Excerpt
It is my pleasure to present the Dunlop-Dotteridge Lecture for 2008.
This has been an exciting decade for advances in the treatment of rheumatoid arthritis (RA). There are, however, many questions remaining about the use of our therapies in the treatment of this disease.
Are tumor necrosis factor (TNF) inhibitors effective?
The answer is a resounding yes. There have been multiple randomized trials as part of the development programs of the 3 approved anti-TNF therapies. There has been a consistency of response with all 3 therapies, whether used as monotherapy or in combination with methotrexate (MTX). If one uses the…