miller, MS, Northeastern Ohio Universities College of Medicine; H.K. Choi, MD, DrPH, Boston University School of Medicine, Department of Medicine; Y. Zhu, PhD, Boston University School of Medicine, Department of Clinical Epidemiology; D.A. Albert, MD, Dartmouth-Hitchcock Medical Center. Address correspondence to Dr. D.A. Albert, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, West Lebanon, New Hampshire 03756, USA. E-mail: Daniel.A.Albert@hitchcock.org. Accepted for publication December 13, 2013.
Stephanie Tapp
From the Dartmouth-Hitchcock Medical Center, Rheumatology; Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, New Hampshire; Veterans Affairs, VA National Center for Patient Safety, White River Junction, New Hampshire; Northeastern Ohio Universities College of Medicine, Rootstown, Ohio; Boston University School of Medicine, Department of Medicine and Department of Clinical Epidemiology, Boston, Massachusetts, USA. Supported in part by the US National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the US National Institutes of Health (NIH), under Award Number P60-AR062799. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. R. Akkineni, MPH, Dartmouth-Hitchcock Medical Center, Rheumatology; S. Tapp, PhD, Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice; A.N.A. Tosteson, ScD, The Dartmouth Institute for Health Policy and Clinical Practice; A. Lee, MS, Veterans Affairs, VA National Center for Patient Safety; K.L. Miller, MS, Northeastern Ohio Universities College of Medicine; H.K. Choi, MD, DrPH, Boston University School of Medicine, Department of Medicine; Y. Zhu, PhD, Boston University School of Medicine, Department of Clinical Epidemiology; D.A. Albert, MD, Dartmouth-Hitchcock Medical Center. Address correspondence to Dr. D.A. Albert, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, West Lebanon, New Hampshire 03756, USA. E-mail: Daniel.A.Albert@hitchcock.org. Accepted for publication December 13, 2013.
Anna N.A. Tosteson
From the Dartmouth-Hitchcock Medical Center, Rheumatology; Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, New Hampshire; Veterans Affairs, VA National Center for Patient Safety, White River Junction, New Hampshire; Northeastern Ohio Universities College of Medicine, Rootstown, Ohio; Boston University School of Medicine, Department of Medicine and Department of Clinical Epidemiology, Boston, Massachusetts, USA. Supported in part by the US National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the US National Institutes of Health (NIH), under Award Number P60-AR062799. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. R. Akkineni, MPH, Dartmouth-Hitchcock Medical Center, Rheumatology; S. Tapp, PhD, Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice; A.N.A. Tosteson, ScD, The Dartmouth Institute for Health Policy and Clinical Practice; A. Lee, MS, Veterans Affairs, VA National Center for Patient Safety; K.L. Miller, MS, Northeastern Ohio Universities College of Medicine; H.K. Choi, MD, DrPH, Boston University School of Medicine, Department of Medicine; Y. Zhu, PhD, Boston University School of Medicine, Department of Clinical Epidemiology; D.A. Albert, MD, Dartmouth-Hitchcock Medical Center. Address correspondence to Dr. D.A. Albert, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, West Lebanon, New Hampshire 03756, USA. E-mail: Daniel.A.Albert@hitchcock.org. Accepted for publication December 13, 2013.
Alexandra Lee
From the Dartmouth-Hitchcock Medical Center, Rheumatology; Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, New Hampshire; Veterans Affairs, VA National Center for Patient Safety, White River Junction, New Hampshire; Northeastern Ohio Universities College of Medicine, Rootstown, Ohio; Boston University School of Medicine, Department of Medicine and Department of Clinical Epidemiology, Boston, Massachusetts, USA. Supported in part by the US National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the US National Institutes of Health (NIH), under Award Number P60-AR062799. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. R. Akkineni, MPH, Dartmouth-Hitchcock Medical Center, Rheumatology; S. Tapp, PhD, Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice; A.N.A. Tosteson, ScD, The Dartmouth Institute for Health Policy and Clinical Practice; A. Lee, MS, Veterans Affairs, VA National Center for Patient Safety; K.L. Miller, MS, Northeastern Ohio Universities College of Medicine; H.K. Choi, MD, DrPH, Boston University School of Medicine, Department of Medicine; Y. Zhu, PhD, Boston University School of Medicine, Department of Clinical Epidemiology; D.A. Albert, MD, Dartmouth-Hitchcock Medical Center. Address correspondence to Dr. D.A. Albert, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, West Lebanon, New Hampshire 03756, USA. E-mail: Daniel.A.Albert@hitchcock.org. Accepted for publication December 13, 2013.
Katherine L. Miller
From the Dartmouth-Hitchcock Medical Center, Rheumatology; Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, New Hampshire; Veterans Affairs, VA National Center for Patient Safety, White River Junction, New Hampshire; Northeastern Ohio Universities College of Medicine, Rootstown, Ohio; Boston University School of Medicine, Department of Medicine and Department of Clinical Epidemiology, Boston, Massachusetts, USA. Supported in part by the US National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the US National Institutes of Health (NIH), under Award Number P60-AR062799. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. R. Akkineni, MPH, Dartmouth-Hitchcock Medical Center, Rheumatology; S. Tapp, PhD, Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice; A.N.A. Tosteson, ScD, The Dartmouth Institute for Health Policy and Clinical Practice; A. Lee, MS, Veterans Affairs, VA National Center for Patient Safety; K.L. Miller, MS, Northeastern Ohio Universities College of Medicine; H.K. Choi, MD, DrPH, Boston University School of Medicine, Department of Medicine; Y. Zhu, PhD, Boston University School of Medicine, Department of Clinical Epidemiology; D.A. Albert, MD, Dartmouth-Hitchcock Medical Center. Address correspondence to Dr. D.A. Albert, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, West Lebanon, New Hampshire 03756, USA. E-mail: Daniel.A.Albert@hitchcock.org. Accepted for publication December 13, 2013.
