Research ArticleArticle
Intraarticular and Systemic Inflammatory Profiles May Identify Patients with Osteoarthritis
Bryan J. Heard, Marvin J. Fritzler, J. Preston Wiley, Jenelle McAllister, Liam Martin, Hani El-Gabalawy, David A. Hart, Cyril B. Frank and Roman Krawetz
The Journal of Rheumatology May 2013, jrheum.121204; DOI: https://doi.org/10.3899/jrheum.121204
Bryan J. Heard
From the McCaig Institute for Bone and Joint Health, the Department of Anatomy and Cell Biology, the Department of Surgery, the Department of Medicine, and the Sports Medicine Centre, Faculty of Kinesiology, University of Calgary, Calgary, Alberta; and the Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada. Supported by an Alberta Innovates — Health Solutions Osteoarthritis Team Grant and a research grant from Pfizer. B.J. Heard, MSc; M.J. Fritzler, MD, PhD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; J.P. Wiley, MD; J. McAllister, MSc, McCaig Institute for Bone and Joint Health, Sports Medicine Centre, Faculty of Kinesiology; L. Martin, MD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; H. El-Gabalawy, MD, Arthritis Centre, University of Manitoba; D.A. Hart, PhD; C.B. Frank, MD, McCaig Institute for Bone and Joint Health, Department of Surgery, University of Calgary; R. Krawetz, PhD, McCaig Institute for Bone and Joint Health, Department of Surgery, Department of Anatomy and Cell Biology, University of Calgary. Address correspondence to Dr. R. Krawetz, McCaig Institute for Bone and Joint Health, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada.E-mail: rkrawetz@ucalgary.ca Accepted for publication March 14, 2013.
Marvin J. Fritzler
From the McCaig Institute for Bone and Joint Health, the Department of Anatomy and Cell Biology, the Department of Surgery, the Department of Medicine, and the Sports Medicine Centre, Faculty of Kinesiology, University of Calgary, Calgary, Alberta; and the Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada. Supported by an Alberta Innovates — Health Solutions Osteoarthritis Team Grant and a research grant from Pfizer. B.J. Heard, MSc; M.J. Fritzler, MD, PhD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; J.P. Wiley, MD; J. McAllister, MSc, McCaig Institute for Bone and Joint Health, Sports Medicine Centre, Faculty of Kinesiology; L. Martin, MD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; H. El-Gabalawy, MD, Arthritis Centre, University of Manitoba; D.A. Hart, PhD; C.B. Frank, MD, McCaig Institute for Bone and Joint Health, Department of Surgery, University of Calgary; R. Krawetz, PhD, McCaig Institute for Bone and Joint Health, Department of Surgery, Department of Anatomy and Cell Biology, University of Calgary. Address correspondence to Dr. R. Krawetz, McCaig Institute for Bone and Joint Health, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada.E-mail: rkrawetz@ucalgary.ca Accepted for publication March 14, 2013.
J. Preston Wiley
From the McCaig Institute for Bone and Joint Health, the Department of Anatomy and Cell Biology, the Department of Surgery, the Department of Medicine, and the Sports Medicine Centre, Faculty of Kinesiology, University of Calgary, Calgary, Alberta; and the Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada. Supported by an Alberta Innovates — Health Solutions Osteoarthritis Team Grant and a research grant from Pfizer. B.J. Heard, MSc; M.J. Fritzler, MD, PhD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; J.P. Wiley, MD; J. McAllister, MSc, McCaig Institute for Bone and Joint Health, Sports Medicine Centre, Faculty of Kinesiology; L. Martin, MD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; H. El-Gabalawy, MD, Arthritis Centre, University of Manitoba; D.A. Hart, PhD; C.B. Frank, MD, McCaig Institute for Bone and Joint Health, Department of Surgery, University of Calgary; R. Krawetz, PhD, McCaig Institute for Bone and Joint Health, Department of Surgery, Department of Anatomy and Cell Biology, University of Calgary. Address correspondence to Dr. R. Krawetz, McCaig Institute for Bone and Joint Health, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada.E-mail: rkrawetz@ucalgary.ca Accepted for publication March 14, 2013.
