Research ArticleArticle
Comparison of Blood and Synovial Fluid Th17 and Novel Peptidase Inhibitor 16 Treg Cell Subsets in Juvenile Idiopathic Arthritis
Randall H. Grose, Deborah J. Millard, Chris Mavrangelos, Simon C. Barry, Heddy Zola, Ian C. Nicholson, Weng Tarng Cham, Christina A. Boros and Doreen Krumbiegel
The Journal of Rheumatology August 2012, jrheum.111421; DOI: https://doi.org/10.3899/jrheum.111421
Randall H. Grose
From the Women’s and Children’s Health Research Institute (WCHRI), North Adelaide, and the Discipline of Paediatrics, University of Adelaide, Adelaide, Australia. Supported by the Co-operative Research Centre (CRC) for Biomarker Translation, Australia. R.H. Grose, PhD; D.J. Millard, Dip Biomed; C. Mavrangelos, BSc, WCHRI, Leukocyte Biology Laboratory, CRC for Biomarker Translation; S.C. Barry, PhD, WCHRI, Leukocyte Biology Laboratory, Molecular Immunology Laboratory, and Department of Gastroenterology, Children, Youth and Women’s Health Service, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; H. Zola, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; I.C. Nicholson, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, Flinders University, CRC for Biomarker Translation; W.T. Cham, MBBS, MRCPCH; C.A. Boros, MBBS, PhD, FRACP, Department of Rheumatology, Women’s and Children’s Hospital, Discipline of Paediatrics, University of Adelaide; D. Krumbiegel, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, CRC for Biomarker Translation. Dr. Boros and Dr. Krumbiegel contributed equally to the study. Address correspondence to Dr. D. Krumbiegel, Women’s and Children’s Health Research Institute, 72 King William Road, North Adelaide, SA 5006, Australia. E-mail: doreen.krumbiegel@adelaide.edu.au Accepted for publication June 4, 2012.
Deborah J. Millard
From the Women’s and Children’s Health Research Institute (WCHRI), North Adelaide, and the Discipline of Paediatrics, University of Adelaide, Adelaide, Australia. Supported by the Co-operative Research Centre (CRC) for Biomarker Translation, Australia. R.H. Grose, PhD; D.J. Millard, Dip Biomed; C. Mavrangelos, BSc, WCHRI, Leukocyte Biology Laboratory, CRC for Biomarker Translation; S.C. Barry, PhD, WCHRI, Leukocyte Biology Laboratory, Molecular Immunology Laboratory, and Department of Gastroenterology, Children, Youth and Women’s Health Service, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; H. Zola, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; I.C. Nicholson, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, Flinders University, CRC for Biomarker Translation; W.T. Cham, MBBS, MRCPCH; C.A. Boros, MBBS, PhD, FRACP, Department of Rheumatology, Women’s and Children’s Hospital, Discipline of Paediatrics, University of Adelaide; D. Krumbiegel, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, CRC for Biomarker Translation. Dr. Boros and Dr. Krumbiegel contributed equally to the study. Address correspondence to Dr. D. Krumbiegel, Women’s and Children’s Health Research Institute, 72 King William Road, North Adelaide, SA 5006, Australia. E-mail: doreen.krumbiegel@adelaide.edu.au Accepted for publication June 4, 2012.
Chris Mavrangelos
From the Women’s and Children’s Health Research Institute (WCHRI), North Adelaide, and the Discipline of Paediatrics, University of Adelaide, Adelaide, Australia. Supported by the Co-operative Research Centre (CRC) for Biomarker Translation, Australia. R.H. Grose, PhD; D.J. Millard, Dip Biomed; C. Mavrangelos, BSc, WCHRI, Leukocyte Biology Laboratory, CRC for Biomarker Translation; S.C. Barry, PhD, WCHRI, Leukocyte Biology Laboratory, Molecular Immunology Laboratory, and Department of Gastroenterology, Children, Youth and Women’s Health Service, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; H. Zola, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; I.C. Nicholson, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, Flinders University, CRC for Biomarker Translation; W.T. Cham, MBBS, MRCPCH; C.A. Boros, MBBS, PhD, FRACP, Department of Rheumatology, Women’s and Children’s Hospital, Discipline of Paediatrics, University of Adelaide; D. Krumbiegel, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, CRC for Biomarker Translation. Dr. Boros and Dr. Krumbiegel contributed equally to the study. Address correspondence to Dr. D. Krumbiegel, Women’s and Children’s Health Research Institute, 72 King William Road, North Adelaide, SA 5006, Australia. E-mail: doreen.krumbiegel@adelaide.edu.au Accepted for publication June 4, 2012.