Hyon K. Choi
From the Dartmouth-Hitchcock Medical Center, Rheumatology; Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, New Hampshire; Veterans Affairs, VA National Center for Patient Safety, White River Junction, New Hampshire; Northeastern Ohio Universities College of Medicine, Rootstown, Ohio; Boston University School of Medicine, Department of Medicine and Department of Clinical Epidemiology, Boston, Massachusetts, USA. Supported in part by the US National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the US National Institutes of Health (NIH), under Award Number P60-AR062799. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. R. Akkineni, MPH, Dartmouth-Hitchcock Medical Center, Rheumatology; S. Tapp, PhD, Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice; A.N.A. Tosteson, ScD, The Dartmouth Institute for Health Policy and Clinical Practice; A. Lee, MS, Veterans Affairs, VA National Center for Patient Safety; K.L. Miller, MS, Northeastern Ohio Universities College of Medicine; H.K. Choi, MD, DrPH, Boston University School of Medicine, Department of Medicine; Y. Zhu, PhD, Boston University School of Medicine, Department of Clinical Epidemiology; D.A. Albert, MD, Dartmouth-Hitchcock Medical Center. Address correspondence to Dr. D.A. Albert, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, West Lebanon, New Hampshire 03756, USA. E-mail: Daniel.A.Albert@hitchcock.org. Accepted for publication December 13, 2013.
Yanyan Zhu
From the Dartmouth-Hitchcock Medical Center, Rheumatology; Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, New Hampshire; Veterans Affairs, VA National Center for Patient Safety, White River Junction, New Hampshire; Northeastern Ohio Universities College of Medicine, Rootstown, Ohio; Boston University School of Medicine, Department of Medicine and Department of Clinical Epidemiology, Boston, Massachusetts, USA. Supported in part by the US National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the US National Institutes of Health (NIH), under Award Number P60-AR062799. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. R. Akkineni, MPH, Dartmouth-Hitchcock Medical Center, Rheumatology; S. Tapp, PhD, Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice; A.N.A. Tosteson, ScD, The Dartmouth Institute for Health Policy and Clinical Practice; A. Lee, MS, Veterans Affairs, VA National Center for Patient Safety; K.L. Miller, MS, Northeastern Ohio Universities College of Medicine; H.K. Choi, MD, DrPH, Boston University School of Medicine, Department of Medicine; Y. Zhu, PhD, Boston University School of Medicine, Department of Clinical Epidemiology; D.A. Albert, MD, Dartmouth-Hitchcock Medical Center. Address correspondence to Dr. D.A. Albert, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, West Lebanon, New Hampshire 03756, USA. E-mail: Daniel.A.Albert@hitchcock.org. Accepted for publication December 13, 2013.
Daniel A. Albert
From the Dartmouth-Hitchcock Medical Center, Rheumatology; Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, New Hampshire; Veterans Affairs, VA National Center for Patient Safety, White River Junction, New Hampshire; Northeastern Ohio Universities College of Medicine, Rootstown, Ohio; Boston University School of Medicine, Department of Medicine and Department of Clinical Epidemiology, Boston, Massachusetts, USA. Supported in part by the US National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the US National Institutes of Health (NIH), under Award Number P60-AR062799. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. R. Akkineni, MPH, Dartmouth-Hitchcock Medical Center, Rheumatology; S. Tapp, PhD, Geisel School of Medicine at Dartmouth, The Dartmouth Institute for Health Policy and Clinical Practice; A.N.A. Tosteson, ScD, The Dartmouth Institute for Health Policy and Clinical Practice; A. Lee, MS, Veterans Affairs, VA National Center for Patient Safety; K.L. Miller, MS, Northeastern Ohio Universities College of Medicine; H.K. Choi, MD, DrPH, Boston University School of Medicine, Department of Medicine; Y. Zhu, PhD, Boston University School of Medicine, Department of Clinical Epidemiology; D.A. Albert, MD, Dartmouth-Hitchcock Medical Center. Address correspondence to Dr. D.A. Albert, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, West Lebanon, New Hampshire 03756, USA. E-mail: Daniel.A.Albert@hitchcock.org. Accepted for publication December 13, 2013.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 3
1 Mar 2024
Treatment of Asymptomatic Hyperuricemia and Prevention of Vascular Disease: A Decision Analytic Approach
Roopa Akkineni, Stephanie Tapp, Anna N.A. Tosteson, Alexandra Lee, Katherine L. Miller, Hyon K. Choi, Yanyan Zhu, Daniel A. Albert
The Journal of Rheumatology Mar 2014, jrheum.121231; DOI: 10.3899/jrheum.121231
Treatment of Asymptomatic Hyperuricemia and Prevention of Vascular Disease: A Decision Analytic Approach
Roopa Akkineni, Stephanie Tapp, Anna N.A. Tosteson, Alexandra Lee, Katherine L. Miller, Hyon K. Choi, Yanyan Zhu, Daniel A. Albert
The Journal of Rheumatology Mar 2014, jrheum.121231; DOI: 10.3899/jrheum.121231