Jenelle McAllister
From the McCaig Institute for Bone and Joint Health, the Department of Anatomy and Cell Biology, the Department of Surgery, the Department of Medicine, and the Sports Medicine Centre, Faculty of Kinesiology, University of Calgary, Calgary, Alberta; and the Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada. Supported by an Alberta Innovates — Health Solutions Osteoarthritis Team Grant and a research grant from Pfizer. B.J. Heard, MSc; M.J. Fritzler, MD, PhD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; J.P. Wiley, MD; J. McAllister, MSc, McCaig Institute for Bone and Joint Health, Sports Medicine Centre, Faculty of Kinesiology; L. Martin, MD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; H. El-Gabalawy, MD, Arthritis Centre, University of Manitoba; D.A. Hart, PhD; C.B. Frank, MD, McCaig Institute for Bone and Joint Health, Department of Surgery, University of Calgary; R. Krawetz, PhD, McCaig Institute for Bone and Joint Health, Department of Surgery, Department of Anatomy and Cell Biology, University of Calgary. Address correspondence to Dr. R. Krawetz, McCaig Institute for Bone and Joint Health, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada.E-mail: rkrawetz@ucalgary.ca Accepted for publication March 14, 2013.
Liam Martin
From the McCaig Institute for Bone and Joint Health, the Department of Anatomy and Cell Biology, the Department of Surgery, the Department of Medicine, and the Sports Medicine Centre, Faculty of Kinesiology, University of Calgary, Calgary, Alberta; and the Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada. Supported by an Alberta Innovates — Health Solutions Osteoarthritis Team Grant and a research grant from Pfizer. B.J. Heard, MSc; M.J. Fritzler, MD, PhD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; J.P. Wiley, MD; J. McAllister, MSc, McCaig Institute for Bone and Joint Health, Sports Medicine Centre, Faculty of Kinesiology; L. Martin, MD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; H. El-Gabalawy, MD, Arthritis Centre, University of Manitoba; D.A. Hart, PhD; C.B. Frank, MD, McCaig Institute for Bone and Joint Health, Department of Surgery, University of Calgary; R. Krawetz, PhD, McCaig Institute for Bone and Joint Health, Department of Surgery, Department of Anatomy and Cell Biology, University of Calgary. Address correspondence to Dr. R. Krawetz, McCaig Institute for Bone and Joint Health, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada.E-mail: rkrawetz@ucalgary.ca Accepted for publication March 14, 2013.
Hani El-Gabalawy
From the McCaig Institute for Bone and Joint Health, the Department of Anatomy and Cell Biology, the Department of Surgery, the Department of Medicine, and the Sports Medicine Centre, Faculty of Kinesiology, University of Calgary, Calgary, Alberta; and the Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada. Supported by an Alberta Innovates — Health Solutions Osteoarthritis Team Grant and a research grant from Pfizer. B.J. Heard, MSc; M.J. Fritzler, MD, PhD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; J.P. Wiley, MD; J. McAllister, MSc, McCaig Institute for Bone and Joint Health, Sports Medicine Centre, Faculty of Kinesiology; L. Martin, MD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; H. El-Gabalawy, MD, Arthritis Centre, University of Manitoba; D.A. Hart, PhD; C.B. Frank, MD, McCaig Institute for Bone and Joint Health, Department of Surgery, University of Calgary; R. Krawetz, PhD, McCaig Institute for Bone and Joint Health, Department of Surgery, Department of Anatomy and Cell Biology, University of Calgary. Address correspondence to Dr. R. Krawetz, McCaig Institute for Bone and Joint Health, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada.E-mail: rkrawetz@ucalgary.ca Accepted for publication March 14, 2013.