Simon C. Barry
From the Women’s and Children’s Health Research Institute (WCHRI), North Adelaide, and the Discipline of Paediatrics, University of Adelaide, Adelaide, Australia. Supported by the Co-operative Research Centre (CRC) for Biomarker Translation, Australia. R.H. Grose, PhD; D.J. Millard, Dip Biomed; C. Mavrangelos, BSc, WCHRI, Leukocyte Biology Laboratory, CRC for Biomarker Translation; S.C. Barry, PhD, WCHRI, Leukocyte Biology Laboratory, Molecular Immunology Laboratory, and Department of Gastroenterology, Children, Youth and Women’s Health Service, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; H. Zola, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; I.C. Nicholson, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, Flinders University, CRC for Biomarker Translation; W.T. Cham, MBBS, MRCPCH; C.A. Boros, MBBS, PhD, FRACP, Department of Rheumatology, Women’s and Children’s Hospital, Discipline of Paediatrics, University of Adelaide; D. Krumbiegel, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, CRC for Biomarker Translation. Dr. Boros and Dr. Krumbiegel contributed equally to the study. Address correspondence to Dr. D. Krumbiegel, Women’s and Children’s Health Research Institute, 72 King William Road, North Adelaide, SA 5006, Australia. E-mail: doreen.krumbiegel@adelaide.edu.au Accepted for publication June 4, 2012.
Heddy Zola
From the Women’s and Children’s Health Research Institute (WCHRI), North Adelaide, and the Discipline of Paediatrics, University of Adelaide, Adelaide, Australia. Supported by the Co-operative Research Centre (CRC) for Biomarker Translation, Australia. R.H. Grose, PhD; D.J. Millard, Dip Biomed; C. Mavrangelos, BSc, WCHRI, Leukocyte Biology Laboratory, CRC for Biomarker Translation; S.C. Barry, PhD, WCHRI, Leukocyte Biology Laboratory, Molecular Immunology Laboratory, and Department of Gastroenterology, Children, Youth and Women’s Health Service, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; H. Zola, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; I.C. Nicholson, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, Flinders University, CRC for Biomarker Translation; W.T. Cham, MBBS, MRCPCH; C.A. Boros, MBBS, PhD, FRACP, Department of Rheumatology, Women’s and Children’s Hospital, Discipline of Paediatrics, University of Adelaide; D. Krumbiegel, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, CRC for Biomarker Translation. Dr. Boros and Dr. Krumbiegel contributed equally to the study. Address correspondence to Dr. D. Krumbiegel, Women’s and Children’s Health Research Institute, 72 King William Road, North Adelaide, SA 5006, Australia. E-mail: doreen.krumbiegel@adelaide.edu.au Accepted for publication June 4, 2012.
Ian C. Nicholson
From the Women’s and Children’s Health Research Institute (WCHRI), North Adelaide, and the Discipline of Paediatrics, University of Adelaide, Adelaide, Australia. Supported by the Co-operative Research Centre (CRC) for Biomarker Translation, Australia. R.H. Grose, PhD; D.J. Millard, Dip Biomed; C. Mavrangelos, BSc, WCHRI, Leukocyte Biology Laboratory, CRC for Biomarker Translation; S.C. Barry, PhD, WCHRI, Leukocyte Biology Laboratory, Molecular Immunology Laboratory, and Department of Gastroenterology, Children, Youth and Women’s Health Service, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; H. Zola, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; I.C. Nicholson, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, Flinders University, CRC for Biomarker Translation; W.T. Cham, MBBS, MRCPCH; C.A. Boros, MBBS, PhD, FRACP, Department of Rheumatology, Women’s and Children’s Hospital, Discipline of Paediatrics, University of Adelaide; D. Krumbiegel, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, CRC for Biomarker Translation. Dr. Boros and Dr. Krumbiegel contributed equally to the study. Address correspondence to Dr. D. Krumbiegel, Women’s and Children’s Health Research Institute, 72 King William Road, North Adelaide, SA 5006, Australia. E-mail: doreen.krumbiegel@adelaide.edu.au Accepted for publication June 4, 2012.
