Excerpt
To the Editor:
Central nervous system (CNS) involvement in systemic lupus erythematosus (SLE) is common, with 25% to 60% of patients having neurological symptoms, and a higher percentage displaying CNS pathology in imaging studies or on post mortem examination1,2. The most common clinical manifestations are cognitive decline, psychosis, seizures, and strokes. Abnormalities on magnetic resonance imaging (MRI) scans are usually nonspecific, such as cortical atrophy or scattered focal high-intensity white-matter signals3. Occasionally, larger infarcts or hemorrhages may be seen. We describe a young girl with CNS lupus who presented with the very uncommon MRI findings of hyperintense lesions in the…