Research ArticleArticle
A Phase III, Randomized, Controlled Trial of Apremilast in Patients with Psoriatic Arthritis: Results of the PALACE 2 Trial
Maurizio Cutolo, Gary E. Myerson, Roy M. Fleischmann, Frédéric Lioté, Federico Díaz-González, Filip Van den Bosch, Helena Marzo-Ortega, Eugen Feist, Kamal Shah, ChiaChi Hu, Randall M. Stevens and Airi Poder
The Journal of Rheumatology September 2016, 43 (9) 1724-1734; DOI: https://doi.org/10.3899/jrheum.151376
Maurizio Cutolo
From the Research Laboratory and Division of Clinical Rheumatology, University of Genoa, Genoa,
Italy; Arthritis and Rheumatology of Georgia, Atlanta,
Georgia; Metroplex Clinical Research Center, Dallas, Texas,
USA; AP-HP, Hôpital Lariboisière, Rheumatology Department, Université Paris Diderot, Paris,
France; University of La Laguna, Hospital Universitario de Canarias, La Laguna,
Spain; UZ Gent, Ghent,
Belgium; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds,
UK; Charité – Universitätsmedizin Berlin, Department for Rheumatology and Clinical Immunology, Berlin,
Germany; Celgene Corp., Summit, New Jersey,
USA; Clinical Research Centre Ltd., Tartu,
Estonia.
Gary E. Myerson
Roy M. Fleischmann
Frédéric Lioté
Federico Díaz-González
Filip Van den Bosch
Helena Marzo-Ortega
Eugen Feist
Kamal Shah
ChiaChi Hu
Randall M. Stevens
REFERENCES
- 1.↵
- Gladman DD,
- Antoni C,
- Mease P,
- Clegg DO,
- Nash P
- 2.↵
- Strand V,
- Sharp V,
- Koenig AS,
- Park G,
- Shi Y,
- Wang B,
- et al.
- 3.↵
- Singh JA,
- Strand V
- 4.↵
- Zhu TY,
- Tam LS,
- Leung YY,
- Kwok LW,
- Wong KC,
- Yu T,
- et al.
- 5.↵
- Sokoll KB,
- Helliwell PS
- 6.↵
- Smolen JS,
- Braun J,
- Dougados M,
- Emery P,
- Fitzgerald O,
- Helliwell P,
- et al.
- 7.↵
- 8.↵
- Kingsley GH,
- Kowalczyk A,
- Taylor H,
- Ibrahim F,
- Packham JC,
- McHugh NJ,
- et al.
- 9.↵
- Fraser AD,
- van Kuijk AW,
- Westhovens R,
- Karim Z,
- Wakefield R,
- Gerards AH,
- et al.
- 10.↵
- Salvarani C,
- Macchioni P,
- Olivieri I,
- Marchesoni A,
- Cutolo M,
- Ferraccioli G,
- et al.
- 11.↵
- Fagerli KM,
- Lie E,
- van der Heijde D,
- Heiberg MS,
- Lexberg AS,
- Rodevand E,
- et al.
- 12.↵
- Menter A,
- Gottlieb A,
- Feldman SR,
- Van Voorhees AS,
- Leonardi CL,
- Gordon KB,
- et al.
- 13.↵
- Menter A,
- Korman NJ,
- Elmets CA,
- Feldman SR,
- Gelfand JM,
- Gordon KB,
- et al.
- 14.↵
- Ash Z,
- Gaujoux-Viala C,
- Gossec L,
- Hensor EM,
- Fitzgerald O,
- Winthrop K,
- et al.
- 15.↵
- Kavanaugh A,
- Puig L,
- Gottlieb AB,
- Ritchlin C,
- Li S,
- Wang Y,
- et al.
- 16.↵
- van der Heijde D,
- Landewe RB,
- Mease PJ,
- McInnes IB,
- Conaghan PG,
- Pricop L,
- et al.
- 17.↵
- Gossec L,
- Smolen JS,
- Gaujoux-Viala C,
- Ash Z,
- Marzo-Ortega H,
- van der Heijde D,
- et al.
- 18.↵
- Ramiro S,
- Gaujoux-Viala C,
- Nam JL,
- Smolen JS,
- Buch M,
- Gossec L,
- et al.
- 19.↵
- 20.↵
- 21.↵
- Schafer PH,
- Chen P,
- Fang L,
- Wang A,
- Chopra R
- 22.↵
- Edwards CJ,
- Blanco FJ,
- Crowley J,
- Birbara CA,
- Jaworski J,
- Aelion J,
- et al.
- 23.↵
- 24.↵
- 25.↵
- 26.↵
- Kwok T,
- Pope JE
- 27.↵
- Mease PJ,
- Ganguly R,
- Wanke L,
- Yu E,
- Singh A
- 28.↵
- Mease PJ,
- Woolley JM,
- Bitman B,
- Wang BC,
- Globe DR,
- Singh A
- 29.↵
- 30.↵
- 31.↵
- 32.↵
- 33.↵
- Kavanaugh A,
- Mease PJ,
- Gomez-Reino JJ,
- Adebajo AO,
- Wollenhaupt J,
- Gladman DD,
- et al.
- 34.↵
- Kavanaugh A,
- Mease PJ,
- Gomez-Reino JJ,
- Adebajo AO,
- Wollenhaupt J,
- Gladman DD,
- et al.
In this issue
The Journal of Rheumatology
Vol. 43, Issue 9
1 Sep 2016
A Phase III, Randomized, Controlled Trial of Apremilast in Patients with Psoriatic Arthritis: Results of the PALACE 2 Trial
Maurizio Cutolo, Gary E. Myerson, Roy M. Fleischmann, Frédéric Lioté, Federico Díaz-González, Filip Van den Bosch, Helena Marzo-Ortega, Eugen Feist, Kamal Shah, ChiaChi Hu, Randall M. Stevens, Airi Poder
The Journal of Rheumatology Sep 2016, 43 (9) 1724-1734; DOI: 10.3899/jrheum.151376
A Phase III, Randomized, Controlled Trial of Apremilast in Patients with Psoriatic Arthritis: Results of the PALACE 2 Trial
Maurizio Cutolo, Gary E. Myerson, Roy M. Fleischmann, Frédéric Lioté, Federico Díaz-González, Filip Van den Bosch, Helena Marzo-Ortega, Eugen Feist, Kamal Shah, ChiaChi Hu, Randall M. Stevens, Airi Poder
The Journal of Rheumatology Sep 2016, 43 (9) 1724-1734; DOI: 10.3899/jrheum.151376