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Objective. To determine the association of use of tumor necrosis factor-α (TNF-α) inhibitors with differences in lipid levels in patients with rheumatoid arthritis (RA).
Methods. We studied 807 patients with incident RA to compare differences in lipid levels in TNF-α inhibitor users versus nonusers, with adjustment for relevant covariables.
Results. TNF-α inhibitor use was not associated with differences in levels of low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TC), triglycerides, LDL:HDL, or TC:HDL compared to nonusers.
Conclusion. Use of TNF-α inhibitor was not associated with differences in lipid levels in patients with RA.
Supported by Amgen/Wyeth.
- Accepted for publication January 17, 2012.