David A. Hart
From the McCaig Institute for Bone and Joint Health, the Department of Anatomy and Cell Biology, the Department of Surgery, the Department of Medicine, and the Sports Medicine Centre, Faculty of Kinesiology, University of Calgary, Calgary, Alberta; and the Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada. Supported by an Alberta Innovates — Health Solutions Osteoarthritis Team Grant and a research grant from Pfizer. B.J. Heard, MSc; M.J. Fritzler, MD, PhD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; J.P. Wiley, MD; J. McAllister, MSc, McCaig Institute for Bone and Joint Health, Sports Medicine Centre, Faculty of Kinesiology; L. Martin, MD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; H. El-Gabalawy, MD, Arthritis Centre, University of Manitoba; D.A. Hart, PhD; C.B. Frank, MD, McCaig Institute for Bone and Joint Health, Department of Surgery, University of Calgary; R. Krawetz, PhD, McCaig Institute for Bone and Joint Health, Department of Surgery, Department of Anatomy and Cell Biology, University of Calgary. Address correspondence to Dr. R. Krawetz, McCaig Institute for Bone and Joint Health, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada.E-mail: rkrawetz@ucalgary.ca Accepted for publication March 14, 2013.
Cyril B. Frank
From the McCaig Institute for Bone and Joint Health, the Department of Anatomy and Cell Biology, the Department of Surgery, the Department of Medicine, and the Sports Medicine Centre, Faculty of Kinesiology, University of Calgary, Calgary, Alberta; and the Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada. Supported by an Alberta Innovates — Health Solutions Osteoarthritis Team Grant and a research grant from Pfizer. B.J. Heard, MSc; M.J. Fritzler, MD, PhD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; J.P. Wiley, MD; J. McAllister, MSc, McCaig Institute for Bone and Joint Health, Sports Medicine Centre, Faculty of Kinesiology; L. Martin, MD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; H. El-Gabalawy, MD, Arthritis Centre, University of Manitoba; D.A. Hart, PhD; C.B. Frank, MD, McCaig Institute for Bone and Joint Health, Department of Surgery, University of Calgary; R. Krawetz, PhD, McCaig Institute for Bone and Joint Health, Department of Surgery, Department of Anatomy and Cell Biology, University of Calgary. Address correspondence to Dr. R. Krawetz, McCaig Institute for Bone and Joint Health, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada.E-mail: rkrawetz@ucalgary.ca Accepted for publication March 14, 2013.
Roman Krawetz
From the McCaig Institute for Bone and Joint Health, the Department of Anatomy and Cell Biology, the Department of Surgery, the Department of Medicine, and the Sports Medicine Centre, Faculty of Kinesiology, University of Calgary, Calgary, Alberta; and the Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada. Supported by an Alberta Innovates — Health Solutions Osteoarthritis Team Grant and a research grant from Pfizer. B.J. Heard, MSc; M.J. Fritzler, MD, PhD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; J.P. Wiley, MD; J. McAllister, MSc, McCaig Institute for Bone and Joint Health, Sports Medicine Centre, Faculty of Kinesiology; L. Martin, MD, McCaig Institute for Bone and Joint Health, Department of Medicine, University of Calgary; H. El-Gabalawy, MD, Arthritis Centre, University of Manitoba; D.A. Hart, PhD; C.B. Frank, MD, McCaig Institute for Bone and Joint Health, Department of Surgery, University of Calgary; R. Krawetz, PhD, McCaig Institute for Bone and Joint Health, Department of Surgery, Department of Anatomy and Cell Biology, University of Calgary. Address correspondence to Dr. R. Krawetz, McCaig Institute for Bone and Joint Health, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada.E-mail: rkrawetz@ucalgary.ca Accepted for publication March 14, 2013.
In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Intraarticular and Systemic Inflammatory Profiles May Identify Patients with Osteoarthritis
Bryan J. Heard, Marvin J. Fritzler, J. Preston Wiley, Jenelle McAllister, Liam Martin, Hani El-Gabalawy, David A. Hart, Cyril B. Frank, Roman Krawetz
The Journal of Rheumatology May 2013, jrheum.121204; DOI: 10.3899/jrheum.121204
Intraarticular and Systemic Inflammatory Profiles May Identify Patients with Osteoarthritis
Bryan J. Heard, Marvin J. Fritzler, J. Preston Wiley, Jenelle McAllister, Liam Martin, Hani El-Gabalawy, David A. Hart, Cyril B. Frank, Roman Krawetz
The Journal of Rheumatology May 2013, jrheum.121204; DOI: 10.3899/jrheum.121204