Weng Tarng Cham
From the Women’s and Children’s Health Research Institute (WCHRI), North Adelaide, and the Discipline of Paediatrics, University of Adelaide, Adelaide, Australia. Supported by the Co-operative Research Centre (CRC) for Biomarker Translation, Australia. R.H. Grose, PhD; D.J. Millard, Dip Biomed; C. Mavrangelos, BSc, WCHRI, Leukocyte Biology Laboratory, CRC for Biomarker Translation; S.C. Barry, PhD, WCHRI, Leukocyte Biology Laboratory, Molecular Immunology Laboratory, and Department of Gastroenterology, Children, Youth and Women’s Health Service, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; H. Zola, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; I.C. Nicholson, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, Flinders University, CRC for Biomarker Translation; W.T. Cham, MBBS, MRCPCH; C.A. Boros, MBBS, PhD, FRACP, Department of Rheumatology, Women’s and Children’s Hospital, Discipline of Paediatrics, University of Adelaide; D. Krumbiegel, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, CRC for Biomarker Translation. Dr. Boros and Dr. Krumbiegel contributed equally to the study. Address correspondence to Dr. D. Krumbiegel, Women’s and Children’s Health Research Institute, 72 King William Road, North Adelaide, SA 5006, Australia. E-mail: doreen.krumbiegel@adelaide.edu.au Accepted for publication June 4, 2012.
Christina A. Boros
From the Women’s and Children’s Health Research Institute (WCHRI), North Adelaide, and the Discipline of Paediatrics, University of Adelaide, Adelaide, Australia. Supported by the Co-operative Research Centre (CRC) for Biomarker Translation, Australia. R.H. Grose, PhD; D.J. Millard, Dip Biomed; C. Mavrangelos, BSc, WCHRI, Leukocyte Biology Laboratory, CRC for Biomarker Translation; S.C. Barry, PhD, WCHRI, Leukocyte Biology Laboratory, Molecular Immunology Laboratory, and Department of Gastroenterology, Children, Youth and Women’s Health Service, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; H. Zola, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; I.C. Nicholson, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, Flinders University, CRC for Biomarker Translation; W.T. Cham, MBBS, MRCPCH; C.A. Boros, MBBS, PhD, FRACP, Department of Rheumatology, Women’s and Children’s Hospital, Discipline of Paediatrics, University of Adelaide; D. Krumbiegel, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, CRC for Biomarker Translation. Dr. Boros and Dr. Krumbiegel contributed equally to the study. Address correspondence to Dr. D. Krumbiegel, Women’s and Children’s Health Research Institute, 72 King William Road, North Adelaide, SA 5006, Australia. E-mail: doreen.krumbiegel@adelaide.edu.au Accepted for publication June 4, 2012.
Doreen Krumbiegel
From the Women’s and Children’s Health Research Institute (WCHRI), North Adelaide, and the Discipline of Paediatrics, University of Adelaide, Adelaide, Australia. Supported by the Co-operative Research Centre (CRC) for Biomarker Translation, Australia. R.H. Grose, PhD; D.J. Millard, Dip Biomed; C. Mavrangelos, BSc, WCHRI, Leukocyte Biology Laboratory, CRC for Biomarker Translation; S.C. Barry, PhD, WCHRI, Leukocyte Biology Laboratory, Molecular Immunology Laboratory, and Department of Gastroenterology, Children, Youth and Women’s Health Service, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; H. Zola, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, and CRC for Biomarker Translation; I.C. Nicholson, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, Flinders University, CRC for Biomarker Translation; W.T. Cham, MBBS, MRCPCH; C.A. Boros, MBBS, PhD, FRACP, Department of Rheumatology, Women’s and Children’s Hospital, Discipline of Paediatrics, University of Adelaide; D. Krumbiegel, PhD, WCHRI, Leukocyte Biology Laboratory, Discipline of Paediatrics, University of Adelaide, CRC for Biomarker Translation. Dr. Boros and Dr. Krumbiegel contributed equally to the study. Address correspondence to Dr. D. Krumbiegel, Women’s and Children’s Health Research Institute, 72 King William Road, North Adelaide, SA 5006, Australia. E-mail: doreen.krumbiegel@adelaide.edu.au Accepted for publication June 4, 2012.
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In this issue
The Journal of Rheumatology
Vol. 51, Issue 4
1 Apr 2024
Comparison of Blood and Synovial Fluid Th17 and Novel Peptidase Inhibitor 16 Treg Cell Subsets in Juvenile Idiopathic Arthritis
Randall H. Grose, Deborah J. Millard, Chris Mavrangelos, Simon C. Barry, Heddy Zola, Ian C. Nicholson, Weng Tarng Cham, Christina A. Boros, Doreen Krumbiegel
The Journal of Rheumatology Aug 2012, jrheum.111421; DOI: 10.3899/jrheum.111421
Comparison of Blood and Synovial Fluid Th17 and Novel Peptidase Inhibitor 16 Treg Cell Subsets in Juvenile Idiopathic Arthritis
Randall H. Grose, Deborah J. Millard, Chris Mavrangelos, Simon C. Barry, Heddy Zola, Ian C. Nicholson, Weng Tarng Cham, Christina A. Boros, Doreen Krumbiegel
The Journal of Rheumatology Aug 2012, jrheum.111421; DOI: 10.3899/jrheum.111421